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  1. Diabetic retinopathy (DR) is an eye disease that causes blindness and vision loss in diabetic. Risk factors for DR include high blood glucose levels and some environmental factors. The pathogenesis is based on...

    Authors: Bin Li, Wahab Hussain, Zhi-Liang Jiang, Jia-Yi Wang, Sarfraz Hussain, Talat Bilal Yasoob, Yuan-Kun Zhai, Xin-Ying Ji and Ya-Long Dang
    Citation: BioMedical Engineering OnLine 2024 23:62
  2. Left ventricular enlargement (LVE) is a common manifestation of cardiac remodeling that is closely associated with cardiac dysfunction, heart failure (HF), and arrhythmias. This study aimed to propose a machin...

    Authors: Dandan Wu, Ryohei Ono, Sirui Wang, Yoshio Kobayashi, Koichi Sughimoto and Hao Liu
    Citation: BioMedical Engineering OnLine 2024 23:60
  3. The subjective sign of a serious pandemic in human work and life is mathematical neural tinnitus. fNIRS (functional near-infrared spectroscopy) is a new non-invasive brain imaging technology for studying the n...

    Authors: Xiaoli Fan, Bin Gong, Hao Yang, Juanjuan Yang, Gaowei Qi, Zheng Wang, Jie Sun and Yu Fang
    Citation: BioMedical Engineering OnLine 2024 23:59
  4. Heart rate variability (HRV) may provide objective information about cardiogenic autonomic balance in individuals with spinal cord injury (SCI). The aim of this study was to characterize the diurnal variation ...

    Authors: Jittima Saengsuwan, Arphatsorn Ruangsuphaphichat, Lars Brockmann, Patpiya Sirasaporn, Nuttaset Manimmanakorn and Kenneth J. Hunt
    Citation: BioMedical Engineering OnLine 2024 23:58
  5. Our objective was to create a machine learning architecture capable of identifying obstructive sleep apnea (OSA) patterns in single-lead electrocardiography (ECG) signals, exhibiting exceptional performance wh...

    Authors: Meng-Hsuan Liu, Shang-Yu Chien, Ya-Lun Wu, Ting-Hsuan Sun, Chun-Sen Huang, Kai-Cheng Hsu and Liang-Wen Hang
    Citation: BioMedical Engineering OnLine 2024 23:57
  6. This study was designed to explore and validate the value of different machine learning models based on ultrasound image-omics features in the preoperative diagnosis of lymph node metastasis in pancreatic canc...

    Authors: Dong-yue Wen, Jia-min Chen, Zhi-ping Tang, Jin-shu Pang, Qiong Qin, Lu Zhang, Yun He and Hong Yang
    Citation: BioMedical Engineering OnLine 2024 23:56
  7. Schizophrenia (SZ), a psychiatric disorder for which there is no precise diagnosis, has had a serious impact on the quality of human life and social activities for many years. Therefore, an advanced approach f...

    Authors: Xinyi Xu, Geng Zhu, Bin Li, Ping Lin, Xiaoou Li and Zhen Wang
    Citation: BioMedical Engineering OnLine 2024 23:55
  8. During the transtibial posterior cruciate ligament (PCL) reconstruction, drilling depth excessively longer than the tibial tunnel length (TTL) is an important reason to cause popliteal neurovascular bundle inj...

    Authors: Gengxin Jia, Xiaoyang Jia, Minfei Qiang, Tianhao Shi, Qinghui Han and Yanxi Chen
    Citation: BioMedical Engineering OnLine 2024 23:54
  9. Metastasis is one of the main factors leading to the high mortality rate of gastric cancer. The current monitoring methods are not able to accurately monitor gastric cancer metastasis.

    Authors: Zhihua Yang, Chenying Wang, Shangting Du, Qin Ma, Wei Wang, Changhu liu, Yonghua Zhan and Wenhua Zhan
    Citation: BioMedical Engineering OnLine 2024 23:53
  10. Accurate segmentation of multiple organs in the head, neck, chest, and abdomen from medical images is an essential step in computer-aided diagnosis, surgical navigation, and radiation therapy. In the past few ...

    Authors: Xiaoyu Liu, Linhao Qu, Ziyue Xie, Jiayue Zhao, Yonghong Shi and Zhijian Song
    Citation: BioMedical Engineering OnLine 2024 23:52
  11. Functional electrical stimulation (FES) is a rehabilitation technique that enables functional improvements in patients with motor control impairments. This study presents an original design and prototyping met...

    Authors: Baptiste Garnier, Melissa Marquez-Chin, Stephanie DiNunzio, Stephanie N. Iwasa, Zia Saadatnia, Hani E. Naguib and Milos R. Popovic
    Citation: BioMedical Engineering OnLine 2024 23:51
  12. Over 60% of epilepsy patients globally are children, whose early diagnosis and treatment are critical for their development and can substantially reduce the disease’s burden on both families and society. Numer...

