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  1. Anterior mediastinal cysts (AMC) are often misdiagnosed as thymomas and undergo surgical resection, which caused unnecessary treatment and medical resource waste. The purpose of this study is to explore potent...

    Authors: Lulu Liu, Fangxiao Lu, Peipei Pang and Guoliang Shao

    Citation: BioMedical Engineering OnLine 2020 19:89

    Content type: Research

    Published on:

  2. The large volume and suboptimal image quality of portable chest X-rays (CXRs) as a result of the COVID-19 pandemic could post significant challenges for radiologists and frontline physicians. Deep-learning art...

    Authors: Lal Hussain, Tony Nguyen, Haifang Li, Adeel A. Abbasi, Kashif J. Lone, Zirun Zhao, Mahnoor Zaib, Anne Chen and Tim Q. Duong

    Citation: BioMedical Engineering OnLine 2020 19:88

    Content type: Research

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  3. Assessments of source reconstruction procedures in electroencephalography and computations of transcranial electrical stimulation profiles require verification and validation with the help of ground truth conf...

    Authors: Alexander Hunold, René Machts and Jens Haueisen

    Citation: BioMedical Engineering OnLine 2020 19:87

    Content type: Research

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  4. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Henning Windhagen, Kerstin Radtke, Andreas Weizbauer, Julia Diekmann, Yvonne Noll, Ulrike Kreimeyer, Robert Schavan, Christina Stukenborg-Colsman and Hazibullah Waizy

    Citation: BioMedical Engineering OnLine 2020 19:86

    Content type: Correction

    Published on:

    The original article was published in BioMedical Engineering OnLine 2013 12:62

  5. The effectiveness of electrochemotherapy of tumors (ECT) and of irreversible electroporation ablation (IRE) depends on different mechanisms and delivery protocols. Both therapies exploit the phenomenon of elec...

    Authors: Tomaz Jarm, Tadej Krmac, Ratko Magjarevic, Bor Kos, Helena Cindric and Damijan Miklavcic

    Citation: BioMedical Engineering OnLine 2020 19:85

    Content type: Research

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  6. The amount of propofol needed to induce loss of responsiveness varied widely among patients, and they usually required less than the initial dose recommended by the drug package inserts. Identifying precisely ...

    Authors: Ana Leitão Ferreira, Catarina S. Nunes, Sérgio Vide, João Felgueiras, Márcio Cardoso, Pedro Amorim and Joaquim Mendes

    Citation: BioMedical Engineering OnLine 2020 19:84

    Content type: Research

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  7. As a serious clinical disease, ischemic stroke is usually detected through magnetic resonance imaging and computed tomography. In this study, a noninvasive, non-contact, real-time continuous monitoring system ...

    Authors: Shuang-Lin Zhao, Gui Jin, Ze-Lin Bai, Jing-Bo Chen, Meng-Wei Li, Gen Li, Wei Zhuang, Yue-Ning Liu and Ming-Xin Qin

    Citation: BioMedical Engineering OnLine 2020 19:83

    Content type: Research

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  8. Instrumented pendulum test is an objective and repeatable biomechanical method of assessment for spasticity. However, multitude of sensor technologies and plenty of suggested outcome measures, confuse those in...

    Authors: Fariborz Rahimi, Reza Eyvazpour, Nazila Salahshour and Mahmood Reza Azghani

    Citation: BioMedical Engineering OnLine 2020 19:82

    Content type: Review

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  9. Delivering short trains of electric pulses to the muscles and nerves can elicit action potentials resulting in muscle contractions. When the stimulations are sequenced to generate functional movements, such as...

    Authors: Matija Milosevic, Cesar Marquez-Chin, Kei Masani, Masayuki Hirata, Taishin Nomura, Milos R. Popovic and Kimitaka Nakazawa

    Citation: BioMedical Engineering OnLine 2020 19:81

    Content type: Review

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  10. Healthcare studies are moving toward individualised measurement. There is need to move beyond supervised assessments in the laboratory/clinic. Longitudinal free-living assessment can provide a wealth of inform...

