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  1. An intracranial aneurysm is a cerebrovascular disorder that can result in various diseases. Clinically, diagnosis of an intracranial aneurysm utilizes digital subtraction angiography (DSA) modality as gold sta...

    Authors: Haihan Duan, Yunzhi Huang, Lunxin Liu, Huming Dai, Liangyin Chen and Liangxue Zhou

    Citation: BioMedical Engineering OnLine 2019 18:110

    Content type: Research

    Published on:

  2. Currently, the mainstay of treatment in patients diagnosed with major depressive disorder (MDD) requiring medical attention is second generation anti-depressants. However, about 40% of patients treated with se...

    Authors: Naaz Kapadia, Vera Zivanovic, Bastien Moineau, Jonathan Downar, Jose Zariffa and Milos R. Popovic

    Citation: BioMedical Engineering OnLine 2019 18:109

    Content type: Research

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  4. The interplay between sleep structure and seizure probability has previously been studied using electroencephalography (EEG). Combining sleep assessment and detection of epileptic activity in ultralong-term EE...

    Authors: Sirin W. Gangstad, Kaare B. Mikkelsen, Preben Kidmose, Yousef R. Tabar, Sigge Weisdorf, Maja H. Lauritzen, Martin C. Hemmsen, Lars K. Hansen, Troels W. Kjaer and Jonas Duun-Henriksen

    Citation: BioMedical Engineering OnLine 2019 18:106

    Content type: Research

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  5. Pulmonary lobectomy has been a well-established curative treatment method for localized lung cancer. After left upper pulmonary lobectomy, the upward displacement of remaining lower lobe causes the distortion ...

    Authors: Qingtao Gu, Shouliang Qi, Yong Yue, Jing Shen, Baihua Zhang, Wei Sun, Wei Qian, Mohammad Saidul Islam, Suvash C. Saha and Jianlin Wu

    Citation: BioMedical Engineering OnLine 2019 18:105

    Content type: Research

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  6. The activation of stretch-activated channels (SACs) in cardiac myocytes, which changes the phases of action potential repolarization, is proven to be highly efficient for the conversion of atrial fibrillation....

    Authors: Heqing Zhan, Jingtao Zhang, Anquan Jiao and Qin Wang

    Citation: BioMedical Engineering OnLine 2019 18:104

    Content type: Research

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  8. The challenges of glycaemic control in critically ill patients have been debated for 20 years. While glycaemic control shows benefits inter- and intra-patient metabolic variability results in increased hypogly...

    Authors: Vincent Uyttendaele, Jennifer L. Knopp, Shaun Davidson, Thomas Desaive, Balazs Benyo, Geoffrey M. Shaw and J. Geoffrey Chase

    Citation: BioMedical Engineering OnLine 2019 18:102

    Content type: Research

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  9. Intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) are standard physical technologies of stereotactic body radiotherapy (SBRT) that are used for patients with non-small-cell lu...

    Authors: Xue Bai, Guoping Shan, Ming Chen and Binbing Wang

    Citation: BioMedical Engineering OnLine 2019 18:101

    Content type: Research

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  10. It is crucial to frequently inspect the proper operation of non-invasive electronic blood pressure monitors in various sites to prevent accidents from inaccurate blood pressure measurements, especially for lar...

    Authors: Young Jun Hwang, Gun Ho Kim, Sung Uk Yun and Kyoung Won Nam

    Citation: BioMedical Engineering OnLine 2019 18:100

    Content type: Research

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  11. Venous thromboembolism (VTE) is a major sequela after total knee arthroplasty (TKA). We prospectively compared the differences in the perioperative plasma d-dimer and fibrinogen levels between the individuals und...

    Authors: Ka-Kit Siu, Kwan-Ting Wu, Jih-Yang Ko, Feng-Sheng Wang, Wen-Yi Chou, Ching-Jen Wang and Shu-Jui Kuo

    Citation: BioMedical Engineering OnLine 2019 18:99

    Content type: Research

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  12. Conventional risk prediction techniques may not be the most suitable approach for personalized prediction for individual patients. Therefore, individualized predictive modeling based on similar patients has em...

    Authors: Ni Wang, Yanqun Huang, Honglei Liu, Xiaolu Fei, Lan Wei, Xiangkun Zhao and Hui Chen

    Citation: BioMedical Engineering OnLine 2019 18:98

    Content type: Research

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  13. Silk fibroin hydrogel, derived from Bombyx mori cocoons, has been shown to have potential effects on wound healing due to its excellent biocompatibility and less immunogenic and biodegradable properties. Many stu...