    Authors: Leen Huang, Keying Zhou, Siyang Chen, Yanzhao Chen and Jinxin Zhang
    Citation: BioMedical Engineering OnLine 2024 23:50
  13. Monitoring of ingestive activities is critically important for managing the health and wellness of individuals with various health conditions, including the elderly, diabetics, and individuals seeking better w...

    Authors: Eman A. Hassan, Yassin Khalifa and Ahmed A. Morsy
    Citation: BioMedical Engineering OnLine 2024 23:48
  14. Electrotransfection is based on application of high-voltage pulses that transiently increase membrane permeability, which enables delivery of DNA and RNA in vitro and in vivo. Its advantage in applications suc...

    Authors: Mojca Pavlin, Nives Škorja Milić, Maša Kandušer and Sergej Pirkmajer
    Citation: BioMedical Engineering OnLine 2024 23:47
  15. Integration of a patient’s non-invasive imaging data in a digital twin (DT) of the heart can provide valuable insight into the myocardial disease substrates underlying left ventricular (LV) mechanical discoord...

    Authors: Tijmen Koopsen, Nick van Osta, Tim van Loon, Roel Meiburg, Wouter Huberts, Ahmed S. Beela, Feddo P. Kirkels, Bas R. van Klarenbosch, Arco J. Teske, Maarten J. Cramer, Geertruida P. Bijvoet, Antonius van Stipdonk, Kevin Vernooy, Tammo Delhaas and Joost Lumens
    Citation: BioMedical Engineering OnLine 2024 23:46
  16. Sleep-disordered breathing (SDB) affects a significant portion of the population. As such, there is a need for accessible and affordable assessment methods for diagnosis but also case-finding and long-term fol...

    Authors: Jiali Xie, Pedro Fonseca, Johannes van Dijk, Sebastiaan Overeem and Xi Long
    Citation: BioMedical Engineering OnLine 2024 23:45
  17. Osteocytes are critical mechanosensory cells in bone, and mechanically stimulated osteocytes produce exosomes that can induce osteogenesis. MicroRNAs (miRNAs) are important constituents of exosomes, and some m...

    Authors: Yingwen Zhu, Yanan Li, Zhen Cao, Jindong Xue, Xiaoyan Wang, Tingting Hu, Biao Han and Yong Guo
    Citation: BioMedical Engineering OnLine 2024 23:44
  18. We developed a video-based tool to quantitatively assess the Glabellar Tap Reflex (GTR) in patients with idiopathic Parkinson’s disease (iPD) as well as healthy age-matched participants. We also video-graphica...

    Authors: Talisa S. Jansen, Gökhan Güney, Bergita Ganse, Mariana H. G. Monje, Jörg B. Schulz, Manuel Dafotakis, Christoph Hoog Antink and Anne K. Braczynski
    Citation: BioMedical Engineering OnLine 2024 23:43
  19. Computed tomography (CT) is an imaging modality commonly used for studies of internal body structures and very useful for detailed studies of body composition. The aim of this study was to develop and evaluate...

    Authors: Nouman Ahmad, Hugo Dahlberg, Hanna Jönsson, Sambit Tarai, Rama Krishna Guggilla, Robin Strand, Elin Lundström, Göran Bergström, Håkan Ahlström and Joel Kullberg
    Citation: BioMedical Engineering OnLine 2024 23:42
  20. The timely identification and management of ovarian cancer are critical determinants of patient prognosis. In this study, we developed and validated a deep learning radiomics nomogram (DLR_Nomogram) based on u...

    Authors: Yangchun Du, Yanju Xiao, Wenwen Guo, Jinxiu Yao, Tongliu Lan, Sijin Li, Huoyue Wen, Wenying Zhu, Guangling He, Hongyu Zheng and Haining Chen
    Citation: BioMedical Engineering OnLine 2024 23:41
  21. Congenital heart disease (CHD) is one of the most common birth defects in the world. It is the leading cause of infant mortality, necessitating an early diagnosis for timely intervention. Prenatal screening us...

    Authors: Laifa Yan, Shan Ling, Rongsong Mao, Haoran Xi and Fei Wang
    Citation: BioMedical Engineering OnLine 2024 23:39
  22. After stroke, restoring safe, independent, and efficient walking is a top rehabilitation priority. However, in nearly 70% of stroke survivors asymmetrical walking patterns and reduced walking speed persist. Th...