    Authors: G. Coulby, A. Clear, O. Jones, F. Young, S. Stuart and A. Godfrey

    Citation: BioMedical Engineering OnLine 2020 19:80

    Content type: Review

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  11. A bacterial biosensor refers to genetically engineered bacteria that produce an assessable signal in the presence of a physical or chemical agent in the environment.

    Authors: Esmail Nourmohammadi, Saman Hosseinkhani, Reza Nedaeinia, Hoda Khoshdel-Sarkarizi, Mozhdeh Nedaeinia, Maryam Ranjbar, Neshat Ebrahimi, Zahra Farjami, Mohammad Nourmohammadi, Ali Mahmoudi, Mohammad Goli, Gordon A. Ferns and Majid Sadeghizadeh

    Citation: BioMedical Engineering OnLine 2020 19:79

    Content type: Research

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  12. Screening for prediabetes and asymptomatic diabetes is important for preventing development to an irreversible stage. The current diagnosis of prediabetes and diabetes is based on blood glucose or HbA1c (an in...

    Authors: Xiaopeng Zhu, Jing Tang, Huandong Lin, Xinxia Chang, Mingfeng Xia, Liu Wang, Hongmei Yan, Hua Bian and Xin Gao

    Citation: BioMedical Engineering OnLine 2020 19:78

    Content type: Research

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  13. Esophageal thermal injury can occur after radiofrequency (RF) ablation in the left atrium to treat atrial fibrillation. Existing methods to prevent esophageal injury have various limitations in deployment and ...

    Authors: Marcela Mercado, Lisa Leung, Mark Gallagher, Shailee Shah and Erik Kulstad

    Citation: BioMedical Engineering OnLine 2020 19:77

    Content type: Research

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  14. Three-dimensional (3D) printing is widely used in medicine. Most research remains focused on forming rigid anatomical models, but moving from static models to dynamic functionality could greatly aid preoperati...

    Authors: Hao Wang, Hongning Song, Yuanting Yang, Quan Cao, Yugang Hu, Jinling Chen, Juan Guo, Yijia Wang, Dan Jia, Sheng Cao and Qing Zhou

    Citation: BioMedical Engineering OnLine 2020 19:76

    Content type: Review

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  15. The world is facing an unprecedented outbreak affecting all aspects of human lives which is caused by the COVID-19 pandemic. Due to the virus novelty, healthcare systems are challenged by a high rate of patien...

    Authors: Almir Badnjević, Lejla Gurbeta Pokvić, Zijad Džemić and Fahir Bečić

    Citation: BioMedical Engineering OnLine 2020 19:75

    Content type: Commentary

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  16. There is a need to promote recovery after stroke with novel therapeutic interventions. Of them, bone-marrow mononuclear cell (BM-MNC) therapy offers promising outcomes in preclinical and clinical models.

    Authors: Sorayouth Chumnanvej and Siriluk Chumnanvej

    Citation: BioMedical Engineering OnLine 2020 19:74

    Content type: Research

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  17. Intracranial aneurysm is a common type of cerebrovascular disease with a risk of devastating subarachnoid hemorrhage if it is ruptured. Accurate computer-aided detection of aneurysms can help doctors improve t...

    Authors: Tao Hu, Heng Yang, Wei Ni, Yu Lei, Zhuoyun Jiang, Keke Shi, Jinhua Yu, Yuxiang Gu and Yuanyuan Wang

    Citation: BioMedical Engineering OnLine 2020 19:73

    Content type: Research

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  18. Numerous sensing techniques have been investigated in an effort to monitor the main parameters influencing the residual limb/prosthesis interface, fundamental to the optimum design of prosthetic socket solutio...

    Authors: Linda Paternò, Vimal Dhokia, Arianna Menciassi, James Bilzon and Elena Seminati

    Citation: BioMedical Engineering OnLine 2020 19:71

    Content type: Research

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  19. Alzheimer’s Disease (AD) is a degenerative brain disorder that often occurs in people over 65 years old. As advanced AD is difficult to manage, accurate diagnosis of the disorder is critical. Previous studies ...

