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  1. Content type: Research

    Lung segmentation constitutes a critical procedure for any clinical-decision supporting system aimed to improve the early diagnosis and treatment of lung diseases. Abnormal lungs mainly include lung parenchyma...

    Authors: Mingjie Xu, Shouliang Qi, Yong Yue, Yueyang Teng, Lisheng Xu, Yudong Yao and Wei Qian

    Citation: BioMedical Engineering OnLine 2019 18:2

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  2. Content type: Research

    There exists a growing need for a cost-effective, reliable, and portable pulsation simulator that can generate a wide variety of pulses depending on age and cardiovascular disease. For constructing compact pul...

    Authors: Tae-Heon Yang, Gwanghyun Jo, Jeong-Hoi Koo, Sam-Yong Woo, Jaeuk U. Kim and Young-Min Kim

    Citation: BioMedical Engineering OnLine 2019 18:1

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  3. Content type: Research

    Optical imaging is one of the most common, low-cost imaging tools used for investigating the tumor biological behavior in vivo. This study explores the feasibility and sensitivity of a near infrared fluorescen...

    Authors: Kedi Zhou, Yichen Ding, Ivan Vuletic, Yonglu Tian, Jun Li, Jinghao Liu, Yixing Huang, Hongfang Sun, Changhui Li, Qiushi Ren and Yanye Lu

    Citation: BioMedical Engineering OnLine 2018 17:187

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  4. Content type: Research

    Electrical impedance tomography (EIT) is an emerging imaging technology that has been used to monitor brain injury and detect acute stroke. The time and frequency properties of electrode–skin contact impedance...

    Authors: Lin Yang, Heng Li, Junjie Ding, Weichen Li, Xiuzhen Dong, Zhihong Wen and Xuetao Shi

    Citation: BioMedical Engineering OnLine 2018 17:186

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  5. Content type: Research

    Detection and quantification of cyclic alternating patterns (CAP) components has the potential to serve as a disease bio-marker. Few methods exist to discriminate all the different CAP components, they do not ...

    Authors: Fátima Machado, Francisco Sales, Clara Santos, António Dourado and C. A. Teixeira

    Citation: BioMedical Engineering OnLine 2018 17:185

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  6. Content type: Research

    Phase-rectified signal averaging (PRSA) was often applied to assess the cardiac vagal modulation. Despite its broad use, this method suffers from the confounding effects of anomalous variants of sinus rhythm. ...

    Authors: Hongyun Liu, Ping Zhan, Jinlong Shi, Guojing Wang, Buqing Wang and Weidong Wang

    Citation: BioMedical Engineering OnLine 2018 17:184

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  7. Content type: Research

    Mobile health apps (mHealth apps) are increasing in popularity and utility for the management of many chronic diseases. Although the current reimbursement structure for mHealth apps is lagging behind the rapid...

    Authors: Alice Lan, Alexandra Lee, Kristin Munroe, Cameron McRae, Linda Kaleis, Karim Keshavjee and Aziz Guergachi

    Citation: BioMedical Engineering OnLine 2018 17:183

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  8. Content type: Research

    Myocardial deformation measured by strain is used to detect electro-mechanical abnormalities in cardiac tissue. Estimation of myocardial properties from regional strain patterns when multiple pathologies are p...

    Authors: Borut Kirn, John Walmsley and Joost Lumens

    Citation: BioMedical Engineering OnLine 2018 17:182

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  10. Content type: Research

    The study presents a recursive least-squares estimation method with an exponential forgetting factor for noise removal in functional near-infrared spectroscopy data and extraction of hemodynamic responses (HRs...

    Authors: Hoang-Dung Nguyen, So-Hyeon Yoo, M. Raheel Bhutta and Keum-Shik Hong

    Citation: BioMedical Engineering OnLine 2018 17:180

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  13. Content type: Research

    Sit-to-stand movements are a necessary part of daily life, and excessive mechanical stress on the articular cartilage has been reported to encourage the progression of osteoarthritis. Although a change in hip ...

    Authors: Takuma Inai, Tomoya Takabayashi, Mutsuaki Edama and Masayoshi Kubo

    Citation: BioMedical Engineering OnLine 2018 17:177

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  14. Content type: Research

    This paper presents a novel method for early detection of hematomas using highly sensitive optical fNIR imaging methods based on broadband photon migration. The NIR experimental measurements of inhomogeneous m...

