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  1. The escalating impact of diabetes and its complications, including diabetic foot ulcers (DFUs), presents global challenges in quality of life, economics, and resources, affecting around half a billion people. ...

    Authors: Reza Basiri, Karim Manji, Philip M. LeLievre, John Toole, Faith Kim, Shehroz S. Khan and Milos R. Popovic
    Citation: BioMedical Engineering OnLine 2024 23:12
  2. Functional electrical stimulation (FES) can be used in rehabilitation to aid or improve function in people with paralysis. In clinical settings, it is common practice to use transcutaneous electrodes to apply ...

    Authors: Melissa Marquez-Chin, Zia Saadatnia, Yu-Chen Sun, Hani E. Naguib and Milos R. Popovic
    Citation: BioMedical Engineering OnLine 2024 23:10
  3. Pulse wave, as a message carrier in the cardiovascular system (CVS), enables inferring CVS conditions while diagnosing cardiovascular diseases (CVDs). Heart failure (HF) is a major CVD, typically requiring exp...

    Authors: Sirui Wang, Ryohei Ono, Dandan Wu, Kaoruko Aoki, Hirotoshi Kato, Togo Iwahana, Sho Okada, Yoshio Kobayashi and Hao Liu
    Citation: BioMedical Engineering OnLine 2024 23:7
  4. Breast fibroadenoma poses a significant health concern, particularly for young women. Computer-aided diagnosis has emerged as an effective and efficient method for the early and accurate detection of various s...

    Authors: Yongxin Guo, Maoshan Chen, Lei Yang, Heng Yin, Hongwei Yang and Yufeng Zhou
    Citation: BioMedical Engineering OnLine 2024 23:5
  5. In this study, an automatic corneal contour extraction algorithm with a shared model is developed to extract contours from dynamic corneal videos containing noise, which improves the accuracy of corneal biomec...

    Authors: Zuoping Tan, Xuan Chen, Qiang Xu, Can Yang, Xiaomin Lin, Yan Huo, Mohammad Alzogool, Riwei Wang and Yan Wang
    Citation: BioMedical Engineering OnLine 2024 23:4
  6. Bioelectric signals, whether exogenous or endogenous, play crucial roles in the life processes of organisms. Recently, the significance of bioelectricity in the field of dentistry is steadily gaining greater a...

    Authors: Qingqing Min, Yajun Gao and Yao Wang
    Citation: BioMedical Engineering OnLine 2024 23:3
  7. Balance parameters derived from wearable sensor measurements during postural sway have been shown to be sensitive to experimental variables such as test duration, sensor number, and sensor location that influe...

    Authors: Vahid Abdollah, Alireza Noamani, John Ralston, Chester Ho and Hossein Rouhani
    Citation: BioMedical Engineering OnLine 2024 23:2
  8. Stroke necessitates interventions to rehabilitate individuals with disabilities, and the application of functional electrical stimulation therapy (FEST) has demonstrated potential in this regard. This study ai...

    Authors: Wagner Rodrigues Galvão, Luana Karoline Castro Silva, Magno Ferreira Formiga, George André Pereira Thé, Christina Danielli Coelho de Morais Faria, Ramon Távora Viana and Lidiane Andréa Oliveira Lima
    Citation: BioMedical Engineering OnLine 2024 23:1
  9. Haemorrhage transformation (HT) is a serious complication of intravenous thrombolysis (IVT) in acute ischaemic stroke (AIS). Accurate and timely prediction of the risk of HT before IVT may change the treatment...

    Authors: Xiaoshuang Ru, Shilong Zhao, Weidao Chen, Jiangfen Wu, Ruize Yu, Dawei Wang, Mengxing Dong, Qiong Wu, Daoyong Peng and Yang Song
    Citation: BioMedical Engineering OnLine 2023 22:129
  10. RAGE is a multiligand receptor for the immunoglobulin superfamily of cell surface molecules and is expressed in Müller cells, vascular endothelial cells, nerve cells and RPE cells of the retina. Diabetic retin...

    Authors: ZhiWen Lu, Bin Fan, YunZhi Li and YiXin Zhang
    Citation: BioMedical Engineering OnLine 2023 22:128
  11. Atherosclerosis is one of the most frequent cardiovascular diseases. The dilemma faced by physicians is whether to treat or postpone the revascularization of lesions that fall within the intermediate range giv...

