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  1. Low-dose X-ray images have become increasingly popular in the last decades, due to the need to guarantee the lowest reasonable patient’s exposure. Dose reduction causes a substantial increase of quantum noise,...

    Authors: Emilio Andreozzi, Antonio Fratini, Daniele Esposito, Mario Cesarelli and Paolo Bifulco

    Citation: BioMedical Engineering OnLine 2021 20:36

    Content type: Research

    Published on:

  3. Coronary plaque vulnerability prediction is difficult because plaque vulnerability is non-trivial to quantify, clinically available medical image modality is not enough to quantify thin cap thickness, predicti...

    Authors: Xiaoya Guo, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Jie Zheng, Habib Samady, Gary S. Mintz, Don P. Giddens and Dalin Tang

    Citation: BioMedical Engineering OnLine 2021 20:34

    Content type: Research

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  4. MXene is a recently emerged multifaceted two-dimensional (2D) material that is made up of surface-modified carbide, providing its flexibility and variable composition. They consist of layers of early transitio...

    Authors: Adibah Zamhuri, Gim Pao Lim, Nyuk Ling Ma, Kian Sek Tee and Chin Fhong Soon

    Citation: BioMedical Engineering OnLine 2021 20:33

    Content type: Review

    Published on:

  5. Unified Parkinson Disease Rating Scale-part III (UPDRS III) is part of the standard clinical examination performed to track the severity of Parkinson’s disease (PD) motor complications. Wearable technologies c...

    Authors: Murtadha D. Hssayeni, Joohi Jimenez-Shahed, Michelle A. Burack and Behnaz Ghoraani

    Citation: BioMedical Engineering OnLine 2021 20:32

    Content type: Research

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  6. The use of machine learning (ML) methods would improve the diagnosis of respiratory changes in systemic sclerosis (SSc). This paper evaluates the performance of several ML algorithms associated with the respir...

    Authors: Domingos S. M. Andrade, Luigi Maciel Ribeiro, Agnaldo J. Lopes, Jorge L. M. Amaral and Pedro L. Melo

    Citation: BioMedical Engineering OnLine 2021 20:31

    Content type: Research

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  7. The regulation and control of pressure stimuli is useful for many studies of pain and nociception especially those in the visceral pain field. In many in vivo experiments, distinct air and liquid stimuli at va...

    Authors: Michael DeLong, Mauricio Gil-Silva, Veronica Minsu Hong, Olivia Babyok and Benedict J. Kolber

    Citation: BioMedical Engineering OnLine 2021 20:30

    Content type: Research

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  8. As an object’s electrical passive property, the electrical conductivity is proportional to the mobility and concentration of charged carriers that reflect the brain micro-structures. The measured multi-b diffusio...

    Authors: Mun Bae Lee, Hyung Joong Kim and Oh In Kwon

    Citation: BioMedical Engineering OnLine 2021 20:29

    Content type: Research

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  9. The structural changes of gastric mucosa are considered as an important window of early gastric lesions. This article shows an imaging method of the stomach that does not use imaging agents. X-ray phase-contra...

    Authors: Qiang Tao, Chenchen Gao, Xuehong Tong, Shizhen Yuan and Jingdong Xu

    Citation: BioMedical Engineering OnLine 2021 20:28

    Content type: Research

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  10. Lung ultrasound (LUS) can be an important imaging tool for the diagnosis and assessment of lung involvement. Ultrasound sonograms have been confirmed to illustrate damage to a person’s lungs, which means that ...

    Authors: Zhaoyu Hu, Zhenhua Liu, Yijie Dong, Jianjian Liu, Bin Huang, Aihua Liu, Jingjing Huang, Xujuan Pu, Xia Shi, Jinhua Yu, Yang Xiao, Hui Zhang and Jianqiao Zhou

    Citation: BioMedical Engineering OnLine 2021 20:27

    Content type: Research

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  11. Fresh stillbirths (FSB) and very early neonatal deaths (VEND) are important global challenges with 2.6 million deaths annually. The vast majority of these deaths occur in low- and low-middle income countries. ...