    Authors: Sirong He, Dan Shi, Zhigang Han, Zhaoming Dong, Yajun Xie, Fengmei Zhang, WenXin Zeng and Qiying Yi

    Citation: BioMedical Engineering OnLine 2019 18:97

    Content type: Research

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  14. Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation par...

    Authors: Priscila C. Antoneli, Jair T. Goulart, Isabella Bonilha, Daniela D. de Carvalho and Pedro X. de Oliveira

    Citation: BioMedical Engineering OnLine 2019 18:96

    Content type: Research

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  15. Improving imaging quality is a fundamental problem in ultrasound contrast agent imaging (UCAI) research. Plane wave imaging (PWI) has been deemed as a potential method for UCAI due to its’ high frame rate and ...

    Authors: Meng Dai, Shuying Li, Yuanyuan Wang, Qi Zhang and Jinhua Yu

    Citation: BioMedical Engineering OnLine 2019 18:95

    Content type: Research

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  16. Quantum noise intrinsically limits the quality of fluoroscopic images. The lower is the X-ray dose the higher is the noise. Fluoroscopy video processing can enhance image quality and allows further patient’s d...

    Authors: A. Sarno, E. Andreozzi, D. De Caro, G. Di Meo, A. G. M. Strollo, M. Cesarelli and P. Bifulco

    Citation: BioMedical Engineering OnLine 2019 18:94

    Content type: Research

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  17. As the only arterial structure of which two main arteries merged into one, the vertebro-basilar (VA-BA) system is one of the favorite sites of cerebral atherosclerotic plaques. The aim of this study was to inv...

    Authors: Guangyu Zhu, Yuan Wei, Qi Yuan, Jian Yang and Joon Hock Yeo

    Citation: BioMedical Engineering OnLine 2019 18:93

    Content type: Research

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  18. Sleep problem or disturbance often exists in pain or neurological/psychiatric diseases. However, sleep scoring is a time-consuming tedious labor. Very few studies discuss the 5-stage (wake/NREM1/NREM2/transiti...

    Authors: Ting-Ying Wei, Chung-Ping Young, Yu-Ting Liu, Jia-Hao Xu, Sheng-Fu Liang, Fu-Zen Shaw and Chin-En Kuo

    Citation: BioMedical Engineering OnLine 2019 18:92

    Content type: Research

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  19. Enhanced external counterpulsation (EECP) is an effective method for treating patients with cerebral ischemic stroke, while hemodynamics is the major contributing factor in the treatment of EECP. Different cou...

    Authors: Bao Li, Wenxin Wang, Boyan Mao, Yahui Zhang, Sihan Chen, Haisheng Yang, Haijun Niu, Jianhang Du, Xiaoling Li and Youjun Liu

    Citation: BioMedical Engineering OnLine 2019 18:91

    Content type: Research

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  20. Stroke-related sensory and motor deficits often steal away the independent mobility and balance from stroke survivors. Often, this compels the stroke survivors to rely heavily on their non-paretic leg during w...

    Authors: Deepesh Kumar, Nirvik Sinha, Anirban Dutta and Uttama Lahiri

    Citation: BioMedical Engineering OnLine 2019 18:90

    Content type: Research

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  21. Treadmill exercise is commonly used as an alternative to over-ground walking or running. Increasing evidence indicated the kinetics of treadmill exercise is different from that of over-ground. Biomechanics of ...

    Authors: Jie Yao, Ning Guo, Yanqiu Xiao, Zhili Li, Yinghui Li, Fang Pu and Yubo Fan

    Citation: BioMedical Engineering OnLine 2019 18:89

    Content type: Research

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  23. Carotid artery geometry is important for recapitulating a pathophysiological microenvironment to study wall shear stress (WSS)-induced endothelial dysfunction in atherosclerosis. Endothelial cells (ECs) cultur...

    Authors: Ruomeng Chen, Bo Wang, Yaxiong Liu, Jiankang He, Rong Lin and Dichen Li

    Citation: BioMedical Engineering OnLine 2019 18:87

    Content type: Research

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  24. Microelectrode arrays play an important role in prosthetic implants for neural signal recording or applying electrical pulses stimulation to target nerve system. Safety and long-term reliability are essential ...

    Authors: Hongyan Cui, Xiaobo Xie, Shengpu Xu, Leanne L. H. Chan and Yong Hu

    Citation: BioMedical Engineering OnLine 2019 18:86

    Content type: Research

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  25. Ratcheting strain is produced due to the repeated accumulation of compressive strain in cartilage and may be a precursor to osteoarthritis. The aim of this study was to investigate the ratcheting behaviors of ...

    Authors: Li-Lan Gao, Xiang-Long Lin, Dong-Dong Liu, Ling Chen, Chun-Qiu Zhang and Hong Gao

    Citation: BioMedical Engineering OnLine 2019 18:85

    Content type: Research

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  26. Electrical impedance tomography (EIT) is a noninvasive, radiation-free, and low-cost imaging modality for monitoring the conductivity distribution inside a patient. Nowadays, time-difference EIT (tdEIT) is use...

    Authors: Lu Cao, Haoting Li, Canhua Xu, Meng Dai, Zhenyu Ji, Xuetao Shi, Xiuzhen Dong, Feng Fu and Bin Yang

    Citation: BioMedical Engineering OnLine 2019 18:84

    Content type: Research

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  27. Electrical impedance tomography (EIT) has been used for functional lung imaging of regional air distributions during mechanical ventilation in intensive care units (ICU). From numerous clinical and animal stud...

    Authors: Geuk Young Jang, Ghazal Ayoub, Young Eun Kim, Tong In Oh, Chi Ryang Chung, Gee Young Suh and Eung Je Woo

    Citation: BioMedical Engineering OnLine 2019 18:83

    Content type: Research

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  28. The use of flow-diverters for non-saccular cerebral posterior circulation aneurysms requires complex deployment techniques and is associated with high mortality and morbidity. Therefore, further studies are re...

    Authors: Sergey Sindeev, Jan Stephan Kirschke, Sascha Prothmann, Sergey Frolov, Dieter Liepsch, Philipp Berg, Claus Zimmer and Benjamin Friedrich

    Citation: BioMedical Engineering OnLine 2019 18:82

    Content type: Research

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  29. The future of biomedical engineering is exciting, and prospects for biomedical engineering journals are rapidly growing. In this editorial, a brief history of Biomedical Engineering Online is outlined, along with...

    Authors: Ervin Sejdić and Fong-Chin Su

    Citation: BioMedical Engineering OnLine 2019 18:81

    Content type: Editorial

    Published on:

  30. It was highlighted that the original article [1] had an omission in the Abstract. This Correction article shows the omitted sentence: “This article [1] was awarded the SIAMOC Best Methodological Paper 2018”.

    Authors: Ilaria Arcolin, Stefano Corna, Marica Giardini, Andrea Giordano, Antonio Nardone and Marco Godi

    Citation: BioMedical Engineering OnLine 2019 18:80

    Content type: Correction

    Published on:

    The original article was published in BioMedical Engineering OnLine 2019 18:70

  31. Deep brain stimulation (DBS) has a good prospect for treating many brain diseases. Recent studies have shown that axonal activation induced by pulse stimulations may play an important role in DBS therapies thr...

    Authors: Chen Qiu, Zhouyan Feng, Lvpiao Zheng and Weijian Ma

    Citation: BioMedical Engineering OnLine 2019 18:79

    Content type: Research

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  32. Hemodialysis mainly relies on the “artificial kidney,” which plays a very important role in temporarily or permanently substituting for the kidney to carry out the exchange of waste and discharge of water. Nev...

    Authors: An-Jin Shie, Kuei-Hsing Lo, Wen-Tsann Lin, Chi-Wen Juan and Yung-Tsan Jou

    Citation: BioMedical Engineering OnLine 2019 18:78

    Content type: Research

    Published on:

  33. Temperature monitoring during high-intensity focused ultrasound (HIFU) therapy on tissue is essential to regulate the degree of thermal coagulation and to achieve the desired treatment outcomes eventually. The...

    Authors: Suhyun Park, Ngot Thi Pham, Huu-Toan Huynh and Hyun Wook Kang

    Citation: BioMedical Engineering OnLine 2019 18:77

    Content type: Research

    Published on:

  34. Several countries encourage the practice of football for rehabilitation and social inclusion purposes. For visually impaired people, football is purely sound-based, where the ball and the players are constantl...

    Authors: Francisco Yandun, Fernando A. Auat Cheein, Daniela Lorca, Omar Acevedo and Cecilia Auat Cheein

    Citation: BioMedical Engineering OnLine 2019 18:76

    Content type: Research

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  35. Irreversible electroporation (IRE) using direct current (DC) is an effective method for the ablation of cardiac tissue. A major drawback of the use of DC-IRE, however, are two problems: requirement of general ...

    Authors: René van Es, Maurits K. Konings, Bastiaan C. Du Pré, Kars Neven, Harry van Wessel, Vincent J. H. M. van Driel, Albert H. Westra, Pieter A. F. Doevendans and Fred H. M. Wittkampf

    Citation: BioMedical Engineering OnLine 2019 18:75

    Content type: Research

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  36. Human brain models and pharmacological models of brain diseases are in high demand for drug screening because animal models have been found to be less than ideal for fully representing the human brain and are ...

    Authors: Ao Fang, Dichen Li, Zhiyan Hao, Ling Wang, Binglei Pan, Lin Gao, Xiaoli Qu and Jiankang He

    Citation: BioMedical Engineering OnLine 2019 18:74

    Content type: Research

    Published on:

    The Correction to this article has been published in BioMedical Engineering OnLine 2019 18:88

  39. Patients with end-stage heart failure must receive treatment to recover cardiac function, and the current primary therapy, heart transplantation, is plagued by the limited supply of donor hearts. Bioengineered...

    Authors: Cailing Tong, Cheng Li, Baiyi Xie, Minghui Li, Xianguo Li, Zhongquan Qi and Junjie Xia

    Citation: BioMedical Engineering OnLine 2019 18:71

    Content type: Research

    Published on:

  40. Gait impairment is a risk factor for falls in patients with Parkinson’s disease (PD). Gait can be conveniently assessed by electronic walkways, but there is need to select which spatiotemporal gait variables a...

    Authors: Ilaria Arcolin, Stefano Corna, Marica Giardini, Andrea Giordano, Antonio Nardone and Marco Godi

    Citation: BioMedical Engineering OnLine 2019 18:70

    Content type: Research

    Published on:

    The Correction to this article has been published in BioMedical Engineering OnLine 2019 18:80

  42. The accuracy of the surgical amount of extraocular muscle (EOM) is key to the success of strabismus surgery. To establish an accurate eye movement model, it is of great theoretical value and clinical significa...

    Authors: Hongmei Guo, Zhipeng Gao, Baoyan Han, Lijun Zhang, Zhaoqiang Tang, Jing Chen, Lili Wang and Weiyi Chen

    Citation: BioMedical Engineering OnLine 2019 18:68

    Content type: Research

    Published on:

  43. Diabetic retinopathy (DR) is the leading cause of blindness worldwide, and therefore its early detection is important in order to reduce disease-related eye injuries. DR is diagnosed by inspecting fundus image...

    Authors: Noushin Eftekhari, Hamid-Reza Pourreza, Mojtaba Masoudi, Kamaledin Ghiasi-Shirazi and Ehsan Saeedi

    Citation: BioMedical Engineering OnLine 2019 18:67

    Content type: Research

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  45. This study was designed to investigate heat accumulation and bone thermal necrosis for various distances between holes and time delays between drillings.

    Authors: Seifollah Gholampour and Hossein Haghighi Hassanali Deh

    Citation: BioMedical Engineering OnLine 2019 18:65

    Content type: Research

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  46. Patellar tendon rupture is a potentially devastating injury. Surgical repair is the primary treatment recommended for the patients with patellar tendon ruptures. Given the tendon properties, the suture techniq...

    Authors: Chen-Yo Yen, Yi-Jung Tsai, Chih-Kun Hsiao, Feng-Chen Kao and Yuan-Kun Tu

    Citation: BioMedical Engineering OnLine 2019 18:64

    Content type: Research

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  47. Segment fusion using interbody cages supplemented with pedicle screw fixation is the most common surgery for the treatment of low back pain. However, there is still much controversy regarding the use of cages ...

    Authors: Andrea Calvo-Echenique, José Cegoñino and Amaya Perez del Palomar

    Citation: BioMedical Engineering OnLine 2019 18:63

    Content type: Research

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  48. Medical datasets, especially medical images, are often imbalanced due to the different incidences of various diseases. To address this problem, many methods have been proposed to synthesize medical images usin...

    Authors: Zekuan Yu, Qing Xiang, Jiahao Meng, Caixia Kou, Qiushi Ren and Yanye Lu

    Citation: BioMedical Engineering OnLine 2019 18:62

    Content type: Research

    Published on:

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BioMedical Engineering OnLine

ISSN: 1475-925X

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