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  1. With the spread of COVID-19, telemedicine has played an important role, but tele-auscultation is still unavailable in most countries. This study introduces and tests a tele-auscultation system (Stemoscope) and...

    Authors: Muge Fan, Qiuli Wang, Jiaqi Liu, Lingyun Su, Bingjian Wang, Hai Xu, Qing Li and Zhi Zhang
    Citation: BioMedical Engineering OnLine 2022 21:63
  2. Aerosols and droplets are the transmission routes of many respiratory infectious diseases. The COVID-19 management guidance recommends against the use of nebulized inhalation therapy directly in the emergency ...

    Authors: Chen-Hsun Weng, Chia-Lung Kao, Po-Wei Chiu, Shao-Peng Huang, Yuh-Shin Kuo, Yu-Yuan Lin, I-Chen Lin, Hung-Chieh Chang, Chien-Hsin Lu and Chih-Hao Lin
    Citation: BioMedical Engineering OnLine 2022 21:62
  3. The age-related changes of gait symmetry in healthy children concerning individual joint and muscle activation data have previously been widely studied. Extending beyond individual joints or muscles, identifyi...

    Authors: Qiliang Xiong, Jinliang Wan, Shaofeng Jiang and Yuan Liu
    Citation: BioMedical Engineering OnLine 2022 21:61
  4. Remarkable work has been recently introduced to enhance the usage of Electromyography (EMG) signals in operating prosthetic arms. Despite the rapid advancements in this field, providing a reliable, naturalisti...

    Authors: Hend ElMohandes, Seif Eldawlatly, Josep Marcel Cardona Audí, Roman Ruff and Klaus-Peter Hoffmann
    Citation: BioMedical Engineering OnLine 2022 21:60
  5. Recently, transcatheter aortic valve replacement (TAVR) has been suggested as a less invasive treatment compared to surgical aortic valve replacement, for patients with severe aortic stenosis. Despite the atte...

    Authors: Paris Xenofontos, Reza Zamani and Mohammad Akrami
    Citation: BioMedical Engineering OnLine 2022 21:59
  6. Motor cortex stimulation applied as a clinical treatment for neuropathic disorders for decades. With stimulation electrodes placed directly on the cortical surface, this neuromodulation method provides higher ...

    Authors: Long Liu, Jiacheng Zhang, Jie Sun and Kedi Xu
    Citation: BioMedical Engineering OnLine 2022 21:58

    The Correction to this article has been published in BioMedical Engineering OnLine 2022 21:72

  7. Cardiac damage is the leading cause of death in uremic patients. This study aimed to evaluate the application of non-invasive myocardial work index (NIMWI) by echocardiography in assessing the left ventricular...

    Authors: Huizhen Zhu, Yanan Li, Cunying Cui, Danqing Huang, Yuanyuan Liu, Ruijie Liu, Qingqing Zhao, Ying Wang and Lin Liu
    Citation: BioMedical Engineering OnLine 2022 21:57
  8. Flat feet increase the risk of knee osteoarthritis and contribute to frailty, which may lead to worse life prognoses. The influence of the foot skeletal structure on flat feet is not yet entirely understood. F...

    Authors: Tomoko Yamashita, Kazuhiko Yamashita, Mitsuru Sato, Masashi Kawasumi and Shingo Ata
    Citation: BioMedical Engineering OnLine 2022 21:56
  9. Refractive error detection is a significant factor in preventing the development of myopia. To improve the efficiency and accuracy of refractive error detection, a refractive error detection network (REDNet) i...

    Authors: Daoliang Xu, Shangshang Ding, Tianli Zheng, Xingshuai Zhu, Zhiheng Gu, Bin Ye and Weiwei Fu
    Citation: BioMedical Engineering OnLine 2022 21:55
  10. CPT-11 (irinotecan) is one of the most efficient agents used for colorectal cancer chemotherapy. However, as for many other chemotherapeutic drugs, how to minimize the side effects of CPT-11 still needs to be ...