    Authors: Jarle Urdal, Kjersti Engan, Trygve Eftestøl, Solveig H. Haaland, Benjamin Kamala, Paschal Mdoe, Hussein Kidanto and Hege Ersdal

    Citation: BioMedical Engineering OnLine 2021 20:26

    Content type: Research

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  12. Electrical pulse stimulations have been applied in brain for treating certain diseases such as movement disorders. High-frequency stimulations (HFS) of biphasic pulses have been used in clinic stimulations, su...

    Authors: Yue Yuan, Lvpiao Zheng, Zhouyan Feng and Gangsheng Yang

    Citation: BioMedical Engineering OnLine 2021 20:25

    Content type: Research

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  13. Osteosarcoma (OS) is the most common primary bone malignancy that affects children and young adults. OS is characterized by a high degree of malignancy, strong invasiveness, rapid disease progression, and extr...

    Authors: Xin Zhao, Qirui Wu, Xiuqing Gong, Jinfeng Liu and Yujie Ma

    Citation: BioMedical Engineering OnLine 2021 20:24

    Content type: Review

    Published on:

  14. Precise visualization of meshes and their position would greatly aid in mesh shrinkage evaluation, hernia recurrence risk assessment, and the preoperative planning of salvage repair. Lightweight (LW) meshes ar...

    Authors: Jiting Yang, Haiyan Li, Jun Wu, Liang Sun, Dan Xu, Yuanyuan Wang, Yufeng Zhang, Yue Chen and Lin Chen

    Citation: BioMedical Engineering OnLine 2021 20:23

    Content type: Research

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  15. The detection and dissection of epidermal subgroups could lead to an improved understanding of skin homeostasis and wound healing. Flow cytometric analysis provides an effective method to detect the surface ma...

    Authors: Lidan Zhang, Ying Cen, Qiaorong Huang, Huifang Li, Xianming Mo, Wentong Meng and Junjie Chen

    Citation: BioMedical Engineering OnLine 2021 20:22

    Content type: Research

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  16. Over the last decades, microRNAs (miRNAs) have emerged as important molecules associated with the regulation of gene expression in humans and other organisms, expanding the strategies available to diagnose and...

    Authors: Leonardo J. Galvão-Lima, Antonio H. F. Morais, Ricardo A. M. Valentim and Elio J. S. S. Barreto

    Citation: BioMedical Engineering OnLine 2021 20:21

    Content type: Review

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  17. Self-esteem is the individual evaluation of oneself. People with high self-esteem grade have mental health and can bravely cope with the threats from the environment. With the development of neuroimaging techn...

    Authors: Bo Peng, Gaofeng Pang, Aditya Saxena, Yan Liu, Baohua Hu, Suhong Wang and Yakang Dai

    Citation: BioMedical Engineering OnLine 2021 20:20

    Content type: Research

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  18. Cone-shaped vena cava filters (VCFs) are widely used to treat venous thromboembolism. However, in the long term, the problem of occlusion persists even after the filter is deployed. A previous study hypothesiz...

    Authors: Ying Chen, Zaipin Xu, Xiaoyan Deng, Shibo Yang, Wenchang Tan, Yubo Fan, Yong Han and Yubin Xing

    Citation: BioMedical Engineering OnLine 2021 20:19

    Content type: Research

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  19. Advances in regenerative medicine technologies have been strongly proposed in the management of thyroid diseases. Mechanistically, the adoption of thyroid bioengineering requires a scaffold that shares a simil...

    Authors: Jie Weng, Bi Chen, Mengying Xie, Xinlong Wan, Peng Wang, Xiaoming Zhou, Zhiliang Zhou, Jin Mei, Liang Wang, Duping Huang, Zhibin Wang, Zhiyi Wang and Chan Chen

    Citation: BioMedical Engineering OnLine 2021 20:18

    Content type: Research

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  20. The tongue and hard palate play an essential role in the production of sound during continuous speech. Appropriate tongue and hard palate contacts will ensure proper sound production. Electropalatography, also...

    Authors: Syatirah Mat Zin, S. Z. Md Rasib, Fatanah M. Suhaimi and M. Mariatti

    Citation: BioMedical Engineering OnLine 2021 20:17

    Content type: Review

    Published on:

  21. Intravascular ultrasound (IVUS) is the golden standard in accessing the coronary lesions, stenosis, and atherosclerosis plaques. In this paper, a fully automatic approach by an 8-layer U-Net is developed to se...

