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  1. Arterial spin labeling (ASL) provides a noninvasive way to measure cerebral blood flow (CBF). The CBF estimation from ASL is heavily contaminated by noise and the partial volume (PV) effect. The multiple measu...

    Authors: Yang Liu, Ze Wang, Ruihua Liang, Zhengrong Liang and Hongbing Lu

    Citation: BioMedical Engineering OnLine 2019 18:12

    Content type: Research

    Published on:

  2. Docetaxel (DTX) is an anticancer drug that is currently formulated with polysorbate 80 and ethanol (50:50, v/v) in clinical use. Unfortunately, this formulation causes hypersensitivity reactions, leading to se...

    Authors: Na Qu, Yating Sun, Yujing Li, Fei Hao, Pengyu Qiu, Lesheng Teng, Jing Xie and Yin Gao

    Citation: BioMedical Engineering OnLine 2019 18:11

    Content type: Research

    Published on:

  4. Acute myocardial infarction (AMI) is the common cause of mortality in developed countries. The feasibility of whole-genome gene expression analysis to identify outcome-related genes and dysregulated pathways r...

    Authors: Zhihua Liu, Chenguang Ma, Junhua Gu and Ming Yu

    Citation: BioMedical Engineering OnLine 2019 18:9

    Content type: Research

    Published on:

  5. Quantizing the Breast Imaging Reporting and Data System (BI-RADS) criteria into different categories with the single ultrasound modality has always been a challenge. To achieve this, we proposed a two-stage gr...

    Authors: Yunzhi Huang, Luyi Han, Haoran Dou, Honghao Luo, Zhen Yuan, Qi Liu, Jiang Zhang and Guangfu Yin

    Citation: BioMedical Engineering OnLine 2019 18:8

    Content type: Research

    Published on:

  6. Ultrasound computed tomography (USCT) is usually realized with a ring array. It can provide better imaging performance and more tissue information by emitting and receiving the ultrasound signal in different d...

    Authors: Xinming Jiang, Yang Xiao, Yuanyuan Wang, Jinhua Yu and Hairong Zheng

    Citation: BioMedical Engineering OnLine 2019 18:7

    Content type: Research

    Published on:

  10. A direct blow to the knee is one way to injure the anterior cruciate ligament (ACL), e.g., during a football or traffic accident. Robot-assisted therapy (RAT) rehabilitation, simulating regular walking, improv...

    Authors: Juan C. Yepes, Mario A. Portela, Álvaro J. Saldarriaga, Vera Z. Pérez and Manuel J. Betancur

    Citation: BioMedical Engineering OnLine 2019 18:3

    Content type: Research

    Published on:

  11. Lung segmentation constitutes a critical procedure for any clinical-decision supporting system aimed to improve the early diagnosis and treatment of lung diseases. Abnormal lungs mainly include lung parenchyma...

    Authors: Mingjie Xu, Shouliang Qi, Yong Yue, Yueyang Teng, Lisheng Xu, Yudong Yao and Wei Qian

    Citation: BioMedical Engineering OnLine 2019 18:2

    Content type: Research

    Published on:

  12. There exists a growing need for a cost-effective, reliable, and portable pulsation simulator that can generate a wide variety of pulses depending on age and cardiovascular disease. For constructing compact pul...

    Authors: Tae-Heon Yang, Gwanghyun Jo, Jeong-Hoi Koo, Sam-Yong Woo, Jaeuk U. Kim and Young-Min Kim

    Citation: BioMedical Engineering OnLine 2019 18:1

    Content type: Research

    Published on:

  13. Optical imaging is one of the most common, low-cost imaging tools used for investigating the tumor biological behavior in vivo. This study explores the feasibility and sensitivity of a near infrared fluorescen...

    Authors: Kedi Zhou, Yichen Ding, Ivan Vuletic, Yonglu Tian, Jun Li, Jinghao Liu, Yixing Huang, Hongfang Sun, Changhui Li, Qiushi Ren and Yanye Lu

    Citation: BioMedical Engineering OnLine 2018 17:187

    Content type: Research

    Published on:

  14. Electrical impedance tomography (EIT) is an emerging imaging technology that has been used to monitor brain injury and detect acute stroke. The time and frequency properties of electrode–skin contact impedance...

