Thermally significant blood flows into locally cooled diseased tissues and warm them during cryosurgery so that the iceball is often hard to cover the whole diseased volume. This paper is aimed at investigatin...
Authors: Yong-Chang Zheng, Jun-Hong Wu, Zhi-Zhu He and Shao-Jiong Huang
The multiple-breath washout (MBW) is able to provide information about the distribution of ventilation-to-volume (v/V) ratios in the lungs. However, the classical, all-parallel model may return skewed results ...
Authors: Gabriel Casulari Motta-Ribeiro, Frederico Caetano Jandre, Hermann Wrigge and Antonio Giannella-Neto
Limits for exposure to radiofrequency (RF) contact currents are specified in the two dominant RF safety standards and guidelines developed by the Institute of Electrical and Electronics Engineers (IEEE) and th...
Two international guidelines/standards for human protection from electromagnetic fields define the specific absorption rate (SAR) averaged over 10 g of tissue as a metric for protection against localized radio...
Authors: Sachiko Kodera, Jose Gomez-Tames and Akimasa Hirata
Red blood cells (RBCs) deform significantly and repeatedly when passing through narrow capillaries and delivering dioxygen throughout the body. Deformability of RBCs is a key characteristic, largely governed b...
Authors: Sarah Barns, Marie Anne Balanant, Emilie Sauret, Robert Flower, Suvash Saha and YuanTong Gu
R-wave synchronised atrial pacing is an effective temporary pacing therapy in infants with postoperative junctional ectopic tachycardia. In the technique currently used, adverse short or long intervals between...
Authors: Andreas Entenmann, Miriam Michel, Bruno Ismer and Roman Gebauer
Results of finite element (FE) analyses can give insight into musculoskeletal diseases if physiological boundary conditions, which include the muscle forces during specific activities of daily life, are consid...
Authors: Arnaud Diffo Kaze, Stefan Maas, Pierre-Jean Arnoux, Claude Wolf and Dietrich Pape
This paper presents quantitative analysis of blood flow shear stress by measuring the carotid arterial wall shear stress (WSS) and the intima-media thickness (IMT) of experimental rabbits fed with high-fat fee...
Authors: Bo Zhang, Junyi Gu, Ming Qian, Lili Niu, Hui Zhou and Dhanjoo Ghista
Adolescent idiopathic scoliosis, in which obvious curves are visible in radiographic images, is also seen in combination with lumps in the back. These lumps contribute to inclination, which can be measured by ...
Authors: Hsuan-Hsiao Ma, Ching-Lung Tai, Lih-Huei Chen, Chi-Chien Niu, Wen-Jer Chen and Po-Liang Lai
Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstru...
Authors: Hyeonha Hwang, Hee-Jae Jeon, Kin Choong Yow, Ho Sik Hwang and EuiHeon Chung
Human adipose-derived stem cells (hADSCs) are capable of differentiating into many cells such as cardiac cells. Different types of inducers are used for cardiac cell differentiation, but this question still re...
Authors: Zahra Bagheri-Hosseinabadi, Parvin Salehinejad and Seyed Alireza Mesbah-Namin
Swallowing is a continuous process with substantive interdependencies among different muscles, and it plays a significant role in our daily life. The aim of this study was to propose a novel technique based on...
Authors: Mingxing Zhu, Bin Yu, Wanzhang Yang, Yanbing Jiang, Lin Lu, Zhen Huang, Shixiong Chen and Guanglin Li
Ocular images play an essential role in ophthalmological diagnoses. Having an imbalanced dataset is an inevitable issue in automated ocular diseases diagnosis; the scarcity of positive samples always tends to ...
The purpose of this study was to design a customized fixation plate for mandibular angle fracture using topological optimization based on the biomechanical properties of the two conventional fixation systems, ...
Authors: Yun-feng Liu, Ying-ying Fan, Xian-feng Jiang and Dale A. Baur
Several methods including free-hand technique, fluoroscopic guidance, image-guided navigation, computer-assisted surgery system, robotic platform and patient’s specific templates are being used for pedicle scr...
Authors: Farhad Azimifar, Kamran Hassani, Amir Hossein Saveh and Farhad Tabatabai Ghomsheh
In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associate...
Effect of neurofeedback training (NFT) on enhancement of cognitive function or amelioration of clinical symptoms is inconclusive. The trainability of brain rhythm using a neurofeedback system is uncertainty be...
Coronary arterial stenoses, particularly serial stenoses in a single branch, are responsible for complex hemodynamic properties of the coronary arterial trees, and the uncertain prognosis of invasive intervent...
