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  1. To provide surgical support for corrective osteotomy, we developed an image fusion system for three-dimensional (3D) preoperative planning and fluoroscopy. To assess the utility of this image fusion system, we...

    Authors: Yuichi Yoshii, Takeshi Ogawa, Yuki Hara, Yasukazu Totoki and Tomoo Ishii
    Citation: BioMedical Engineering OnLine 2021 20:66
  2. This study used machine learning classification of texture features from MRI of breast tumor and peri-tumor at multiple treatment time points in conjunction with molecular subtypes to predict eventual patholog...

    Authors: Lal Hussain, Pauline Huang, Tony Nguyen, Kashif J. Lone, Amjad Ali, Muhammad Salman Khan, Haifang Li, Doug Young Suh and Tim Q. Duong
    Citation: BioMedical Engineering OnLine 2021 20:63
  3. Pathological gaits of children may lead to terrible diseases, such as osteoarthritis or scoliosis. By monitoring the gait pattern of a child, proper therapeutic measures can be recommended to avoid the terribl...

    Authors: Linghui Xu, Jiansong Chen, Fei Wang, Yuting Chen, Wei Yang and Canjun Yang
    Citation: BioMedical Engineering OnLine 2021 20:62
  4. The use of machine learning (ML) techniques in healthcare encompasses an emerging concept that envisages vast contributions to the tackling of rare diseases. In this scenario, amyotrophic lateral sclerosis (AL...

    Authors: Felipe Fernandes, Ingridy Barbalho, Daniele Barros, Ricardo Valentim, César Teixeira, Jorge Henriques, Paulo Gil and Mário Dourado Júnior
    Citation: BioMedical Engineering OnLine 2021 20:61
  5. Peripheral nerve injury can cause significant impairment, and the current methods for facilitating repair, particularly over distances greater than approximately 1 mm, are not entirely effective. Allografts, a...

    Authors: Julia Towne, Nicklaus Carter and David J. Neivandt
    Citation: BioMedical Engineering OnLine 2021 20:60
  6. Nebulizers are medical devices that deliver aerosolized medication directly to lungs to treat a variety of respiratory diseases. However, breathing patterns, respiration rates, airway diameters, and amounts of...

    Authors: Hyun Mok Park, Kyung Hwa Chang, Sang-Hyub Moon, Bong Joo Park, Sun Kook Yoo and Ki Chang Nam
    Citation: BioMedical Engineering OnLine 2021 20:59
  7. To explore the analgesic efficacy of extracorporeal shock wave (ESW) combined with percutaneous vertebroplasty (PVP) after reduction in overextension position in the treatment of osteoporotic thoracolumbar com...

    Authors: Xiaowei Liu, Hui Wang, Yang Zhang, Mingling Wang, Yujin Qiu, Xiaodong Sun and Sheng Wang
    Citation: BioMedical Engineering OnLine 2021 20:58
  8. Breast cancer is one of the most serious diseases threatening women’s health. Early screening based on ultrasound can help to detect and treat tumours in the early stage. However, due to the lack of radiologis...

    Authors: Xiaoyan Shen, He Ma, Ruibo Liu, Hong Li, Jiachuan He and Xinran Wu
    Citation: BioMedical Engineering OnLine 2021 20:57
  9. The spinal nerve ligation (SNL) rat is well known as the most common rodent model of neuropathic pain without motor deficit. Researchers have performed analyses using only the von Frey and thermal withdrawal t...

    Authors: Takayuki Seto, Hidenori Suzuki, Tomoya Okazaki, Yasuaki Imajo, Norihiro Nishida, Masahiro Funaba, Tsukasa Kanchiku, Toshihiko Taguchi and Takashi Sakai
    Citation: BioMedical Engineering OnLine 2021 20:55
  10. To develop a novel subjective–objective-combined (SOC) grading standard for auto-segmentation for each organ at risk (OAR) in the thorax.

    Authors: Yanchen Ying, Hao Wang, Hua Chen, Jianfan Cheng, Hengle Gu, Yan Shao, Yanhua Duan, Aihui Feng, Wen Feng, Xiaolong Fu, Hong Quan and Zhiyong Xu
    Citation: BioMedical Engineering OnLine 2021 20:54
  11. Active human body models (AHBM) consider musculoskeletal movement and joint stiffness via active muscle truss elements in the finite element (FE) codes in dynamic application. In the latest models, such as THU...