    Authors: E. Sultan, A. H. Gandjbakhche, K. Pourrezaei and A. S. Daryoush

    Citation: BioMedical Engineering OnLine 2018 17:176

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  16. Content type: Research

    A number of various techniques were proposed to stabilized ankle arthrodesis, among them external and internal fixation. Appropriate balance and adequate distribution of lower limb loads determine normal biome...

    Authors: Piotr Morasiewicz, Grzegorz Konieczny, Maciej Dejnek, Leszek Morasiewicz, Wiktor Urbański, Mirosław Kulej, Szymon Łukasz Dragan, Szymon Feliks Dragan and Łukasz Pawik

    Citation: BioMedical Engineering OnLine 2018 17:174

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  17. Content type: Research

    Preparation of a uniform angle of walls is essential for making an ideal convergence angle in fixed prosthodontics. We developed a de novo detachable angle-correction apparatus for dental handpiece drills that...

    Authors: Yoon Nam, Mi Young Eo and Soung Min Kim

    Citation: BioMedical Engineering OnLine 2018 17:173

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  18. Content type: Research

    The periodontal ligament (PDL) plays a key role in alveolar bone remodeling and resorption during tooth movements. The prediction of tooth mobility under functional dental loads requires a deep understanding o...

    Authors: Bin Wu, Yipeng Fu, Haotian Shi, Bin Yan, Ruxin Lu, Songyun Ma and Bernd Markert

    Citation: BioMedical Engineering OnLine 2018 17:172

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  19. Content type: Research

    This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical di...

    Authors: Shaun Davidson, Chris Pretty, Joel Balmer, Thomas Desaive and J. Geoffrey Chase

    Citation: BioMedical Engineering OnLine 2018 17:171

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  21. Content type: Research

    Extracting fundamental information from data, thus underlining hidden structures or removing noisy information, is one of the most important aims in different scientific fields especially in biological and med...

    Authors: Nicola Amoroso, Domenico Diacono, Marianna La Rocca, Roberto Bellotti and Sabina Tangaro

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):162

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    This article is part of a Supplement: Volume 17 Supplement 1

  22. Content type: Research

    In case of significant imperfections on the cornea, data acquisition is difficult and a significant level of missing data could require the interpolation of important areas of the cornea, resulting in a very a...

    Authors: Francisco Cavas-Martínez, Daniel G. Fernández-Pacheco, Dolores Parras, Francisco J. F. Cañavate, Laurent Bataille and Jorge Alió

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):161

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    This article is part of a Supplement: Volume 17 Supplement 1

  23. Content type: Research

    Like other scientific fields, such as cosmology, high-energy physics, or even the life sciences, medicine and healthcare face the challenge of an extremely quick transformation into data-driven sciences. This ...

    Authors: Alfredo Vellido, Vicent Ribas, Carles Morales, Adolfo Ruiz Sanmartín and Juan Carlos Ruiz Rodríguez

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):135

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  24. Content type: Research

    Laboratory rats play a critical role in research because they provide a biological model that can be used for evaluating the affectation of diseases and injuries, and for the evaluation of the effectiveness of...

    Authors: S. Ivvan Valdez, Josué González-Sandoval, Sergio Dueñas-Jiménez, Nancy Elizabeth Franco Rodríguez, Sulema Torres-Ramos and Gerardo Mendizabal-Ruiz

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):134

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  25. Content type: Research

    Pseudomonas aeruginosa is a common bacterium which is recognized for its association with hospital-acquired infections and its advanced antibiotic resistance mechanisms. Tuberculosis, one of the major causes of m...

    Authors: Dan Wang, Jingyu Li and Lusheng Wang

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):133

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  26. Content type: Research

    The human activity monitoring technology is one of the most important technologies for ambient assisted living, surveillance-based security, sport and fitness activities, healthcare of elderly people. The acti...

    Authors: Giorgio Biagetti, Paolo Crippa, Laura Falaschetti, Simone Orcioni and Claudio Turchetti

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):132

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    This article is part of a Supplement: Volume 17 Supplement 1

  27. Content type: Research

    This paper studies the temporal consistency of health care expenditures in a large state Medicaid program. Predictive machine learning models were used to forecast the expenditures, especially for the high-cos...