    Authors: Yongwei Liu, Xinghui Li, Renqun Pen, Wei Zuo, Ya Chen, Xiuying Sun, Juhua Gou, Qianwen Guo, Maoling Wen, Wuqi Li, Shuangjiang Yu, Hao Liu and Min Huang
    Citation: BioMedical Engineering OnLine 2022 21:53
  11. Diffusion-weighted (DW) imaging is a well-recognized magnetic resonance imaging (MRI) technique that is being routinely used in brain examinations in modern clinical radiology practices. This study focuses on ...

    Authors: Sahan M. Vijithananda, Mohan L. Jayatilake, Badra Hewavithana, Teresa Gonçalves, Luis M. Rato, Bimali S. Weerakoon, Tharindu D. Kalupahana, Anil D. Silva and Karuna D. Dissanayake
    Citation: BioMedical Engineering OnLine 2022 21:52
  12. Brain-controlled wheelchairs (BCWs) are important applications of brain–computer interfaces (BCIs). Currently, most BCWs are semiautomatic. When users want to reach a target of interest in their immediate envi...

    Authors: Kaixuan Liu, Yang Yu, Yadong Liu, Jingsheng Tang, Xinbin Liang, Xingxing Chu and Zongtan Zhou
    Citation: BioMedical Engineering OnLine 2022 21:50
  13. Ocular diseases are closely related to the physiological changes in the eye sphere and its contents. Using biomechanical methods to explore the relationship between the structure and function of ocular tissue ...

    Authors: Yali Zhao, Guohuang Hu, Yuwei Yan, Zhen Wang, Xiaohua Liu and Huanhuan Shi
    Citation: BioMedical Engineering OnLine 2022 21:49
  14. Authors: Chiang-Wen Lee, Ming-Hsien Chiang, Wen-Chun Wei, Shu-Hsien Liao, Yen-Bin Liu, Kuan-Chih Huang, Kuen-Lin Chen, Wen-Cheng Kuo, Yuan-Ching Sung, Ting-Yuan Chen, Ju-Fang Liu, Yao-Chang Chiang, Hsin-Nung Shih, Kuo-Ti Peng and Jen-Jie Chieh
    Citation: BioMedical Engineering OnLine 2022 21:48

    The original article was published in BioMedical Engineering OnLine 2022 21:38

  15. To assess the feasibility and clinical utility of artificial intelligence (AI)-based screening for diabetic retinopathy (DR) and macular edema (ME) by combining fundus photos and optical coherence tomography (...

    Authors: Rui Liu, Qingchen Li, Feiping Xu, Shasha Wang, Jie He, Yiting Cao, Fei Shi, Xinjian Chen and Jili Chen
    Citation: BioMedical Engineering OnLine 2022 21:47
  16. Advances in sports medicine, rehabilitation applications and diagnostics of neuromuscular disorders are based on the analysis of skeletal muscle contractions. Recently, medical imaging techniques have transfor...

    Authors: Hazrat Ali, Johannes Umander, Robin Rohlén, Oliver Röhrle and Christer Grönlund
    Citation: BioMedical Engineering OnLine 2022 21:46
  17. Abnormal prolongation in the QT interval or long QT syndrome (LQTS) is associated with several cardiac complications such as sudden infant death syndrome (SIDS). LQTS is believed to be linked to genetic mutati...

    Authors: Namareq Widatalla, Kiyoe Funamoto, Motoyoshi Kawataki, Chihiro Yoshida, Kenichi Funamoto, Masatoshi Saito, Yoshiyuki Kasahara, Ahsan Khandoker and Yoshitaka Kimura
    Citation: BioMedical Engineering OnLine 2022 21:45
  18. Dysautonomia plays an ancillary role in the pathogenesis of Chronic Chagas Cardiomyopathy (CCC), but is the key factor causing digestive organic involvement. We investigated the ability of heart rate variabili...