    Authors: Niclas Trube, Werner Riedel and Matthias Boljen
    Citation: BioMedical Engineering OnLine 2021 20:53
  12. Establishing a high-accuracy and non-invasive method is essential for evaluating cardiovascular disease. Skin cholesterol is a novel marker for assessing the risk of atherosclerosis and can be used as an indep...

    Authors: Jingshu Ni, Haiou Hong, Yang Zhang, Shiqi Tang, Yongsheng Han, Zhaohui Fang, Yuanzhi Zhang, Nan Zhou, Quanfu Wang, Yong Liu, Zhongsheng Li, YiKun Wang and Meili Dong
    Citation: BioMedical Engineering OnLine 2021 20:52
  13. Early detection of laryngeal masses without periodic visits to hospitals is essential for improving the possibility of full recovery and the long-term survival ratio after prompt treatment, as well as reducing...

    Authors: Gun Ho Kim, Eui-Suk Sung and Kyoung Won Nam
    Citation: BioMedical Engineering OnLine 2021 20:51
  14. Parkinson’s disease (PD) is a neurological disease that affects the motor system. The associated motor symptoms are muscle rigidity or stiffness, bradykinesia, tremors, and gait disturbances. The correct diagn...

    Authors: Luciano Brinck Peres, Bruno Coelho Calil, Ana Paula Sousa Paixão Barroso da Silva, Valdeci Carlos Dionísio, Marcus Fraga Vieira, Adriano de Oliveira Andrade and Adriano Alves Pereira
    Citation: BioMedical Engineering OnLine 2021 20:50
  15. Effective maintenance management of medical equipment is one of the major issues for quality of care, for providing cost-effective health services and for saving scarce resources. This study aimed to develop a...

    Authors: Morteza Arab-Zozani, Ali Imani, Leila Doshmangir, Koustuv Dalal and Rona Bahreini
    Citation: BioMedical Engineering OnLine 2021 20:49
  16. Research on the degradation of silk fibroin (SF) scaffolds in vivo lacks uniform and effective standards and experimental evaluation methods. This study aims to evaluate the application of ultrasound in assess...

    Authors: Lihui Cai, Nan Gao, TingYu Sun, Ke Bi, Xin Chen and Xia Zhao
    Citation: BioMedical Engineering OnLine 2021 20:48
  17. Adverse neurological events associated with left ventricular assist devices (LVADs) have been suspected to be related to thrombosis. This study aimed to understand the risks of thrombosis with variations in th...

    Authors: Michael Neidlin, Sam Liao, Zhiyong Li, Benjamin Simpson, David M. Kaye, Ulrich Steinseifer and Shaun Gregory
    Citation: BioMedical Engineering OnLine 2021 20:47
  18. Coronary stents are routinely placed in the treatment and prophylaxis of coronary artery disease (CAD). Current coronary stent designs are prone to developing blockages: in-stent thrombosis (IST) and in-stent ...

    Authors: Joseph Robert Stevens, Ava Zamani, James Ian Atkins Osborne, Reza Zamani and Mohammad Akrami
    Citation: BioMedical Engineering OnLine 2021 20:46
  19. Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming one of the most common liver diseases. Ultrasound elastography has been used for the diagnosis of NAFLD. However, clinical research on steatosis by ...

    Authors: Zhaoke Pi, Mengke Wang, Haoming Lin, Yanrong Guo, Siping Chen, Xianfen Diao, Hui Xia, Guoqiang Liu, Jie Zeng, Xinyu Zhang and Xin Chen
    Citation: BioMedical Engineering OnLine 2021 20:45
  20. Cerebrovascular disease, in particular stroke, is a major public health challenge. An important biomarker is cerebral hemodynamics. To measure and quantify cerebral hemodynamics, however, only invasive, potent...

    Authors: Dietmar Frey, Michelle Livne, Heiko Leppin, Ela M. Akay, Orhun U. Aydin, Jonas Behland, Jan Sobesky, Peter Vajkoczy and Vince I. Madai
    Citation: BioMedical Engineering OnLine 2021 20:44
  21. Recognition of facial expressions (FEs) plays a crucial role in social interactions. Most studies on FE recognition use static (image) stimuli, even though real-life FEs are dynamic. FE processing is complex a...