Authors: Xin Liu, Changnong Peng, Yufa Xia, Zhifan Gao, Pengcheng Xu, Xiaoqing Wang, Zhanchao Xian, Youbing Yin, Liqun Jiao, Defeng Wang, Lin Shi, Wenhua Huang, Xin Liu and Heye Zhang
For mechanically ventilated patients with acute respiratory distress syndrome (ARDS), suboptimal PEEP levels can cause ventilator induced lung injury (VILI). In particular, high PEEP and high peak inspiratory ...
Authors: Ruby Langdon, Paul D. Docherty, Christoph Schranz and J. Geoffrey Chase
Various kinds of data mining algorithms are continuously raised with the development of related disciplines. The applicable scopes and their performances of these algorithms are different. Hence, finding a sui...
Authors: Yiyan Zhang, Yi Xin, Qin Li, Jianshe Ma, Shuai Li, Xiaodan Lv and Weiqi Lv
3D ultrasound volume reconstruction from B-model ultrasound slices can provide more clearly and intuitive structure of tissue and lesion for the clinician.
Authors: Weijian Cong, Jian Yang, Danni Ai, Hong Song, Gang Chen, Xiaohui Liang, Ping Liang and Yongtian Wang
Cartilage elasticity changes with cartilage degeneration. Hence, cartilage elasticity detection might be an alternative to traditional imaging methods for the early diagnosis of osteoarthritis. Based on the wa...
Authors: Hao Xu, Shigao Chen, Kai-Nan An and Zong-Ping Luo
Non-proliferative diabetic retinopathy is the early stage of diabetic retinopathy. Automatic detection of non-proliferative diabetic retinopathy is significant for clinical diagnosis, early screening and cours...
Authors: Zhitao Xiao, Xinpeng Zhang, Lei Geng, Fang Zhang, Jun Wu, Jun Tong, Philip O. Ogunbona and Chunyan Shan
This study proposed an effective method based on the wavelet multi-scale α-entropy features of heart rate variability (HRV) for the recognition of paroxysmal atrial fibrillation (PAF). This new algorithm combines...
Swallowing impairment is a common complication in various geriatric and neurodegenerative diseases. Swallowing kinematic analysis is essential to quantitatively evaluate the swallowing motion of the oropharyng...
Authors: Woo Hyung Lee, Changmook Chun, Han Gil Seo, Seung Hak Lee and Byung-Mo Oh
Exposure to solar ultraviolet radiation is a well-known cause of skin cancer. This is problematic for outdoor workers. In Denmark alone, occupational skin cancer poses a significant health and safety risk for ...
Authors: Kasper Grandahl, Ole Steen Mortensen, David Zim Sherman, Brian Køster, Paul-Anker Lund, Kristina Sophie Ibler and Paul Eriksen
Peripheral neuropathic desensitization associated with aging, diabetes, alcoholism and HIV/AIDS, affects tens of millions of people worldwide, and there is little or no treatment available to improve sensory f...
Authors: David Karpul, Gregory K. Cohen, Gaetano D. Gargiulo, André van Schaik, Sarah McIntyre and Paul P. Breen
Nowadays, the whole world is being concerned with a major health problem, which is diabetes. A very common symptom of diabetes is the diabetic foot ulcer (DFU). The early detection of such foot complications c...
Authors: Luay Fraiwan, Mohanad AlKhodari, Jolu Ninan, Basil Mustafa, Adel Saleh and Mohammed Ghazal
Hip fracture of elderly people—suffering from osteoporosis—is a severe public health concern, which can be reduced by providing a prior assessment of hip fracture risk. Image-based finite element analysis (FEA...
Modeling physiological signals is a complex task both for understanding and synthesize biomedical signals. We propose a deep neural network model that learns and synthesizes biosignals, validated by the morpho...
Authors: David Belo, João Rodrigues, João R. Vaz, Pedro Pezarat-Correia and Hugo Gamboa
Sunglasses popularity skyrocketed since its advent. The ongoing trend led to the creation of standards to protect consumers from injuries and secondary hazards due to spectacles use. In Brazil, the correspondi...
At present, infrared (IR) imaging is used both as a non-invasive and a non-ionizing technology. Using an IR camera, it is possible to measure body surface temperature in order to detect tumors and malignant ce...
Heart rate fluctuates beat-by-beat asymmetrically which is known as heart rate asymmetry (HRA). It is challenging to assess HRA robustly based on short-term heartbeat interval series.
Authors: Chang Yan, Peng Li, Lizhen Ji, Lianke Yao, Chandan Karmakar and Changchun Liu
Sleep and sleep quality assessment by means of sleep stage analysis is important for both scientific and clinical applications. Unfortunately, the presently preferred method, polysomnography (PSG), requires co...