    Authors: Luiz Eduardo Virgilio Silva, Henrique Turin Moreira, Marina Madureira de Oliveira, Lorena Sayore Suzumura Cintra, Helio Cesar Salgado, Rubens Fazan Jr, Renato Tinós, Anis Rassi Jr, André Schmidt and J. Antônio Marin-Neto
    Citation: BioMedical Engineering OnLine 2022 21:44
  19. Cutaneous electrogastrography (EGG) is a non-invasive technique that detects gastric bioelectrical slow waves, which in part govern the motility of the stomach. Changes in gastric slow waves have been associat...

    Authors: Atchariya Sukasem, Stefan Calder, Timothy R. Angeli-Gordon, Christopher N. Andrews, Gregory O’Grady, Armen Gharibans and Peng Du
    Citation: BioMedical Engineering OnLine 2022 21:43
  20. It is known that inflammatory bowel disease is the result of a defective immune system, and immunotherapy and biological therapy have gradually become important means to treat it. This paper focused on the bib...

    Authors: Jia-Qi Xiong, Yun-Feng Fu, Jian-Hao Qiu, Wang-Di Liao, Ling-Yu Luo and Si-Hai Chen
    Citation: BioMedical Engineering OnLine 2022 21:42
  21. Considering the estimate that thyroid cancer will become the fourth most prevalent type of tumor, improving its diagnosis is a necessity. The gold standard for evaluating thyroid nodules is ultrasound followed...

    Authors: Viviane Magas Bittencourt de Camargo, Leandra Ulbricht, Jose Carlos Pereira Coninck, Wagner Luis Ripka and Humberto Remigio Gamba
    Citation: BioMedical Engineering OnLine 2022 21:41
  22. The minimum variance (MV) beamformer can significantly improve the image resolution in ultrasound imaging, but it has limited performance in noise reduction. We recently proposed the covariance matrix-based st...

    Authors: Yuanguo Wang, Yadan Wang, Mingzhou Liu, Zhengfeng Lan, Chichao Zheng and Hu Peng
    Citation: BioMedical Engineering OnLine 2022 21:40
  23. Hypertension is known as a major factor for global mortality. We aimed to investigate the role of Cullin3 (CUL3) in the regulation of hypertension.

    Authors: Jian Shen, Youqi Li, Menghao Li, Zhiming Li, Huantang Deng, Xiongwei Xie and Jinguang Liu
    Citation: BioMedical Engineering OnLine 2022 21:39
  24. Although the powerful clinical effects of radiofrequency and microwave ablation have been established, such ablation is associated with several limitations, including a small ablation size, a long ablation tim...

    Authors: Chiang-Wen Lee, Ming-Hsien Chiang, Wen-Chun Wei, Shu-Hsien Liao, Yen-Bin Liu, Kuan-Chih Huang, Kuen-Lin Chen, Wen-Cheng Kuo, Yuan-Ching Sung, Ting-Yuan Chen, Ju-Fang Liu, Yao-Chang Chiang, Hsin-Nung Shih, Kuo-Ti Peng and Jen-Jie Chieh
    Citation: BioMedical Engineering OnLine 2022 21:38

    The Correction to this article has been published in BioMedical Engineering OnLine 2022 21:48

  25. Near-infrared (NIR) autofluorescence detection is an effective method for identifying parathyroid glands (PGs) in thyroidectomy or parathyroidectomy. Fiber optical probes provide quantitative autofluorescence ...

    Authors: Wei Chen, Xiaopeng Ma, Pengfei Shao, Peng Liu and Ronald X. Xu
    Citation: BioMedical Engineering OnLine 2022 21:37
  26. Despite numerous clinical trials and pre-clinical developments, the diagnosis of cracked tooth, especially in the early stages, remains a challenge. Cracked tooth syndrome is often accompanied by dramatic pain...

    Authors: Juncheng Guo, Yuyan Wu, Lizhi Chen, Shangbin Long, Daqi Chen, Haibing Ouyang, Chunliang Zhang, Yadong Tang and Wenlong Wang
    Citation: BioMedical Engineering OnLine 2022 21:36
  27. Low- to high-energy impact trauma may cause from small fissures up to extended bone losses, which can be classified as closed or opened injuries (when they are visible at a naked eye).