    Authors: Yaejin Moon, Chen Yang, Nicole C. Veit, Kelly A. McKenzie, Jay Kim, Shreya Aalla, Lindsey Yingling, Kristine Buchler, Jasmine Hunt, Sophia Jenz, Sung Yul Shin, Ameen Kishta, V. Reggie Edgerton, Yury P. Gerasimenko, Elliot J. Roth, Richard L. Lieber…
    Citation: BioMedical Engineering OnLine 2024 23:38
  23. The diagnostic test for vasovagal syncope (VVS), the most common cause of syncope is head-up tilt test (HUTT) assessment. During the test, subjects experienced clinical symptoms such as nausea, sweating, pallo...

    Authors: Mahbuba Ferdowsi, Ban-Hoe Kwan, Maw Pin Tan, Nor’ Izzati Saedon, Sukanya Subramaniam, Noor Fatin Izzati Abu Hashim, Siti Sakinah Mohd Nasir, Imran Zainal Abidin, Kok Han Chee and Choon-Hian Goh
    Citation: BioMedical Engineering OnLine 2024 23:37
  24. The reduced treatment time of dental implants with immediate loading protocol is an appealing solution for dentists and patients. However, there remains a significant risk of early peri-implant bone response f...

    Authors: Chuanyuan Mao, Weijun Yu, Guanglong Li, Ziyuan Xu, Yuhua Gong, Min Jin and Eryi Lu
    Citation: BioMedical Engineering OnLine 2024 23:36
  25. Tele-rehabilitation is the provision of physiotherapy services to individuals in their own homes. Activity recognition plays a crucial role in the realm of automatic tele-rehabilitation. By assessing patient m...

    Authors: Alireza Ettefagh and Atena Roshan Fekr
    Citation: BioMedical Engineering OnLine 2024 23:35
  26. Decubitus ulcers are prevalent among the aging population due to a gradual decline in their overall health, such as nutrition, mental health, and mobility, resulting in injury to the skin and tissue. The most ...

    Authors: Lindsay Stern, Geoff Fernie and Atena Roshan Fekr
    Citation: BioMedical Engineering OnLine 2024 23:34
  27. This study aimed to investigate the imaging repeatability of self-service fundus photography compared to traditional fundus photography performed by experienced operators.

    Authors: Juzhao Zhang, Xuan Luo, Deshang Li, Yajun Peng, Guiling Gao, Liangwen Lei, Meng Gao, Lina Lu, Yi Xu, Tao Yu, Senlin Lin, Yingyan Ma, Chunxia Yao and Haidong Zou
    Citation: BioMedical Engineering OnLine 2024 23:32
  28. Ultrasound three-dimensional visualization, a cutting-edge technology in medical imaging, enhances diagnostic accuracy by providing a more comprehensive and readable portrayal of anatomical structures compared...

    Authors: Junyu Mi, Rui Wang, Qian Feng, Lin Han, Yan Zhuang, Ke Chen, Zhong Chen, Zhan Hua, Yan luo and Jiangli Lin
    Citation: BioMedical Engineering OnLine 2024 23:31
  29. Critically ill patients undergoing liberation often encounter various physiological and clinical complexities and challenges. However, whether the combination of hyperbaric oxygen and in-cabin ventilator thera...

    Authors: Yinliang Qi, Jixiang Xu, Hui Liu and Xiaomei Zhou
    Citation: BioMedical Engineering OnLine 2024 23:30
  30. To explore the predictive value of bedside lung ultrasound score in the severity of neonatal respiratory distress syndrome (NRDS) and mechanical ventilation and extubation.

    Authors: Peipei Huang, Deng Chen, Xiuxiang Liu, Xiang Zhang and Xiazi Song
    Citation: BioMedical Engineering OnLine 2024 23:29
  31. Persons with asthma may experience excessive airway narrowing due to exercise or exposure to cold air, worsening their daily functionality. Exercise has several benefits for asthma control, but it may induce a...

    Authors: Shaghayegh Chavoshian, Xiaoshu Cao, Anirudh Thommandram, Matthew B. Stanbrook, Susan M. Tarlo, Yan Fossat and Azadeh Yadollahi
    Citation: BioMedical Engineering OnLine 2024 23:28
  32. Deep Self-Attention Network (Transformer) is an encoder–decoder architectural model that excels in establishing long-distance dependencies and is first applied in natural language processing. Due to its comple...

    Authors: Yuwei Yin, Zhixian Tang and Huachun Weng
    Citation: BioMedical Engineering OnLine 2024 23:27
  33. Flash glucose monitoring systems like the FreeStyle Libre (FSL) sensor have gained popularity for monitoring glucose levels in people with diabetes mellitus. This sensor can be paired with an off-label convert...