    Authors: Lin Yang, Heng Li, Junjie Ding, Weichen Li, Xiuzhen Dong, Zhihong Wen and Xuetao Shi

    Citation: BioMedical Engineering OnLine 2018 17:186

    Content type: Research

    Published on:

  15. Detection and quantification of cyclic alternating patterns (CAP) components has the potential to serve as a disease bio-marker. Few methods exist to discriminate all the different CAP components, they do not ...

    Authors: Fátima Machado, Francisco Sales, Clara Santos, António Dourado and C. A. Teixeira

    Citation: BioMedical Engineering OnLine 2018 17:185

    Content type: Research

    Published on:

  16. Phase-rectified signal averaging (PRSA) was often applied to assess the cardiac vagal modulation. Despite its broad use, this method suffers from the confounding effects of anomalous variants of sinus rhythm. ...

    Authors: Hongyun Liu, Ping Zhan, Jinlong Shi, Guojing Wang, Buqing Wang and Weidong Wang

    Citation: BioMedical Engineering OnLine 2018 17:184

    Content type: Research

    Published on:

  17. Mobile health apps (mHealth apps) are increasing in popularity and utility for the management of many chronic diseases. Although the current reimbursement structure for mHealth apps is lagging behind the rapid...

    Authors: Alice Lan, Alexandra Lee, Kristin Munroe, Cameron McRae, Linda Kaleis, Karim Keshavjee and Aziz Guergachi

    Citation: BioMedical Engineering OnLine 2018 17:183

    Content type: Research

    Published on:

  18. Myocardial deformation measured by strain is used to detect electro-mechanical abnormalities in cardiac tissue. Estimation of myocardial properties from regional strain patterns when multiple pathologies are p...

    Authors: Borut Kirn, John Walmsley and Joost Lumens

    Citation: BioMedical Engineering OnLine 2018 17:182

    Content type: Research

    Published on:

  20. The study presents a recursive least-squares estimation method with an exponential forgetting factor for noise removal in functional near-infrared spectroscopy data and extraction of hemodynamic responses (HRs...

    Authors: Hoang-Dung Nguyen, So-Hyeon Yoo, M. Raheel Bhutta and Keum-Shik Hong

    Citation: BioMedical Engineering OnLine 2018 17:180

    Content type: Research

    Published on:

  23. Sit-to-stand movements are a necessary part of daily life, and excessive mechanical stress on the articular cartilage has been reported to encourage the progression of osteoarthritis. Although a change in hip ...

    Authors: Takuma Inai, Tomoya Takabayashi, Mutsuaki Edama and Masayoshi Kubo

    Citation: BioMedical Engineering OnLine 2018 17:177

    Content type: Research

    Published on:

  24. This paper presents a novel method for early detection of hematomas using highly sensitive optical fNIR imaging methods based on broadband photon migration. The NIR experimental measurements of inhomogeneous m...

    Authors: E. Sultan, A. H. Gandjbakhche, K. Pourrezaei and A. S. Daryoush

    Citation: BioMedical Engineering OnLine 2018 17:176

    Content type: Research

    Published on:

  26. A number of various techniques were proposed to stabilized ankle arthrodesis, among them external and internal fixation. Appropriate balance and adequate distribution of lower limb loads determine normal biome...

    Authors: Piotr Morasiewicz, Grzegorz Konieczny, Maciej Dejnek, Leszek Morasiewicz, Wiktor Urbański, Mirosław Kulej, Szymon Łukasz Dragan, Szymon Feliks Dragan and Łukasz Pawik

    Citation: BioMedical Engineering OnLine 2018 17:174

    Content type: Research

    Published on:

  27. Preparation of a uniform angle of walls is essential for making an ideal convergence angle in fixed prosthodontics. We developed a de novo detachable angle-correction apparatus for dental handpiece drills that...