    Authors: Chengliang Yang, Chris Delcher, Elizabeth Shenkman and Sanjay Ranka

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):131

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    This article is part of a Supplement: Volume 17 Supplement 1

  28. Content type: Review

    Mechanical ventilation is an essential therapy to support critically ill respiratory failure patients. Current standards of care consist of generalised approaches, such as the use of positive end expiratory pr...

    Authors: Vincent J. Major, Yeong Shiong Chiew, Geoffrey M. Shaw and J. Geoffrey Chase

    Citation: BioMedical Engineering OnLine 2018 17:169

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  29. Content type: Research

    The main objective of this paper is to develop and test the ability of the Leap Motion controller (LMC) to assess the motor dysfunction in patients with Parkinson disease (PwPD) based on the MDS-UPDRSIII exerc...

    Authors: A. H. Butt, E. Rovini, C. Dolciotti, G. De Petris, P. Bongioanni, M. C. Carboncini and F. Cavallo

    Citation: BioMedical Engineering OnLine 2018 17:168

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  30. Content type: Correction

    After publication, it was highlighted that the original publication [1] contained a spelling mistake in the first name of Marcelo Gattas. This was incorrectly captured as Marelo Gattass in the original article...

    Authors: Alex M. Santos, Anselmo C. Paiva, Adriana P. M. Santos, Steve A. T. Mpinda, Daniel L. Gomes Jr., Aristófanes C. Silva, Geraldo Braz Jr., João Dallyson S. de Almeida and Marcelo Gattas

    Citation: BioMedical Engineering OnLine 2018 17:167

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    The original article was published in BioMedical Engineering OnLine 2018 17:160

  31. Content type: Research

    Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks ...

    Authors: Hye-Jeong Song, Byeong-Cheol Jo, Chan-Young Park, Jong-Dae Kim and Yu-Seop Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):158

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    This article is part of a Supplement: Volume 17 Supplement 2

  32. Content type: Research

    Pressure sensors have been used for sleeping posture detection, which meet privacy requirements. Most of the existing techniques for sleeping posture recognition used force-sensitive resistor (FSR) sensors. Ho...

    Authors: Rong-Shue Hsiao, Tian-Xiang Chen, Mekuanint Agegnehu Bitew, Chun-Hao Kao and Tzu-Yu Li

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):157

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  33. Content type: Research

    Polymerase chain reaction (PCR) is used in nucleic acid tests of infectious diseases in point-of-care testing. Previous studies have demonstrated real-time PCR that uses a micro-PCR chip made of packing tape, ...

    Authors: Ji-Soo Hwang, Jong-Dae Kim, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):156

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  34. Content type: Research

    One of the most important processes in a machine learning-based natural language processing is to represent words. The one-hot representation that has been commonly used has a large size of vector and assumes ...

    Authors: Hye-Jeong Song, Byeong-Hun Yoon, Young-Shin Youn, Chan-Young Park, Jong-Dae Kim and Yu-Seop Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):155

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  35. Content type: Research

    The significant advancement in the mobile sensing technologies has brought great interests on application development for the Internet-of-Things (IoT). With the advantages of contactlessness data retrieval and...

    Authors: Cheng-Fa Chiang, Fang-Ming Hsu and Kuo-Hui Yeh

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):154

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  36. Content type: Research

    In this paper, we propose a system for data monitoring and control of polymerase chain reaction (PCR) externally. PCR is a technique for amplifying a desired DNA molecule by repeatedly synthesizing a specific ...

    Authors: Jong-Dae Kim, So-Yeon Lee, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):153

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  37. Content type: Research

    Screening test using CA-125 is the most common test for detecting ovarian cancer. However, the level of CA-125 is diverse by variable condition other than ovarian cancer. It has led to misdiagnosis of ovarian ...

    Authors: Hye-Jeong Song, Eun-Suk Yang, Jong-Dae Kim, Chan-Young Park, Min-Sun Kyung and Yu-Seop Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):152

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  38. Content type: Research

    Intravascular ultrasound (IVUS) is a commonly used diagnostic imaging method for coronary artery disease. Virtual histology (VH) characterizes the plaque components into fibrous tissue (FT), fibro-fatty tissue...