    Authors: Jhon E. Goez-Mora, Natalia Arbeláez-Córdoba, Norman Balcazar-Morales and Pablo S. Rivadeneira
    Citation: BioMedical Engineering OnLine 2024 23:26
  34. The accurate detection of eyelid tumors is essential for effective treatment, but it can be challenging due to small and unevenly distributed lesions surrounded by irrelevant noise. Moreover, early symptoms of...

    Authors: Jiewei Jiang, Haiyang Liu, Lang He, Mengjie Pei, Tongtong Lin, Hailong Yang, Junhua Yang, Jiamin Gong, Xumeng Wei, Mingmin Zhu, Guohai Wu and Zhongwen Li
    Citation: BioMedical Engineering OnLine 2024 23:25
  35. Aortic stenosis, hypertension, and left ventricular hypertrophy often coexist in the elderly, causing a detrimental mismatch in coupling between the heart and vasculature known as ventricular−vascular (VA) cou...

    Authors: Corina Cheng Ai Ding, Socrates Dokos, Azam Ahmad Bakir, Nurul Jannah Zamberi, Yih Miin Liew, Bee Ting Chan, Nor Ashikin Md Sari, Alberto Avolio and Einly Lim
    Citation: BioMedical Engineering OnLine 2024 23:24
  36. Non-invasive, beat-to-beat variations in physiological indices provide an opportunity for more accessible assessment of autonomic dysfunction. The potential association between the changes in these parameters ...

    Authors: Jia Hui Ooi, Renly Lim, Hansun Seng, Maw Pin Tan, Choon Hian Goh, Nigel H. Lovell, Ahmadreza Argha, Hooi Chin Beh, Nor Ashikin Md Sari and Einly Lim
    Citation: BioMedical Engineering OnLine 2024 23:23
  37. Adolescent idiopathic scoliosis (AIS), three-dimensional spine deformation, affects body motion. Previous research had indicated pathological gait patterns of AIS. However, the impact of the curve number on th...

    Authors: Run Ji, Xiaona Liu, Yang Liu, Bin Yan, Jiemeng Yang, Wayne Yuk-wai Lee, Ling Wang, Chunjing Tao, Shengzheng Kuai and Yubo Fan
    Citation: BioMedical Engineering OnLine 2024 23:22
  38. Human activity Recognition (HAR) using smartphone sensors suffers from two major problems: sensor orientation and placement. Sensor orientation and sensor placement problems refer to the variation in sensor si...

    Authors: Arnab Barua, Xianta Jiang and Daniel Fuller
    Citation: BioMedical Engineering OnLine 2024 23:21
  39. Human–robot walking with prosthetic legs and exoskeletons, especially over complex terrains, such as stairs, remains a significant challenge. Egocentric vision has the unique potential to detect the walking en...

    Authors: Andrew Garrett Kurbis, Dmytro Kuzmenko, Bogdan Ivanyuk-Skulskiy, Alex Mihailidis and Brokoslaw Laschowski
    Citation: BioMedical Engineering OnLine 2024 23:20
  40. Individuals with incomplete spinal-cord injury/disease are at an increased risk of falling due to their impaired ability to maintain balance. Our research group has developed a closed-loop visual-feedback bala...

    Authors: Derrick Lim, William Pei, Jae W. Lee, Kristin E. Musselman and Kei Masani
    Citation: BioMedical Engineering OnLine 2024 23:19
  41. The research gap addressed in this study is the applicability of deep neural network (NN) models on wearable sensor data to recognize different activities performed by patients with Parkinson’s Disease (PwPD) ...

    Authors: Shelly Davidashvilly, Maria Cardei, Murtadha Hssayeni, Christopher Chi and Behnaz Ghoraani
    Citation: BioMedical Engineering OnLine 2024 23:17
  42. Previous studies have reported that abnormal interlimb coordination is a typical characteristic of motor developmental delay (MDD) during human movement, which can be visually manifested as abnormal motor post...

    Authors: Li Zhang, Chong Xu, Lin Chen, Yuan Liu, Nong Xiao, Xiaoying Wu, Yuxia Chen and Wensheng Hou
    Citation: BioMedical Engineering OnLine 2024 23:16
  43. Automatic speech assessments have the potential to dramatically improve ALS clinical practice and facilitate patient stratification for ALS clinical trials. Acoustic speech analysis has demonstrated the abilit...

    Authors: Leif E. R. Simmatis, Jessica Robin, Michael J. Spilka and Yana Yunusova
    Citation: BioMedical Engineering OnLine 2024 23:15
  44. Turning in place is a challenging motor task and is used as a brief assessment test of lower limb function and dynamic balance. This review aims to examine how research of instrumented analysis of turning in p...

    Authors: Slavka Netukova, Lucie Horakova, Zoltan Szabo and Radim Krupicka
    Citation: BioMedical Engineering OnLine 2024 23:13