    Authors: Liang Dong, Wenbing Jiang, Wei Lu, Jun Jiang, Ya Zhao, Xiangfen Song, Xiaochang Leng, Hang Zhao, Jian’an Wang, Changling Li and Jianping Xiang

    Citation: BioMedical Engineering OnLine 2021 20:16

    Content type: Research

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  22. The objective of the study was to validate biomechanical characteristics of a 3D-printed, novel-designated fixation plate for treating mandibular angle fracture, and compare it with two commonly used fixation ...

    Authors: Xu Xu, Kang-jie Cheng, Yun-feng Liu, Ying-ying Fan, Joanne H. Wang, Russell Wang, Dale A. Baur, Xian-feng Jiang and Xing-tao Dong

    Citation: BioMedical Engineering OnLine 2021 20:15

    Content type: Research

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  23. The lower extremities of the body often suffer from impaired microcirculation, particularly in the elderly or people with underlying conditions such as diabetes. Especially for people suffering from peripheral...

    Authors: Weiyan Ren, Liqiang Xu, Xuan Zheng, Fang Pu, Deyu Li and Yubo Fan

    Citation: BioMedical Engineering OnLine 2021 20:14

    Content type: Research

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  24. Recently, error-related negativity (ERN) signals are proposed to develop an assist-as-needed robotic stroke rehabilitation program. Stroke patients’ state-of-mind, such as motivation to participate and active ...

    Authors: Akshay Kumar, Qiang Fang and Elena Pirogova

    Citation: BioMedical Engineering OnLine 2021 20:13

    Content type: Research

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  25. Atrial fibrillation (AF) represents the most common arrhythmia worldwide, related to increased risk of ischemic stroke or systemic embolism. It is critical to screen and diagnose AF for the benefits of better ...

    Authors: Fangfang Jiang, Chuhang Hong, Tianqing Cheng, Haoqian Wang, Bowen Xu and Biyong Zhang

    Citation: BioMedical Engineering OnLine 2021 20:12

    Content type: Research

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  26. Multiple studies describing human head finite element (FE) models have established the importance of including the major cerebral vasculature to improve the accuracy of the model predictions. However, a more d...

    Authors: Dhananjay Radhakrishnan Subramaniam, Ginu Unnikrishnan, Aravind Sundaramurthy, Jose E. Rubio, Vivek Bhaskar Kote and Jaques Reifman

    Citation: BioMedical Engineering OnLine 2021 20:11

    Content type: Research

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  27. An electrical potential not previously reported—electrical cochlear response (ECR)—observed only in implanted patients is described. Its amplitude and growth slope are a measurement of the stimulation achieved...

    Authors: Juan M. Cornejo, Agar K. Quintana, Nohra E. Beltran and Pilar Granados

    Citation: BioMedical Engineering OnLine 2021 20:10

    Content type: Research

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  28. Patient-specific active fluid–structure interactions (FSI) model is a useful approach to non-invasively investigate the hemodynamics in the heart. However, it takes a lot of effort to obtain the proper externa...

    Authors: Xueying Huang, Long Deng, Heng Zuo, Chun Yang, Yunhu Song, Mary Lesperance and Dalin Tang

    Citation: BioMedical Engineering OnLine 2021 20:9

    Content type: Research

    Published on:

  29. Only a small fraction of the information available is generally used in the majority of camera-based sensing approaches for vital sign monitoring. Dedicated skin pixels, for example, fall into this category wh...

    Authors: Michael Paul, Sabrina Caprice Behr, Christoph Weiss, Konrad Heimann, Thorsten Orlikowsky and Steffen Leonhardt

    Citation: BioMedical Engineering OnLine 2021 20:8

    Content type: Research

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  30. The increased popularity of minimally invasive spinal surgery calls for a revision of guidance techniques to prevent injuries of nearby neural and vascular structures. Lipid content has previously been propose...