    Authors: Han Woong Kim, Ha Eun Lee, KyeongTaek Oh, Sangwon Lee, Mijin Yun and Sun K. Yoo

    Citation: BioMedical Engineering OnLine 2020 19:70

    Content type: Research

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  20. Advances in biomaterials and the need for patient-specific bone scaffolds require modern manufacturing approaches in addition to a design strategy. Hybrid materials such as those with functionally graded prope...

    Authors: Marjan Bahraminasab

    Citation: BioMedical Engineering OnLine 2020 19:69

    Content type: Review

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  21. Increasing evidence has demonstrated the correlation between hepatocellular carcinoma (HCC) prognosis and RNA binding proteins (RBPs) dysregulation. Thus, we aimed to develop and validate a reliable prognostic...

    Authors: Chunmiao Kang, Xuanhui Jia and Hongsheng Liu

    Citation: BioMedical Engineering OnLine 2020 19:68

    Content type: Research

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  22. Balance control deteriorates with age and nearly 30% of the elderly population in the United States reports stability problems. Postural stability is an integral task to daily living reliant upon the control o...

    Authors: Angel Cerda-Lugo, Alejandro González, Antonio Cardenas and Davide Piovesan

    Citation: BioMedical Engineering OnLine 2020 19:67

    Content type: Research

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  23. Chest CT screening as supplementary means is crucial in diagnosing novel coronavirus pneumonia (COVID-19) with high sensitivity and popularity. Machine learning was adept in discovering intricate structures fr...

    Authors: Chenglong Liu, Xiaoyang Wang, Chenbin Liu, Qingfeng Sun and Wenxian Peng

    Citation: BioMedical Engineering OnLine 2020 19:66

    Content type: Research

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  24. The progressive evolution in hip replacement research is directed to follow the principles of bone and soft tissue sparing surgery. Regarding hip implants, a renewed interest has been raised towards short unce...

    Authors: I. Tatani, P. Megas, A. Panagopoulos, I. Diamantakos, Ph. Nanopoulos and Sp. Pantelakis

    Citation: BioMedical Engineering OnLine 2020 19:65

    Content type: Research

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  25. Fear of falling (FoF) is defined as a lasting concern about falling that causes a person to limit or even stop the daily activities that he/she is capable of. Seventy percent of Parkinson’s disease (PD) patien...

    Authors: Ehsan Pourghayoomi, Saeed Behzadipour, Mehdi Ramezani, Mohammad Taghi Joghataei and Gholam Ali Shahidi

    Citation: BioMedical Engineering OnLine 2020 19:64

    Content type: Research

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  26. Chest CT is used for the assessment of the severity of patients infected with novel coronavirus 2019 (COVID-19). We collected chest CT scans of 202 patients diagnosed with the COVID-19, and try to develop a ra...

    Authors: Zekuan Yu, Xiaohu Li, Haitao Sun, Jian Wang, Tongtong Zhao, Hongyi Chen, Yichuan Ma, Shujin Zhu and Zongyu Xie

    Citation: BioMedical Engineering OnLine 2020 19:63

    Content type: Research

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  27. Alveolar cleft is a type of cleft lip and palate that seriously affects the physical and mental health of patients. In this study, a model of the alveolar cleft phenotype was established in rabbits to evaluate...

    Authors: Xue-Cheng Sun, Hu Wang, Jian-hui Li, Dan Zhang, Li-Qiang Yin, Yu-Fang Yan, Xu Ma and Hong-Fei Xia

    Citation: BioMedical Engineering OnLine 2020 19:62

    Content type: Research

    Published on:

  28. Nonnegative matrix factorization (NMF) has been successfully used for electroencephalography (EEG) spectral analysis. Since NMF was proposed in the 1990s, many adaptive algorithms have been developed. However,...

    Authors: Guoqiang Hu, Tianyi Zhou, Siwen Luo, Reza Mahini, Jing Xu, Yi Chang and Fengyu Cong

    Citation: BioMedical Engineering OnLine 2020 19:61

    Content type: Research

    Published on:

  29. General anesthesia can affect intestinal function, but there is no objective, practical and effective indicator to evaluate the inhibition and recovery of intestinal function. The main objectives of this study...