    Authors: Wally auf der Strasse, Daniel Prado Campos, Celso Júnio Aguiar Mendonça, Jamil Faissal Soni, Joaquim Mendes and Percy Nohama
    Citation: BioMedical Engineering OnLine 2022 21:35
  28. There are a variety of internal fixation methods for unstable femoral neck fractures (FNFs), but the best method is still unclear. Femoral neck system (FNS) is a dynamic angular stabilization system with cross...

    Authors: Zheng Wang, Yong Yang, Gangning Feng, Haohui Guo, Zhirong Chen, Yaogeng Chen and Qunhua Jin
    Citation: BioMedical Engineering OnLine 2022 21:34
  29. Machine learning, especially deep learning, is becoming more and more relevant in research and development in the medical domain. For all the supervised deep learning applications, data is the most critical fa...

    Authors: Adrian Krenzer, Kevin Makowski, Amar Hekalo, Daniel Fitting, Joel Troya, Wolfram G. Zoller, Alexander Hann and Frank Puppe
    Citation: BioMedical Engineering OnLine 2022 21:33
  30. The current method to evaluate the autonomic balance after renal denervation (RDN) relies on heart rate variability (HRV). However, parameters of HRV were not always predictive of response to RDN. Therefore, t...

    Authors: Po-Lin Lin, Ping-Yen Lin, Han-Ping Huang, Hamideh Vaezi, Lawrence Yu-Min Liu, Ying-Hsiang Lee, Chun-Che Huang, Ten-Fang Yang, Long Hsu and Chang Francis Hsu
    Citation: BioMedical Engineering OnLine 2022 21:32
  31. The objective is to clarify the effect of alveolar cleft bone graft on maxillofacial biomechanical stabilities, the key areas when bone grafting and in which should be supplemented with bone graft once bone re...

    Authors: Tao Tian, Han-yao Huang, Wei Wang, Bing Shi, Qian Zheng and Cheng-hao Li
    Citation: BioMedical Engineering OnLine 2022 21:31
  32. Integrin, beta-like 1 (ITGBL1) is involved in a variety of human malignancies. However, the information on the involvement of ITGBL1 in gastric carcinoma (GC) is limited. Hence, this study aimed further to exp...

    Authors: Zhe Wang, Liu Fu, Junjie Zhang, Yanli Ge, Cheng Guo, Rui Wang, Min Deng, Qizhi Wang and Zhirong Wang
    Citation: BioMedical Engineering OnLine 2022 21:30
  33. Falls among older adults have become a global concern. While previous studies have established associations between autonomic function indicator; heart rate variability (HRV) and blood pressure variability (BP...

    Authors: Nur Husna Shahimi, Choon-Hian Goh, Sumaiyah Mat, Renly Lim, Vivian Ci Ai Koh, Samuel R. Nyman, Maw Pin Tan and Einly Lim
    Citation: BioMedical Engineering OnLine 2022 21:29
  34. Current ankle prostheses for people with unilateral transtibial amputation (TTA) or transfemoral amputation (TFA) are unable to mimic able-bodied performance during daily activities. A new mechanical ankle–foo...

    Authors: Elke Lathouwers, Toon Ampe, María Alejandra Díaz, Romain Meeusen and Kevin De Pauw
    Citation: BioMedical Engineering OnLine 2022 21:28
  35. Increasing attention has been paid to the potential relationship between gut and lung. The bacterial dysbiosis in respiratory tract and intestinal tract is related to inflammatory response and the progress of ...

    Authors: Zhendong Wang, Chen Bai, Tingyao Hu, Changyong Luo, He Yu, Xueyan Ma, Tiegang Liu and Xiaohong Gu
    Citation: BioMedical Engineering OnLine 2022 21:27
  36. Reflexive responses to head–neck perturbations affect the injury risk in many different situations ranging from sports-related impact to car accident scenarios. Although several experiments have been conducted...

    Authors: Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko and Syn Schmitt
    Citation: BioMedical Engineering OnLine 2022 21:25
  37. This study explored the feasibility of radiofrequency (RF)-based radiomics analysis techniques for the preoperative prediction of programmed cell death protein 1 (PD-1) in patients with hepatocellular carcinom...