    Authors: Merle S. Losch, Akash Swamy, Adrian Elmi-Terander, Erik Edström, Benno H. W. Hendriks and Jenny Dankelman

    Citation: BioMedical Engineering OnLine 2021 20:7

    Content type: Research

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  31. Minimally invasive spine surgery is dependent on accurate navigation. Computer-assisted navigation is increasingly used in minimally invasive surgery (MIS), but current solutions require the use of reference m...

    Authors: Francesca Manni, Marco Mamprin, Ronald Holthuizen, Caifeng Shan, Gustav Burström, Adrian Elmi-Terander, Erik Edström, Svitlana Zinger and Peter H. N. de With

    Citation: BioMedical Engineering OnLine 2021 20:6

    Content type: Research

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  32. Novel endoscopic biophotonic diagnostic technologies have the potential to non-invasively detect the interior of a hollow organ or cavity of the human body with subcellular resolution or to obtain biochemical ...

    Authors: Zhongyu He, Peng Wang and Xuesong Ye

    Citation: BioMedical Engineering OnLine 2021 20:5

    Content type: Review

    Published on:

  33. The volume of the coagulation zones created during radiofrequency ablation (RFA) is limited by the appearance of roll-off. Doping the tissue with conductive fluids, e.g., gold nanoparticles (AuNPs) could enlar...

    Authors: Dora Luz Castro-López, Enrique Berjano and Ricardo Romero-Mendez

    Citation: BioMedical Engineering OnLine 2021 20:4

    Content type: Research

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  34. Kinocardiography (KCG) is a promising new technique used to monitor cardiac mechanical function remotely. KCG is based on ballistocardiography (BCG) and seismocardiography (SCG), and measures 12 degrees-of-fre...

    Authors: Amin Hossein, Jérémy Rabineau, Damien Gorlier, Farhana Pinki, Philippe van de Borne, Antoine Nonclercq and Pierre-François Migeotte

    Citation: BioMedical Engineering OnLine 2021 20:3

    Content type: Research

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  35. Use of standardized and scientifically sound outcome measures is encouraged in clinical practice and research. With the development of newer rehabilitation therapies, we need technology-supported upper extremi...

    Authors: Naaz Kapadia, Mathew Myers, Kristin Musselman, Rosalie H. Wang, Aaron Yurkewich and Milos R. Popovic

    Citation: BioMedical Engineering OnLine 2021 20:2

    Content type: Research

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  36. This research has proved that mechanomyographic (MMG) signals can be used for evaluating muscle performance. Stimulation of the lost physiological functions of a muscle using an electrical signal has been dete...

    Authors: Raphael Uwamahoro, Kenneth Sundaraj and Indra Devi Subramaniam

    Citation: BioMedical Engineering OnLine 2021 20:1

    Content type: Review

    Published on:

  37. Fractional-order (FrOr) models have a high potential to improve pulmonary science. These models could be useful for biomechanical studies and diagnostic purposes, offering accurate models with an improved abil...

    Authors: Fábio Augusto d´Alegria Tuza, Paula Morisco de Sá, Hermano A. Castro, Agnaldo José Lopes and Pedro Lopes de Melo

    Citation: BioMedical Engineering OnLine 2020 19:93

    Content type: Research

    Published on:

  38. Invasion depth is an important index for staging and clinical treatment strategy of bladder cancer (BCa). The aim of this study was to investigate the feasibility of segmenting the BCa region from bladder wall...

    Authors: Yang Liu, Haojie Zheng, Xiaopan Xu, Xi Zhang, Peng Du, Jimin Liang and Hongbing Lu

    Citation: BioMedical Engineering OnLine 2020 19:92

    Content type: Research

    Published on:

  40. Detecting coronary vulnerable plaques in vivo and assessing their vulnerability have been great challenges for clinicians and the research community. Intravascular ultrasound (IVUS) is commonly used in clinica...

    Authors: Rui Lv, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Qingyu Wang, Caining Zhang, Xiaoya Guo, Habib Samady, Don P. Giddens, Jie Zheng, Gary S. Mintz and Dalin Tang

    Citation: BioMedical Engineering OnLine 2020 19:90

    Content type: Research

    Published on:

  41. Anterior mediastinal cysts (AMC) are often misdiagnosed as thymomas and undergo surgical resection, which caused unnecessary treatment and medical resource waste. The purpose of this study is to explore potent...