    Authors: Guojing Wang, Mingjun Wang, Hongyun Liu, Suping Zhao, Lu Liu and Weidong Wang

    Citation: BioMedical Engineering OnLine 2020 19:60

    Content type: Research

    Published on:

  30. The anomalous origin of the right coronary artery (RCA) from the left coronary artery sinus (AORL) is one of the abnormal origins of the coronary arteries. Most of these issues rarely have any effects on human...

    Authors: Mengyang Cong, Xingming Xu, Jianfeng Qiu, Shun Dai, Chuanzhi Chen, Xiuqing Qian, Hongbin Zhang, Shengxue Qin and Huihui Zhao

    Citation: BioMedical Engineering OnLine 2020 19:59

    Content type: Research

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  31. Machine learning models were satisfactorily implemented for estimating gait events from surface electromyographic (sEMG) signals during walking. Most of them are based on inter-subject approaches for data prep...

    Authors: Francesco Di Nardo, Christian Morbidoni, Guido Mascia, Federica Verdini and Sandro Fioretti

    Citation: BioMedical Engineering OnLine 2020 19:58

    Content type: Research

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  32. Inertial measurement unit (IMU)-based motion capture systems are gaining popularity for gait analysis outside laboratories. It is important to determine the performance of such systems in specific patient popu...

    Authors: Karina Berner, John Cockcroft and Quinette Louw

    Citation: BioMedical Engineering OnLine 2020 19:57

    Content type: Research

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  33. To reproduce anatomical reduction and appropriate implant placement/choices during osteosynthesis for elbow fractures, we developed a 3D preoperative planning system. To assess the utility of 3D digital preope...

    Authors: Yuichi Yoshii, Shin Teramura, Kazuki Oyama, Takeshi Ogawa, Yuki Hara and Tomoo Ishii

    Citation: BioMedical Engineering OnLine 2020 19:56

    Content type: Research

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  34. Three-dimensional (3D) printing is a promising technology, but the limitations are often poorly understood. We compare different 3D printing methods with conventional machining techniques in manufacturing meat...

    Authors: Michael Y. Chen, Jacob Skewes, Ryan Daley, Maria A. Woodruff and Nicholas J. Rukin

    Citation: BioMedical Engineering OnLine 2020 19:55

    Content type: Research

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  35. The objective of the study is to investigate the effect of catheter type and injection method on microsphere distributions, specifically vessel targeting accuracy.

    Authors: Shaphan R. Jernigan, Jason A. Osborne and Gregory D. Buckner

    Citation: BioMedical Engineering OnLine 2020 19:54

    Content type: Research

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  36. Anorexia nervosa is a clinical disorder syndrome of the wide spectrum without a fully recognized etiology. The necessary issue in the clinical diagnostic process is to detect the causes of this disease (e.g., ...

    Authors: Dominik Spinczyk, Mateusz Bas, Mariusz Dzieciątko, Michał Maćkowski, Katarzyna Rojewska and Stella Maćkowska

    Citation: BioMedical Engineering OnLine 2020 19:53

    Content type: Research

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  37. Colorectal cancer is the third leading cause of cancer-related deaths worldwide. Sonodynamic therapy (SDT) is an emerging cancer therapy, and in contrast to photodynamic therapy, could non-invasively reach dee...

    Authors: Yuanyuan Shen, Jianquan Ou, Xin Chen, Xiaojun Zeng, Lanhui Huang, Zhaoke Pi, Yaxin Hu, Siping Chen and Tie Chen

    Citation: BioMedical Engineering OnLine 2020 19:52

    Content type: Research

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  38. Image segmentation is an important part of computer-aided diagnosis (CAD), the segmentation of small ground glass opacity (GGO) pulmonary nodules is beneficial for the early detection of lung cancer. For the s...

    Authors: Shaorong Zhang, Xiangmeng Chen, Zhibin Zhu, Bao Feng, Yehang Chen and Wansheng Long

    Citation: BioMedical Engineering OnLine 2020 19:51

    Content type: Research

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  39. Advances in transcranial electrical stimulation (tES) are hampered by the conventional rubber electrodes manually attached to the head with rubber bands. This procedure limits montages to a few electrodes, is ...