    Authors: Qingmin Wang, Yi Dong, Tianlei Xiao, Shiquan Zhang, Jinhua Yu, Leyin Li, Qi Zhang, Yuanyuan Wang, Yang Xiao and Wenping Wang
    Citation: BioMedical Engineering OnLine 2022 21:24
  38. Due to the steadily increasing life expectancy of the population, the need for medical aids to maintain the previous quality of life is growing. The basis for independent mobility is a functional locomotor sys...

    Authors: Lena Risse, Steven Woodcock, Jan-Peter Brüggemann, Gunter Kullmer and Hans Albert Richard
    Citation: BioMedical Engineering OnLine 2022 21:23
  39. Shock advice algorithm plays a vital role in the detection of sudden cardiac arrests on electrocardiogram signals and hence, brings about survival improvement by delivering prompt defibrillation. The last deca...

    Authors: Minh Tuan Nguyen, Thu-Hang T. Nguyen and Hai-Chau Le
    Citation: BioMedical Engineering OnLine 2022 21:22
  40. Using embedded sensors, instrumented walkways provide clinicians with important information regarding gait disturbances. However, because raw data are summarized into standard gait variables, there may be some...

    Authors: Wenting Hu, Owen Combden, Xianta Jiang, Syamala Buragadda, Caitlin J. Newell, Maria C. Williams, Amber L. Critch and Michelle Ploughman
    Citation: BioMedical Engineering OnLine 2022 21:21
  41. Early diagnosis and continuous monitoring are the key to emergency treatment and intensive care of patients with acute ischemic stroke (AIS). Nevertheless, there has not been a fully accepted method targeting ...

    Authors: Gen Li, Shengtong Yin, Man Jian, Jingbo Chen, Lingxi Zeng, Zelin Bai, Wei Zhuang, Bingxin Xu, Shengjie He, Jian Sun and Yujie Chen
    Citation: BioMedical Engineering OnLine 2022 21:20
  42. Mental illness represents a major global burden of disease worldwide. It has been hypothesised that individuals with mental illness have greater blood pressure fluctuations that lead to increased cardiovascula...

    Authors: Nur Husna Shahimi, Renly Lim, Sumaiyah Mat, Choon-Hian Goh, Maw Pin Tan and Einly Lim
    Citation: BioMedical Engineering OnLine 2022 21:19
  43. This study aims to analyze the effects of a novel dual-bearing shoulder prosthesis and a conventional reverse shoulder prosthesis on the deltoid and rotator cuff muscle forces for four different arm motions. T...

    Authors: Bernhard Weisse, Susan Lama, Gabor Piskoty, Christian Affolter and Ameet K. Aiyangar
    Citation: BioMedical Engineering OnLine 2022 21:17
  44. Patient-specific lung mechanics during mechanical ventilation (MV) can be identified from measured waveforms of fully ventilated, sedated patients. However, asynchrony due to spontaneous breathing (SB) effort ...

    Authors: Cong Zhou, J. Geoffrey Chase, Qianhui Sun, Jennifer Knopp, Merryn H. Tawhai, Thomas Desaive, Knut Möller, Geoffrey M. Shaw, Yeong Shiong Chiew and Balazs Benyo
    Citation: BioMedical Engineering OnLine 2022 21:16
  45. Age-related changes in muscle properties affect daily functioning, therefore a reliable assessment of such properties is required. We examined the effects of age on reliability, muscle quality and interrelatio...

    Authors: Iris Hagoort, Tibor Hortobágyi, Nicolas Vuillerme, Claudine J. C. Lamoth and Alessio Murgia
    Citation: BioMedical Engineering OnLine 2022 21:15
  46. The role of high-frequency oscillatory ventilation (HFOV) has long been debated. Numerous studies documented its benefits, whereas several more recent studies did not prove superiority of HFOV over protective ...

    Authors: Karel Roubík, Jakub Ráfl, Martin Rožánek, Petr Kudrna and Mikuláš Mlček
    Citation: BioMedical Engineering OnLine 2022 21:14