    Authors: Irina-Andra Tache, Cosmin-Andrei Hatfaludi, Andrei Puiu, Lucian Mihai Itu, Nicoleta-Monica Popa-Fotea, Lucian Calmac and Alexandru Scafa-Udriste
    Citation: BioMedical Engineering OnLine 2023 22:127
  12. Artificial intelligence (AI) has shown excellent diagnostic performance in detecting various complex problems related to many areas of healthcare including ophthalmology. AI diagnostic systems developed from f...

    Authors: Xiaoqin Huang, Md Rafiqul Islam, Shanjita Akter, Fuad Ahmed, Ehsan Kazami, Hashem Abu Serhan, Alaa Abd-alrazaq and Siamak Yousefi
    Citation: BioMedical Engineering OnLine 2023 22:126
  13. Multi-omics research has the potential to holistically capture intra-tumor variability, thereby improving therapeutic decisions by incorporating the key principles of precision medicine. The purpose of this st...

    Authors: Eleftherios Trivizakis, Nikoletta-Maria Koutroumpa, John Souglakos, Apostolos Karantanas, Michalis Zervakis and Kostas Marias
    Citation: BioMedical Engineering OnLine 2023 22:125
  14. Wireless capsule endoscopy (WCE) is a patient-friendly and non-invasive technology that scans the whole of the gastrointestinal tract, including difficult-to-access regions like the small bowel. Major drawback...

    Authors: Mehrdokht Bordbar, Mohammad Sadegh Helfroush, Habibollah Danyali and Fardad Ejtehadi
    Citation: BioMedical Engineering OnLine 2023 22:124
  15. Prediction of non-perfusion volume ratio (NPVR) is critical in selecting patients with uterine fibroids who will potentially benefit from ultrasound-guided high-intensity focused ultrasound (HIFU) treatment, a...

    Authors: Ye Zhou, Jinwei Zhang, Chenghai Li, Jinyun Chen, Fajin Lv, Yongbin Deng, Siyao Chen, Yuling Du and Faqi Li
    Citation: BioMedical Engineering OnLine 2023 22:123
  16. Gait model consists of a marker set and a segment pose estimation algorithm. Plugin marker set and inverse kinematic algorithm (IK.) are prevalent in gait analysis, especially musculoskeletal motion analysis. ...

    Authors: Run Ji, Wayne Yuk-wai Lee, Xinyu Guan, Bin Yan, Lei Yang, Jiemeng Yang, Ling Wang, Chunjing Tao, Shengzheng Kuai and Yubo Fan
    Citation: BioMedical Engineering OnLine 2023 22:122
  17. The efficacy of vibration therapy (VT) in people with post-stroke spasticity (PSS) remains uncertain. This study aims to conduct a comprehensive meta-analysis to assess the effectiveness of VT in PSS.

    Authors: Duchun Zeng, Wei Lei, Yurou Kong, Fenghao Ma, Kun Zhao, Xiangming Ye and Tongcai Tan
    Citation: BioMedical Engineering OnLine 2023 22:121
  18. Gait impairments in Parkinson’s disease (PD) are treated with dopaminergic medication or deep-brain stimulation (DBS), although the magnitude of the response is variable between individuals. Computer vision-ba...

    Authors: Andrea Sabo, Andrea Iaboni, Babak Taati, Alfonso Fasano and Carolina Gorodetsky
    Citation: BioMedical Engineering OnLine 2023 22:120
  19. Shigella flexneri (S. flexneri) is a common intestinal pathogenic bacteria that mainly causes bacillary dysentery, especially in low socioeconomic countries. This study aimed to apply cold atmospheric plasma (CAP...

    Authors: Yan Chen, Yuanyuan He, Tao Jin, Chenwei Dai, Qinghua Xu and Zhengwei Wu
    Citation: BioMedical Engineering OnLine 2023 22:119
  20. It is difficult to create intuitive methods of controlling prosthetic limbs, often resulting in abandonment. Peripheral nerve interfaces can be used to convert motor intent into commands to a prosthesis. The E...

    Authors: Taseen Jawad, Ryan G. L. Koh and José Zariffa
    Citation: BioMedical Engineering OnLine 2023 22:118
  21. Chest computed tomography (CT) image quality impacts radiologists’ diagnoses. Pre-diagnostic image quality assessment is essential but labor-intensive and may have human limitations (fatigue, perceptual biases...