Authors: Kaare B. Mikkelsen, David Bové Villadsen, Marit Otto and Preben Kidmose
Heart rate variability (HRV) is a widespread non-invasive technique to assess cardiac autonomic function. Time and frequency domain analyses have been used in HRV studies, and their interpretations are linked ...
In the state of the art finite element AHBMs for car crash analysis in the LS-DYNA software material named *MAT_MUSCLE (*MAT_156) is used for active muscles modeling. It has three elements in parallel configur...
Authors: Christian Kleinbach, Oleksandr Martynenko, Janik Promies, Daniel F. B. Haeufle, Jörg Fehr and Syn Schmitt
Reclining wheelchair users often add one or more sitting assistive devices to their wheelchairs, but the effect of these additional sitting assistive devices on the risk of pressure ulcers has rarely been inve...
Ensemble Empirical Mode Decomposition (EEMD) has been popularised for single-channel Electromyography (EMG) signal processing as it can effectively extract the temporal information of the EMG time series. Howe...
Authors: Yi Zhang, Peng Xu, Peiyang Li, Keyi Duan, Yuexin Wen, Qin Yang, Tao Zhang and Dezhong Yao
Quantitative gait analysis can provide a description of joint kinematics and dynamics, and it is recognized as a clinically useful tool for functional assessment, diagnosis and intervention planning. Clinicall...
Authors: Valentina Camomilla, Andrea Cereatti, Andrea Giovanni Cutti, Silvia Fantozzi, Rita Stagni and Giuseppe Vannozzi
Nowadays, sleep quality is one of the most important measures of healthy life, especially considering the huge number of sleep-related disorders. Identifying sleep stages using polysomnographic (PSG) signals i...
Authors: Shirin Najdi, Ali Abdollahi Gharbali and José Manuel Fonseca
Examination of physiological processes and the influences of the drugs on them can be efficiently supported by mathematical modeling. One of the biggest problems is related to the exact fitting of the paramete...
Authors: Magdalena Ochab, Krzysztof Puszynski and Andrzej Swierniak
The present review collects the most relevant empirical evidence available in the literature until date regarding the effects of transcranial direct current stimulation (tDCS) on the human motor function. tDCS...
Authors: Ana Sánchez-Kuhn, Cristian Pérez-Fernández, Rosa Cánovas, Pilar Flores and Fernando Sánchez-Santed
Biology is experiencing a gradual but fast transformation from a laboratory-centred science towards a data-centred one. As such, it requires robust data engineering and the use of quantitative data analysis me...
This paper presents the preliminary results of a novel rehabilitation therapy for cervical and trunk control of children with cerebral palsy (CP) based on serious videogames and physical exercise.
Authors: Miguel A. Velasco, Rafael Raya, Luca Muzzioli, Daniela Morelli, Abraham Otero, Marco Iosa, Febo Cincotti and Eduardo Rocon
The characterization of protein–peptide interactions is a challenge for computational molecular docking. Protein–peptide docking tools face at least two major difficulties: (1) efficient sampling of large-scal...
Authors: Mateusz Kurcinski, Maciej Blaszczyk, Maciej Pawel Ciemny, Andrzej Kolinski and Sebastian Kmiecik
A key challenge in the realm of human disease research is next generation sequencing (NGS) interpretation, whereby identified filtered variant-harboring genes are associated with a patient’s disease phenotypes...
Authors: Noa Rappaport, Simon Fishilevich, Ron Nudel, Michal Twik, Frida Belinky, Inbar Plaschkes, Tsippi Iny Stein, Dana Cohen, Danit Oz-Levi, Marilyn Safran and Doron Lancet
Many protein–protein interactions are mediated by a short linear motif. Usually, amino acid sequences of those motifs are known or can be predicted. It is much harder to experimentally characterize or predict ...
Authors: Maciej Pawel Ciemny, Mateusz Kurcinski, Maciej Blaszczyk, Andrzej Kolinski and Sebastian Kmiecik
The immunotoxicity of engine exhausts is of high concern to human health due to the increasing prevalence of immune-related diseases. However, the evaluation of immunotoxicity of engine exhausts is currently b...
Gene expression analyses demand appropriate reference genes (RGs) for normalization, in order to obtain reliable assessments. Ideally, RG expression levels should remain constant in all cells, tissues or exper...
Authors: Rosario Carmona, Macarena Arroyo, María José Jiménez-Quesada, Pedro Seoane, Adoración Zafra, Rafael Larrosa, Juan de Dios Alché and M. Gonzalo Claros
Currently, cannulated pedicle screws have been widely used in minimal invasive or navigation techniques. However, the stress distribution and the strength of different core diameters of cannulated screw are no...
Authors: Chia-Ming Chang, Yu-Shu Lai and Cheng-Kung Cheng