    Authors: Alexander Hunold, Daniela Ortega, Klaus Schellhorn and Jens Haueisen

    Citation: BioMedical Engineering OnLine 2020 19:50

    Content type: Research

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  40. Heartbeat interval Lorenz plot (LP) imaging is a promising method for detecting atrial fibrillation (AF) in long-term monitoring, but the optimal segment window length for the LP images is unknown. We examined...

    Authors: Masaya Kisohara, Yuto Masuda, Emi Yuda, Norihiro Ueda and Junichiro Hayano

    Citation: BioMedical Engineering OnLine 2020 19:49

    Content type: Research

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  41. The development of wearable health monitoring systems is garnering tremendous interest in research, technology and commercial applications. Their ability of providing unique capabilities in continuous, real-ti...

    Authors: Milad Alizadeh Meghrazi, Yupeng Tian, Amin Mahnam, Presish Bhattachan, Ladan Eskandarian, Sara Taghizadeh Kakhki, Milos R. Popovic and Milad Lankarany

    Citation: BioMedical Engineering OnLine 2020 19:48

    Content type: Research

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  42. The safe and accurate placement of pedicle screws remains a critical step in open and minimally invasive spine surgery, emphasizing the need for intraoperative guidance techniques. Diffuse reflectance spectros...

    Authors: Akash Swamy, Jarich W. Spliethoff, Gustav Burström, Drazenko Babic, Christian Reich, Joanneke Groen, Erik Edström, Adrian Elmi-Terander, John M. Racadio, Jenny Dankelman and Benno H. W. Hendriks

    Citation: BioMedical Engineering OnLine 2020 19:47

    Content type: Research

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  43. Neurofeedback aids volitional control of one’s own brain activity using non-invasive recordings of brain activity. The applications of neurofeedback include improvement of cognitive performance and treatment o...

    Authors: Kunjan D. Rana, Sheraz Khan, Matti S. Hämäläinen and Lucia M. Vaina

    Citation: BioMedical Engineering OnLine 2020 19:45

    Content type: Research

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  44. Restenosis remains a challenge in the treatment of atherosclerosis due to damage to the endothelial layer and induced proliferation of smooth muscle cells. A novel radiofrequency (RF) heating strategy was prop...

    Authors: Shiqing Zhao, Jincheng Zou, Hongying Wang, Jinbao Qin, Xinwu Lu, Aili Zhang and Lisa X. Xu

    Citation: BioMedical Engineering OnLine 2020 19:44

    Content type: Research

    Published on:

  45. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Wei Hou, Xianting Zhu, Juan Liu and Jiaguo Ma

    Citation: BioMedical Engineering OnLine 2020 19:43

    Content type: Correction

    Published on:

    The original article was published in BioMedical Engineering OnLine 2020 19:15

  46. Diffusion MRI is the preferred non-invasive in vivo modality for the study of brain white matter connections. Tractography datasets contain 3D streamlines that can be analyzed to study the main brain white mat...

    Authors: Andrea Vázquez, Narciso López-López, Josselin Houenou, Cyril Poupon, Jean-François Mangin, Susana Ladra and Pamela Guevara

    Citation: BioMedical Engineering OnLine 2020 19:42

    Content type: Research

    Published on:

  47. Skull stripping remains a challenge for neonatal brain MR image analysis. However, little is known about the accuracy of how skull stripping affects the neonatal brain tissue segmentation and subsequent networ...

    Authors: Geliang Wang, Yajie Hu, Xianjun Li, Miaomiao Wang, Congcong Liu, Jian Yang and Chao Jin

    Citation: BioMedical Engineering OnLine 2020 19:41

    Content type: Research

    Published on:

  48. As the rupture of cerebral aneurysm may lead to fatal results, early detection of unruptured aneurysms may save lives. At present, the contrast-unenhanced time-of-flight magnetic resonance angiography is one o...

    Authors: Geng Chen, Xia Wei, Huang Lei, Yang Liqin, Li Yuxin, Dai Yakang and Geng Daoying

    Citation: BioMedical Engineering OnLine 2020 19:38

    Content type: Research

    Published on: