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  1. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, and is related to disturbed lipid metabolism and redox homeostasis. However, a definitive drug treatment has not been approv...

    Authors: Mingming Zhai, Chenxu Zhang, Jinxiu Cui, Juan Liu, Yuanzhe Li, Kangning Xie, Erping Luo and Chi Tang
    Citation: BioMedical Engineering OnLine 2023 22:51
  2. Over the decades, many publications have established respiratory muscle training (RMT) as an effective way in improving respiratory dysfunction in multiple populations. The aim of the paper is to determine the...

    Authors: Muhammad Imran Ramli, Nur Azah Hamzaid, Julia Patrick Engkasan and Juliana Usman
    Citation: BioMedical Engineering OnLine 2023 22:50
  3. Mechanical ventilation is an essential component in the treatment of patients with acute respiratory distress syndrome. Prompt adaptation of the settings of a ventilator to the variable needs of patients is es...

    Authors: Philip von Platen, Philipp A. Pickerodt, Martin Russ, Mahdi Taher, Lea Hinken, Wolfgang Braun, Rainer Köbrich, Anake Pomprapa, Roland C. E. Francis, Steffen Leonhardt and Marian Walter
    Citation: BioMedical Engineering OnLine 2023 22:47
  4. Optical Coherence Tomograph (OCT) imaging technology can be used to examine, in vivo, the human ET. At present, it is impossible to achieve the OCT scanning vivo and ex vivo in the same individual human body, ...

    Authors: Xiao-Mei Sun, Zhi-Wen Xiao, Jia-Qi Luo, Qing-Yu Gu, Hui-Qing Zhang, Bai-Ling Li, Shi-Min Zhuang and Guan-Ping Zhang
    Citation: BioMedical Engineering OnLine 2023 22:46
  5. Since myocardial work (MW) and left atrial strain are valuable for screening coronary artery disease (CAD), this study aimed to develop a novel CAD screening approach based on machine learning-enhanced echocar...

    Authors: Ying Guo, Chenxi Xia, You Zhong, Yiliang Wei, Huolan Zhu, Jianqiang Ma, Guang Li, Xuyang Meng, Chenguang Yang, Xiang Wang and Fang Wang
    Citation: BioMedical Engineering OnLine 2023 22:44
  6. Adaptive gait involves the ability to adjust the leading foot in response to the requirement of dynamic environments during walking. Accurate adjustments of the minimum toe clearance (MTC) height and step leng...

    Authors: Suzanne Martin, Simon B. Taylor, Blynn L. Shideler, Rajna Ogrin and Rezaul Begg
    Citation: BioMedical Engineering OnLine 2023 22:43
  7. Motor imagery is a cognitive process of imagining a performance of a motor task without employing the actual movement of muscles. It is often used in rehabilitation and utilized in assistive technologies to co...

    Authors: Luka Batistić, Jonatan Lerga and Isidora Stanković
    Citation: BioMedical Engineering OnLine 2023 22:41
  8. The progression of Alzheimer’s dementia (AD) can be classified into three stages: cognitive unimpairment (CU), mild cognitive impairment (MCI), and AD. The purpose of this study was to implement a machine lear...

    Authors: Sang Won Park, Na Young Yeo, Jinsu Lee, Suk-Hee Lee, Junghyun Byun, Dong Young Park, Sujin Yum, Jung-Kyeom Kim, Gihwan Byeon, Yeshin Kim and Jae-Won Jang
    Citation: BioMedical Engineering OnLine 2023 22:40
  9. Ballet is a highly technical and physically demanding dance form involving extensive end-range lumbar movements and emphasizing movement smoothness and gracefulness. A high prevalence of non-specific low back ...

    Authors: Chai-Wei Lin, Yi-Ting Fang, Jeng-Feng Yang, Bih-Jen Hsue and Cheng-Feng Lin
    Citation: BioMedical Engineering OnLine 2023 22:39
  10. To investigate the application effect of artificial intelligence (AI)-based fundus screening system in real-world clinical environment.

    Authors: Shujuan Cao, Rongpei Zhang, Aixin Jiang, Mayila Kuerban, Aizezi Wumaier, Jianhua Wu, Kaihua Xie, Mireayi Aizezi, Abudurexiti Tuersun, Xuanwei Liang and Rongxin Chen
    Citation: BioMedical Engineering OnLine 2023 22:38
  11. Although titanium plates/screws are effective fixation methods (FM) after L-shaped osteotomy reduction malarplasty (LORM), the ideal FM remains controversial. This first finite element analysis (FEA) aimed to ...

    Authors: Mohammed Qasem Al-Watary, Heyou Gao, Libin Song, Yingyou He, Yiyuan Wei and Jihua Li
    Citation: BioMedical Engineering OnLine 2023 22:37
  12. Brain-computer interfaces (BCIs) are emerging as a promising tool for upper limb recovery after stroke, and motor tasks are an essential part of BCIs for patient training and control of rehabilitative/assistiv...

    Authors: Jianghong Fu, ZeWu Jiang, Xiaokang Shu, Shugeng Chen and Jie Jia
    Citation: BioMedical Engineering OnLine 2023 22:36

    The Correction to this article has been published in BioMedical Engineering OnLine 2023 22:60

  13. Physics-based cardiovascular models are only recently being considered for disease diagnosis or prognosis in clinical settings. These models depend on parameters representing the physical and physiological pro...

    Authors: Nikolai L. Bjørdalsbakke, Jacob Sturdy, Emma M. L. Ingeström and Leif R. Hellevik
    Citation: BioMedical Engineering OnLine 2023 22:34
  14. Bone regeneration after injury or after surgical bone removal due to disease is a serious medical challenge. A variety of materials are being tested to replace a missing bone or tooth. Regeneration requires ce...

    Authors: Jana Dvorakova, Lucie Wiesnerova, Petra Chocholata, Vlastimil Kulda, Lukas Landsmann, Miroslava Cedikova, Michaela Kripnerova, Lada Eberlova and Vaclav Babuska
    Citation: BioMedical Engineering OnLine 2023 22:33
  15. Isolated ACL reconstructions (ACLR) demonstrate limitations in restoring native knee kinematics. This study investigates the knee mechanics of ACLR plus various anterolateral augmentations using a patient-spec...

    Authors: Sara Sadat Farshidfar, Joseph Cadman, Thomas Neri, David Parker, Richard Appleyard and Danè Dabirrahmani
    Citation: BioMedical Engineering OnLine 2023 22:31
  16. Major trauma is a condition that can result in severe bone damage. Customised orthopaedic reconstruction allows for limb salvage surgery and helps to restore joint alignment. For the best possible outcome thre...

    Authors: Daniel Nolte, Shuqiao Xie and Anthony M. J. Bull
    Citation: BioMedical Engineering OnLine 2023 22:30
  17. Monitoring the body temperature of premature infants is vital, as it allows optimal temperature control and may provide early warning signs for severe diseases such as sepsis. Thermography may be a non-contact...

    Authors: Florian Voss, Noah Brechmann, Simon Lyra, Jöran Rixen, Steffen Leonhardt and Christoph Hoog Antink
    Citation: BioMedical Engineering OnLine 2023 22:28
  18. Percutaneous coronary interventions (PCIs) within left main coronary arteries are high-risk procedures that require optimization of interactions between stent(s) and diseased vessels. Optical Coherence Tomogra...

    Authors: Thomas F. Valenzuela III and Paul A. Iaizzo
    Citation: BioMedical Engineering OnLine 2023 22:27
  19. Infusion Pumps (IP) are medical devices that were developed in the 1960s and generate fluid flow at pressures higher than that of normal blood pressure. Various hospital sectors make use of them, and they have...

    Authors: Mayla dos S. Silva, Joabe Lima Araújo, Gustavo A. M. de A. Nunes, Mário Fabrício F. Rosa, Glécia V. da Silva Luz, Suélia de S. R. F. Rosa and Antônio Piratelli-Filho
    Citation: BioMedical Engineering OnLine 2023 22:26
  20. Core body temperature (CBT) is a key vital sign and fever is an important indicator of disease. In the past decade, there has been growing interest for vital sign monitoring technology that may be embedded in ...

    Authors: Samuel Etienne, Ruben Oliveras, Giovanni Schiboni, Lukas Durrer, Fabien Rochat, Philipp Eib, Michele Zahner, Michael Osthoff, Stefano Bassetti and Jens Eckstein
    Citation: BioMedical Engineering OnLine 2023 22:25
  21. Heart auscultation is an easy and inexpensive tool for early diagnosis of congenital heart defects. In this regard, a simple device which can be used easily by physicians for heart murmur detection will be ver...

    Authors: Mohammad Reza Khalilian, Mahsa Safari, Mahmoud Hajipour, Khosro Rahmani, Mahmoud Safari, Mohammad Hassan Ahmadpour and Tahmineh Tahouri
    Citation: BioMedical Engineering OnLine 2023 22:24
  22. Exercise electrocardiography (ECG) is a noninvasive test aiming at producing ischemic changes. However, resting ECG cannot be adopted in diagnosing myocardial ischemia till ST-segment depressions. Therefore, t...

    Authors: Chun-Lin Wang, Chiu-Chi Wei, Cheng-Ting Tsai, Ying-Hsiang Lee, Lawrence Yu-Min Liu, Kang-Ying Chen, Yu-Jen Lin and Po-Lin Lin
    Citation: BioMedical Engineering OnLine 2023 22:23
  23. Signal analysis is a domain which is an amalgamation of different processes coming together to form robust pipelines for the automation of data analysis. When applied to the medical world, physiological signal...

    Authors: Anupreet Kaur Singh and Sridhar Krishnan
    Citation: BioMedical Engineering OnLine 2023 22:22
  24. The development and innovation of biomechanical measurement methods provide a solution to the problems in ski jumping research. At present, research on ski jumping mostly focuses on the local technical charact...

    Authors: Jinglun Yu, Xinying Ma, Shuo Qi, Zhiqiang Liang, Zhen Wei, Qi Li, Weiguang Ni, Shutao Wei and Shengnian Zhang
    Citation: BioMedical Engineering OnLine 2023 22:21
  25. The purpose of this study was to compare the biomechanical and clinical results of two surgical methods for the treatment of vertical femoral neck fractures: Femoral neck system (FNS) and traditional three can...

    Authors: Shaolong Huang, Yazhong Zhang, Xu Zhang, Chengqiang Zhou, Wenbo Li, Yunqing Wang, Bin Wang and Ziqiang Zhu
    Citation: BioMedical Engineering OnLine 2023 22:20
  26. Pericardial access is necessary for the application of epicardial cardiac therapies including ablation catheters, pacing and defibrillation leads, and left atrial appendage closure systems. Pericardial access ...

    Authors: Justin D. Opfermann, Jacqueline M. Contento, Paige N. Mass, Axel Krieger, Charles I. Berul and Rohan N. Kumthekar
    Citation: BioMedical Engineering OnLine 2023 22:19
  27. Social isolation (SI) is a state of low social interaction with peers associated with various adverse health consequences in older adults living in the community. SI is most often assessed through retrospectiv...

    Authors: Shehroz S. Khan, Tiancheng Gu, Lauren Spinelli and Rosalie H. Wang
    Citation: BioMedical Engineering OnLine 2023 22:18
  28. This study aimed to develop a pipeline for selecting the best feature engineering-based radiomic path to predict epidermal growth factor receptor (EGFR) mutant lung adenocarcinoma in 18F-fluorodeoxyglucose (FDG) ...

    Authors: Zefeng Liu, Tianyou Zhang, Liying Lin, Fenghua Long, Hongyu Guo and Li Han
    Citation: BioMedical Engineering OnLine 2023 22:17

    The Correction to this article has been published in BioMedical Engineering OnLine 2023 22:32

  29. Fundus fluorescein angiography (FA) can be used to diagnose fundus diseases by observing dynamic fluorescein changes that reflect vascular circulation in the fundus. As FA may pose a risk to patients, generati...

    Authors: Ping Li, Yi He, Pinghe Wang, Jing Wang, Guohua Shi and Yiwei Chen
    Citation: BioMedical Engineering OnLine 2023 22:16
  30. Hydroxyapatite (HAp) possesses osteoconductive properties, and its granular form can serve as an effective drug delivery vehicle for bone regeneration. Quercetin (Qct), a plant-derived bioflavonoid, is known t...

    Authors: Seoyun Lee, Honghyun Park, Jeong-Seop Oh, Kyubin Byun, Dae-Yong Kim, Hui-suk Yun and Byung-Jae Kang
    Citation: BioMedical Engineering OnLine 2023 22:15
  31. A mechanical ankle–foot prosthesis (Talaris Demonstrator) was developed to improve prosthetic gait in people with a lower-limb amputation. This study aims to evaluate the Talaris Demonstrator (TD) during level...

    Authors: Elke Lathouwers, Jean-Pierre Baeyens, Bruno Tassignon, Felipe Gomez, Pierre Cherelle, Romain Meeusen, Bram Vanderborght and Kevin De Pauw
    Citation: BioMedical Engineering OnLine 2023 22:14
  32. The response of soft tissue to loading can be obtained by strain assessment. Typically, strain can be measured using electrical resistance with strain gauges (SG), or optical sensors based on the digital image...

    Authors: Gwendolin Prusa, Leandra Bauer, Inês Santos, Christoph Thorwächter, Matthias Woiczinski and Manuel Kistler
    Citation: BioMedical Engineering OnLine 2023 22:13
  33. Calcium phosphate (Ca-P) bioceramics, including hydroxyapatite (HA), biphasic calcium phosphate (BCP), and beta-tricalcium phosphate (β-TCP), have been widely used in bone reconstruction. Many studies have foc...

    Authors: Pan Jin, Lei Liu, Lin Cheng, Xichi Chen, Shanshan Xi and Tongmeng Jiang
    Citation: BioMedical Engineering OnLine 2023 22:12
  34. Individual motor units have been imaged using ultrafast ultrasound based on separating ultrasound images into motor unit twitches (unfused tetanus) evoked by the motoneuronal spike train. Currently, the spike ...

    Authors: Robin Rohlén, Jonathan Lundsberg and Christian Antfolk
    Citation: BioMedical Engineering OnLine 2023 22:10
  35. Impairments of trunk movements in gait of stroke are often reported. Ankle foot orthosis (AFO) is commonly used to improve gait of stroke; however, the effect of different types of AFOs on the pelvic and thora...

    Authors: Hua Ling, Hui Guo, Hao Zhou, Xiao-Qian Chang, Zi-Yang Guo, Sumiko Yamamoto, Li-Fei Cai and Jun Zhao
    Citation: BioMedical Engineering OnLine 2023 22:9
  36. Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder. It has discriminable appearance. This study was conducted to dig the clinical significance of demographic characteristics and ophthalmologic d...

    Authors: Xiao Huang, Wei Tang, Ya Shen, Linfeng He, Fei Tong, Siyu Liu, Jian Li, Pan Li, Yun Zhang, Xiaoye Ma, Ruili Wei and Weihua Yang
    Citation: BioMedical Engineering OnLine 2023 22:7
  37. The diagnosis of primary membranous nephropathy (PMN) often depends on invasive renal biopsy, and the diagnosis based on clinical manifestations and target antigens may not be completely reliable as it could b...

    Authors: Jie Gao, Siyang Wang, Liang Xu, Jinyan Wang, Jiao Guo, Haiping Wang and Jing Sun
    Citation: BioMedical Engineering OnLine 2023 22:6
  38. Every year, more than 2.5 million critically ill patients in the ICU are dependent on mechanical ventilation. The positive pressure in the lungs generated by the ventilator keeps the diaphragm passive, which c...

    Authors: Elisa M. Kaufmann, Sven Krause, Lukas Geisshuesler, Olivier Scheidegger, Andreas Haeberlin and Thomas Niederhauser
    Citation: BioMedical Engineering OnLine 2023 22:5
  39. People living with dementia often exhibit behavioural and psychological symptoms of dementia that can put their and others’ safety at risk. Existing video surveillance systems in long-term care facilities can...

    Authors: Pratik K. Mishra, Andrea Iaboni, Bing Ye, Kristine Newman, Alex Mihailidis and Shehroz S. Khan
    Citation: BioMedical Engineering OnLine 2023 22:4
  40. People with Parkinson’s disease (PwP) may experience gait impairment and freezing of gait (FOG), a major cause of falls. External cueing, including visual (e.g., spaced lines on the floor) and auditory (e.g., ...

    Authors: Galit Yogev-Seligmann, Naomi Josman, Noemi Bitterman, Sara Rosenblum, Sitar Naaman and Yafit Gilboa
    Citation: BioMedical Engineering OnLine 2023 22:2