    Authors: Yoon Nam, Mi Young Eo and Soung Min Kim

    Citation: BioMedical Engineering OnLine 2018 17:173

    Content type: Research

    Published on:

  28. The periodontal ligament (PDL) plays a key role in alveolar bone remodeling and resorption during tooth movements. The prediction of tooth mobility under functional dental loads requires a deep understanding o...

    Authors: Bin Wu, Yipeng Fu, Haotian Shi, Bin Yan, Ruxin Lu, Songyun Ma and Bernd Markert

    Citation: BioMedical Engineering OnLine 2018 17:172

    Content type: Research

    Published on:

  29. This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical di...

    Authors: Shaun Davidson, Chris Pretty, Joel Balmer, Thomas Desaive and J. Geoffrey Chase

    Citation: BioMedical Engineering OnLine 2018 17:171

    Content type: Research

    Published on:

  31. Extracting fundamental information from data, thus underlining hidden structures or removing noisy information, is one of the most important aims in different scientific fields especially in biological and med...

    Authors: Nicola Amoroso, Domenico Diacono, Marianna La Rocca, Roberto Bellotti and Sabina Tangaro

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):162

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  32. In case of significant imperfections on the cornea, data acquisition is difficult and a significant level of missing data could require the interpolation of important areas of the cornea, resulting in a very a...

    Authors: Francisco Cavas-Martínez, Daniel G. Fernández-Pacheco, Dolores Parras, Francisco J. F. Cañavate, Laurent Bataille and Jorge Alió

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):161

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  33. Like other scientific fields, such as cosmology, high-energy physics, or even the life sciences, medicine and healthcare face the challenge of an extremely quick transformation into data-driven sciences. This ...

    Authors: Alfredo Vellido, Vicent Ribas, Carles Morales, Adolfo Ruiz Sanmartín and Juan Carlos Ruiz Rodríguez

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):135

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  34. Laboratory rats play a critical role in research because they provide a biological model that can be used for evaluating the affectation of diseases and injuries, and for the evaluation of the effectiveness of...

    Authors: S. Ivvan Valdez, Josué González-Sandoval, Sergio Dueñas-Jiménez, Nancy Elizabeth Franco Rodríguez, Sulema Torres-Ramos and Gerardo Mendizabal-Ruiz

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):134

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  35. Pseudomonas aeruginosa is a common bacterium which is recognized for its association with hospital-acquired infections and its advanced antibiotic resistance mechanisms. Tuberculosis, one of the major causes of m...

    Authors: Dan Wang, Jingyu Li and Lusheng Wang

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):133

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  36. The human activity monitoring technology is one of the most important technologies for ambient assisted living, surveillance-based security, sport and fitness activities, healthcare of elderly people. The acti...

    Authors: Giorgio Biagetti, Paolo Crippa, Laura Falaschetti, Simone Orcioni and Claudio Turchetti

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):132

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  37. This paper studies the temporal consistency of health care expenditures in a large state Medicaid program. Predictive machine learning models were used to forecast the expenditures, especially for the high-cos...

    Authors: Chengliang Yang, Chris Delcher, Elizabeth Shenkman and Sanjay Ranka

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 1):131

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  38. Mechanical ventilation is an essential therapy to support critically ill respiratory failure patients. Current standards of care consist of generalised approaches, such as the use of positive end expiratory pr...

    Authors: Vincent J. Major, Yeong Shiong Chiew, Geoffrey M. Shaw and J. Geoffrey Chase

    Citation: BioMedical Engineering OnLine 2018 17:169

    Content type: Review

    Published on:

  39. The main objective of this paper is to develop and test the ability of the Leap Motion controller (LMC) to assess the motor dysfunction in patients with Parkinson disease (PwPD) based on the MDS-UPDRSIII exerc...

    Authors: A. H. Butt, E. Rovini, C. Dolciotti, G. De Petris, P. Bongioanni, M. C. Carboncini and F. Cavallo

    Citation: BioMedical Engineering OnLine 2018 17:168

    Content type: Research

    Published on:

  40. After publication, it was highlighted that the original publication [1] contained a spelling mistake in the first name of Marcelo Gattas. This was incorrectly captured as Marelo Gattass in the original article...

    Authors: Alex M. Santos, Anselmo C. Paiva, Adriana P. M. Santos, Steve A. T. Mpinda, Daniel L. Gomes Jr., Aristófanes C. Silva, Geraldo Braz Jr., João Dallyson S. de Almeida and Marcelo Gattas

    Citation: BioMedical Engineering OnLine 2018 17:167

    Content type: Correction

    Published on:

    The original article was published in BioMedical Engineering OnLine 2018 17:160

  41. Biomedical named entity recognition (Bio-NER) is a fundamental task in handling biomedical text terms, such as RNA, protein, cell type, cell line, and DNA. Bio-NER is one of the most elementary and core tasks ...

    Authors: Hye-Jeong Song, Byeong-Cheol Jo, Chan-Young Park, Jong-Dae Kim and Yu-Seop Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):158

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  42. Polymerase chain reaction (PCR) is used in nucleic acid tests of infectious diseases in point-of-care testing. Previous studies have demonstrated real-time PCR that uses a micro-PCR chip made of packing tape, ...

    Authors: Ji-Soo Hwang, Jong-Dae Kim, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):156

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  43. The significant advancement in the mobile sensing technologies has brought great interests on application development for the Internet-of-Things (IoT). With the advantages of contactlessness data retrieval and...

    Authors: Cheng-Fa Chiang, Fang-Ming Hsu and Kuo-Hui Yeh

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):154

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  44. In this paper, we propose a system for data monitoring and control of polymerase chain reaction (PCR) externally. PCR is a technique for amplifying a desired DNA molecule by repeatedly synthesizing a specific ...

    Authors: Jong-Dae Kim, So-Yeon Lee, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):153

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  45. Screening test using CA-125 is the most common test for detecting ovarian cancer. However, the level of CA-125 is diverse by variable condition other than ovarian cancer. It has led to misdiagnosis of ovarian ...

    Authors: Hye-Jeong Song, Eun-Suk Yang, Jong-Dae Kim, Chan-Young Park, Min-Sun Kyung and Yu-Seop Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):152

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  46. In general, the image analysis of nucleic acid for detecting DNA is dependent on the gel documentation system. These experiments may deal with harmful staining agents and are time consuming. To address these i...

    Authors: Deuk-Ju Lee, Jong-Dae Kim, Yu-Seop Kim, Hye-Jeong Song and Chan-Young Park

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):150

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  47. The purpose of this study was to investigate the efficacy of moxibustion therapy on weight loss, waist circumference and waist-to-hip ratio in young adult females. An experimental design, 51 Asian females were...

    Authors: Ching-Hsiu Hsieh, Chi-Chuan Tseng, Ju-Yu Shen and Pei-Ying Chuang

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):149

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

    The Retraction Note to this article has been published in BioMedical Engineering OnLine 2020 19:6

  48. In the past, manufacture of prosthetic socket by using traditional handmade method not only consumed research time but also required a special assembly approach. Recently, reverse engineering and rapid prototy...

    Authors: Cheung-Hwa Hsu, Chao-Hui Ou, Wei-Lun Hong and Yu-Han Gao

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):145

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  49. The accuracy and precision of liquid handling can be altered by several causes including wearing or failure of parts, and human error. The last cause is crucial since point-of-care testing (POCT) devices can b...

    Authors: Chan-Young Park, Jun Yeon, Hye-Jeong Song, Yu-Seop Kim, Ki-Bong Nahm and Jong-Dae Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):144

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

  50. Recently, automatic molecular diagnostic devices to extract DNA have been extensively developed using magnetic beads. While various methods can be applied to the control of the beads, the efficiency of the con...

    Authors: Chang-Young Park, Young-Hyun Park, Yu-Seop Kim, Hye-Jeong Song and Jong-Dae Kim

    Citation: BioMedical Engineering OnLine 2018 17(Suppl 2):143

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 2

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