    Authors: Ga Young Kim, Ju Hwan Lee, Yoo Na Hwang and Sung Min Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):151

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  39. Content type: Research

    In general, the image analysis of nucleic acid for detecting DNA is dependent on the gel documentation system. These experiments may deal with harmful staining agents and are time consuming. To address these i...

    Authors: Deuk-Ju Lee, Jong-Dae Kim, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):150

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  40. Content type: Research

    The purpose of this study was to investigate the efficacy of moxibustion therapy on weight loss, waist circumference and waist-to-hip ratio in young adult females. An experimental design, 51 Asian females were...

    Authors: Ching-Hsiu Hsieh, Chi-Chuan Tseng, Ju-Yu Shen and Pei-Ying Chuang

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):149

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  41. Content type: Research

    Dengue fever is a leading cause of severe illness and hospitalization in Taiwan. This study sought to elucidate the linkage between dengue fever incidence and climate factors.

    Authors: Yi-Horng Lai

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):148

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    This article is part of a Supplement: Volume 17 Supplement 2

  42. Content type: Review

    Biological and medical diagnoses depend on high-quality measurements. A wearable device based on Internet of Things (IoT) must be unobtrusive to the human body to encourage users to accept continuous monitorin...

    Authors: Wei-Hua Tang, Wen-Hsien Ho and Yenming J. Chen

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):147

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  43. Content type: Research

    This study estimates atrial repolarization activities (Ta waves), which are typically hidden most of the time from body surface electrocardiography when diagnosing cardiovascular diseases. The morphology of Ta wa...

    Authors: Wei-Hua Tang, Wen-Hsien Ho and Yenming J. Chen

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):146

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  44. Content type: Research

    In the past, manufacture of prosthetic socket by using traditional handmade method not only consumed research time but also required a special assembly approach. Recently, reverse engineering and rapid prototy...

    Authors: Cheung-Hwa Hsu, Chao-Hui Ou, Wei-Lun Hong and Yu-Han Gao

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):145

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  45. Content type: Research

    The accuracy and precision of liquid handling can be altered by several causes including wearing or failure of parts, and human error. The last cause is crucial since point-of-care testing (POCT) devices can b...

    Authors: Chan-Young Park, Jun Yeon, Hye-Jeong Song, Yu-Seop Kim, Ki-Bong Nahm and Jong-Dae Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):144

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  46. Content type: Research

    Recently, automatic molecular diagnostic devices to extract DNA have been extensively developed using magnetic beads. While various methods can be applied to the control of the beads, the efficiency of the con...

    Authors: Chang-Young Park, Young-Hyun Park, Yu-Seop Kim, Hye-Jeong Song and Jong-Dae Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):143

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  47. Content type: Research

    Discomfort evoked by stereoscopic depth has been widely concerned. Previous studies have proposed a comfortable disparity range and considered that disparities exceed this range would cause visual discomfort. ...

    Authors: Xiao Wang, Liuye Yao, Yuemei Zhao, Lidong Xing, Zhiyu Qian, Weitao Li and Yamin Yang

    Citation: BioMedical Engineering OnLine 2018 17:166

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  48. Content type: Research

    The anterior cruciate ligament (ACL) plays an important role in stabilizing translation and rotation of the tibia relative to the femur. ACL injury alters knee kinematics and usually links to the alternation o...

    Authors: Wenbao Wu, Wei Zeng, Limin Ma, Chengzhi Yuan and Yu Zhang

    Citation: BioMedical Engineering OnLine 2018 17:165

    Published on:

  49. Content type: Research

    The outermost layer of the tear film consists of a thin lipid layer (LL). The lipid layer serves as a barrier against evaporation of the aqueous component of the tear film. The ability to simultaneously image ...

    Authors: Yuqiang Bai, William Ngo, Boyu Gu, Yuhua Zhang and Jason J. Nichols

    Citation: BioMedical Engineering OnLine 2018 17:164

    Published on:

  50. Content type: Research

    Bubbles formed by acoustic droplet vaporization (ADV) have proven to be an effective method for significant enlargement of the thermal lesions produced by high intensity focused ultrasound (HIFU). We investiga...

    Authors: Ying Xin, Aili Zhang, Lisa X. Xu and J. Brian Fowlkes

    Citation: BioMedical Engineering OnLine 2018 17:163

    Published on:

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