    Authors: Jialin Su, Meifang Li, Yongping Lin, Liu Xiong, Caixing Yuan, Zhimin Zhou and Kunlong Yan
    Citation: BioMedical Engineering OnLine 2023 22:117
  22. In-hospital cardiac arrest (IHCA) is an acute disease with a high fatality rate that burdens individuals, society, and the economy. This study aimed to develop a machine learning (ML) model using routine labor...

    Authors: Xinhuan Ding, Yingchan Wang, Weiyi Ma, Yaojun Peng, Jingjing Huang, Meng Wang and Haiyan Zhu
    Citation: BioMedical Engineering OnLine 2023 22:116
  23. Undiagnosed and untreated lung pathologies are among the leading causes of neonatal deaths in developing countries. Lung Ultrasound (LUS) has been widely accepted as a diagnostic tool for neonatal lung patholo...

    Authors: Sagarjit Aujla, Adel Mohamed, Ryan Tan, Karl Magtibay, Randy Tan, Lei Gao, Naimul Khan and Karthikeyan Umapathy
    Citation: BioMedical Engineering OnLine 2023 22:115
  24. This systematic review and meta-analysis were conducted to objectively evaluate the evidence of machine learning (ML) in the patient diagnosis of Intracranial Hemorrhage (ICH) on computed tomography (CT) scans.

    Authors: Masoud Maghami, Shahab Aldin Sattari, Marziyeh Tahmasbi, Pegah Panahi, Javad Mozafari and Kiarash Shirbandi
    Citation: BioMedical Engineering OnLine 2023 22:114
  25. Understanding the hemodynamics of an abdominal aortic aneurysm (AAA) is crucial for risk assessment and treatment planning. This study introduces a low-cost, patient-specific in vitro AAA model to investigate ...

    Authors: Can Özcan, Özgür Kocatürk, Civan Işlak and Cengizhan Öztürk
    Citation: BioMedical Engineering OnLine 2023 22:113
  26. To develop a comprehensive multi-classification model that combines radiomics and clinic-radiological features to accurately predict the invasiveness and differentiation of pulmonary adenocarcinoma nodules.

    Authors: Haitao Sun, Chunling Zhang, Aimei Ouyang, Zhengjun Dai, Peiji Song and Jian Yao
    Citation: BioMedical Engineering OnLine 2023 22:112
  27. The aim of this study was to investigate the generalization performance of deep learning segmentation models on a large cohort intravascular ultrasound (IVUS) image dataset over the lumen and external elastic ...

    Authors: Liang Dong, Wei Lu, Xuzhou Lu, Xiaochang Leng, Jianping Xiang and Changling Li
    Citation: BioMedical Engineering OnLine 2023 22:111
  28. The Gross Motor Function Classification System (GMFCS) is a widely used tool for assessing the mobility of people with Cerebral Palsy (CP). It classifies patients into different levels based on their gross mot...

    Authors: Changwon Yoon, Yongho Jeon, Hosik Choi, Soon-Sun Kwon and Jeongyoun Ahn
    Citation: BioMedical Engineering OnLine 2023 22:109
  29. Freezing-of-gait (FOG) and impaired walking are common features of Parkinson’s disease (PD). Provision of external stimuli (cueing) can improve gait, however, many cueing methods are simplistic, increase task ...

    Authors: Dongli Li, Andre Hallack, Sophie Gwilym, Dongcheng Li, Michele T. Hu and James Cantley
    Citation: BioMedical Engineering OnLine 2023 22:108
  30. Fractures are the most common orthopedic diseases. It is known that static magnetic fields (SMFs) can contribute to the maintenance of bone health. However, the effect and mechanism of SMFs on fracture is stil...

    Authors: Shenghang Wang, Yuetong Liu, Chenge Lou, Chao Cai, Weihao Ren, Junyu Liu, Ming Gong, Peng Shang and Hao Zhang
    Citation: BioMedical Engineering OnLine 2023 22:107
  31. The morphology of the adrenal tumor and the clinical statistics of the adrenal tumor area are two crucial diagnostic and differential diagnostic features, indicating precise tumor segmentation is essential. Th...