    Authors: Lulu Liu, Fangxiao Lu, Peipei Pang and Guoliang Shao

    Citation: BioMedical Engineering OnLine 2020 19:89

    Content type: Research

    Published on:

  42. The large volume and suboptimal image quality of portable chest X-rays (CXRs) as a result of the COVID-19 pandemic could post significant challenges for radiologists and frontline physicians. Deep-learning art...

    Authors: Lal Hussain, Tony Nguyen, Haifang Li, Adeel A. Abbasi, Kashif J. Lone, Zirun Zhao, Mahnoor Zaib, Anne Chen and Tim Q. Duong

    Citation: BioMedical Engineering OnLine 2020 19:88

    Content type: Research

    Published on:

  43. Assessments of source reconstruction procedures in electroencephalography and computations of transcranial electrical stimulation profiles require verification and validation with the help of ground truth conf...

    Authors: Alexander Hunold, René Machts and Jens Haueisen

    Citation: BioMedical Engineering OnLine 2020 19:87

    Content type: Research

    Published on:

  44. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Henning Windhagen, Kerstin Radtke, Andreas Weizbauer, Julia Diekmann, Yvonne Noll, Ulrike Kreimeyer, Robert Schavan, Christina Stukenborg-Colsman and Hazibullah Waizy

    Citation: BioMedical Engineering OnLine 2020 19:86

    Content type: Correction

    Published on:

    The original article was published in BioMedical Engineering OnLine 2013 12:62

  45. The effectiveness of electrochemotherapy of tumors (ECT) and of irreversible electroporation ablation (IRE) depends on different mechanisms and delivery protocols. Both therapies exploit the phenomenon of elec...

    Authors: Tomaz Jarm, Tadej Krmac, Ratko Magjarevic, Bor Kos, Helena Cindric and Damijan Miklavcic

    Citation: BioMedical Engineering OnLine 2020 19:85

    Content type: Research

    Published on:

  46. The amount of propofol needed to induce loss of responsiveness varied widely among patients, and they usually required less than the initial dose recommended by the drug package inserts. Identifying precisely ...

    Authors: Ana Leitão Ferreira, Catarina S. Nunes, Sérgio Vide, João Felgueiras, Márcio Cardoso, Pedro Amorim and Joaquim Mendes

    Citation: BioMedical Engineering OnLine 2020 19:84

    Content type: Research

    Published on:

  47. As a serious clinical disease, ischemic stroke is usually detected through magnetic resonance imaging and computed tomography. In this study, a noninvasive, non-contact, real-time continuous monitoring system ...

    Authors: Shuang-Lin Zhao, Gui Jin, Ze-Lin Bai, Jing-Bo Chen, Meng-Wei Li, Gen Li, Wei Zhuang, Yue-Ning Liu and Ming-Xin Qin

    Citation: BioMedical Engineering OnLine 2020 19:83

    Content type: Research

    Published on:

  48. Instrumented pendulum test is an objective and repeatable biomechanical method of assessment for spasticity. However, multitude of sensor technologies and plenty of suggested outcome measures, confuse those in...

    Authors: Fariborz Rahimi, Reza Eyvazpour, Nazila Salahshour and Mahmood Reza Azghani

    Citation: BioMedical Engineering OnLine 2020 19:82

    Content type: Review

    Published on:

  49. Delivering short trains of electric pulses to the muscles and nerves can elicit action potentials resulting in muscle contractions. When the stimulations are sequenced to generate functional movements, such as...

    Authors: Matija Milosevic, Cesar Marquez-Chin, Kei Masani, Masayuki Hirata, Taishin Nomura, Milos R. Popovic and Kimitaka Nakazawa

    Citation: BioMedical Engineering OnLine 2020 19:81

    Content type: Review

    Published on:

  50. Healthcare studies are moving toward individualised measurement. There is need to move beyond supervised assessments in the laboratory/clinic. Longitudinal free-living assessment can provide a wealth of inform...

    Authors: G. Coulby, A. Clear, O. Jones, F. Young, S. Stuart and A. Godfrey

    Citation: BioMedical Engineering OnLine 2020 19:80

    Content type: Review

    Published on:

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BioMedical Engineering OnLine

ISSN: 1475-925X

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