    Authors: Liping Wang, Mingtao Ye, Yanjie Lu, Qicang Qiu, Zhongfeng Niu, Hengfeng Shi and Jian Wang
    Citation: BioMedical Engineering OnLine 2023 22:106
  32. The contouring of organs at risk (OARs) in head and neck cancer radiation treatment planning is a crucial, yet repetitive and time-consuming process. Recent studies have applied deep learning (DL) algorithms t...

    Authors: Peiru Liu, Ying Sun, Xinzhuo Zhao and Ying Yan
    Citation: BioMedical Engineering OnLine 2023 22:104
  33. To classify early endometrial cancer (EC) on sagittal T2-weighted images (T2WI) by determining the depth of myometrial infiltration (MI) using a computer-aided diagnosis (CAD) method based on a multi-stage dee...

    Authors: Liu Xiong, Chunxia Chen, Yongping Lin, Wei Mao and Zhiyu Song
    Citation: BioMedical Engineering OnLine 2023 22:103
  34. Patient–ventilator asynchrony is common during mechanical ventilation (MV) in intensive care unit (ICU), leading to worse MV care outcome. Identification of asynchrony is critical for optimizing MV settings to...

    Authors: Yuhong Chen, Kun Zhang, Cong Zhou, J. Geoffrey Chase and Zhenjie Hu
    Citation: BioMedical Engineering OnLine 2023 22:102
  35. Myocardial bridges are congenital anatomical abnormalities in which myocardium covers a segment of coronary arteries, leading to stenocardia, myocardial ischemia, and sudden cardiac death in severe cases. Howe...

    Authors: Peng Zhou, Guangpu Wang, Shuo Wang, Huanming Li, Chong Liu, Jinglai Sun and Hui Yu
    Citation: BioMedical Engineering OnLine 2023 22:101
  36. Cerebral microbleeds (CMBs) serve as neuroimaging biomarkers to assess risk of intracerebral hemorrhage and diagnose cerebral small vessel disease (CSVD). Therefore, detecting CMBs can evaluate the risk of int...

    Authors: Ruizhen Wu, Huaqing Liu, Hao Li, Lifen Chen, Lei Wei, Xuehong Huang, Xu Liu, Xuejiao Men, Xidan Li, Lanqing Han, Zhengqi Lu and Bing Qin
    Citation: BioMedical Engineering OnLine 2023 22:99
  37. During the aging process, cognitive functions and performance of the muscular and neural system show signs of decline, thus making the elderly more susceptible to disease and death. These alterations, which oc...

    Authors: Veronica de Lima Gonçalves, Caio Tonus Ribeiro, Guilherme Lopes Cavalheiro, Maria José Ferreira Zaruz, Daniel Hilário da Silva, Selma Terezinha Milagre, Adriano de Oliveira Andrade and Adriano Alves Pereira
    Citation: BioMedical Engineering OnLine 2023 22:98
  38. Studies evaluating the effectiveness and safety of telerehabilitation in patients undergoing total knee arthroplasty (TKA) have increased. However, the study quality and results differ, systematic reviews are ...

    Authors: Danli Pang, Aiping Sun, Fei Wang, Jingyu Lu, Yaorui Guo and Wen Ding
    Citation: BioMedical Engineering OnLine 2023 22:97
  39. Transformers have been widely used in many computer vision challenges and have shown the capability of producing better results than convolutional neural networks (CNNs). Taking advantage of capturing long-ran...

    Authors: Chukwuemeka Clinton Atabansi, Jing Nie, Haijun Liu, Qianqian Song, Lingfeng Yan and Xichuan Zhou
    Citation: BioMedical Engineering OnLine 2023 22:96
  40. While lumbar spinal fusion using rigid rods is a prevalent surgical technique, it can lead to complications such as adjacent segment disease (ASDis). Dynamic stabilization devices serve to maintain physiologic...

    Authors: Jianbin Guan, Tao Liu, Xing Yu, Wenhao Li, Ningning Feng, Guozheng Jiang, He Zhao and Yongdong Yang
    Citation: BioMedical Engineering OnLine 2023 22:95
  41. Eight commercially available percutaneous transluminal coronary angioplasty (PTCA), including semi-compliant and non-compliant balloons, have been assessed in detail on their tip, balloon, shaft, RX-Port, and ...

    Authors: C. Amstutz, J. Behr, S. Krebs, A. Haeberlin, R. Vogel, A. Zurbuchen and J. Burger
    Citation: BioMedical Engineering OnLine 2023 22:94