    Authors: Tuba Aktürk, Tom A. de Graaf, Yasemin Abra, Sevilay Şahoğlu-Göktaş, Dilek Özkan, Aysun Kula and Bahar Güntekin
    Citation: BioMedical Engineering OnLine 2021 20:41
  22. Infertility is a significant problem of humanity. In vitro fertilisation is one of the most effective and frequently applied ART methods. The effectiveness IVF depends on the assessment and selection of gamete...

    Authors: Anna Targosz, Piotr Przystałka, Ryszard Wiaderkiewicz and Grzegorz Mrugacz
    Citation: BioMedical Engineering OnLine 2021 20:40
  23. Small-incision lenticule extraction (SMILE) is a surgical procedure for the refractive correction of myopia and astigmatism, which has been reported as safe and effective. However, over- and under-correction s...

    Authors: Seungbin Park, Hannah Kim, Laehyun Kim, Jin-kuk Kim, In Sik Lee, Ik Hee Ryu and Youngjun Kim
    Citation: BioMedical Engineering OnLine 2021 20:38
  24. Low-dose X-ray images have become increasingly popular in the last decades, due to the need to guarantee the lowest reasonable patient’s exposure. Dose reduction causes a substantial increase of quantum noise,...

    Authors: Emilio Andreozzi, Antonio Fratini, Daniele Esposito, Mario Cesarelli and Paolo Bifulco
    Citation: BioMedical Engineering OnLine 2021 20:36
  25. Coronary plaque vulnerability prediction is difficult because plaque vulnerability is non-trivial to quantify, clinically available medical image modality is not enough to quantify thin cap thickness, predicti...

    Authors: Xiaoya Guo, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Jie Zheng, Habib Samady, Gary S. Mintz, Don P. Giddens and Dalin Tang
    Citation: BioMedical Engineering OnLine 2021 20:34
  26. MXene is a recently emerged multifaceted two-dimensional (2D) material that is made up of surface-modified carbide, providing its flexibility and variable composition. They consist of layers of early transitio...

    Authors: Adibah Zamhuri, Gim Pao Lim, Nyuk Ling Ma, Kian Sek Tee and Chin Fhong Soon
    Citation: BioMedical Engineering OnLine 2021 20:33
  27. Unified Parkinson Disease Rating Scale-part III (UPDRS III) is part of the standard clinical examination performed to track the severity of Parkinson’s disease (PD) motor complications. Wearable technologies c...

    Authors: Murtadha D. Hssayeni, Joohi Jimenez-Shahed, Michelle A. Burack and Behnaz Ghoraani
    Citation: BioMedical Engineering OnLine 2021 20:32
  28. The use of machine learning (ML) methods would improve the diagnosis of respiratory changes in systemic sclerosis (SSc). This paper evaluates the performance of several ML algorithms associated with the respir...

    Authors: Domingos S. M. Andrade, Luigi Maciel Ribeiro, Agnaldo J. Lopes, Jorge L. M. Amaral and Pedro L. Melo
    Citation: BioMedical Engineering OnLine 2021 20:31
  29. The regulation and control of pressure stimuli is useful for many studies of pain and nociception especially those in the visceral pain field. In many in vivo experiments, distinct air and liquid stimuli at va...

    Authors: Michael DeLong, Mauricio Gil-Silva, Veronica Minsu Hong, Olivia Babyok and Benedict J. Kolber
    Citation: BioMedical Engineering OnLine 2021 20:30
  30. As an object’s electrical passive property, the electrical conductivity is proportional to the mobility and concentration of charged carriers that reflect the brain micro-structures. The measured multi-b diffusio...

    Authors: Mun Bae Lee, Hyung Joong Kim and Oh In Kwon
    Citation: BioMedical Engineering OnLine 2021 20:29
  31. The structural changes of gastric mucosa are considered as an important window of early gastric lesions. This article shows an imaging method of the stomach that does not use imaging agents. X-ray phase-contra...

    Authors: Qiang Tao, Chenchen Gao, Xuehong Tong, Shizhen Yuan and Jingdong Xu
    Citation: BioMedical Engineering OnLine 2021 20:28
  32. Lung ultrasound (LUS) can be an important imaging tool for the diagnosis and assessment of lung involvement. Ultrasound sonograms have been confirmed to illustrate damage to a person’s lungs, which means that ...

    Authors: Zhaoyu Hu, Zhenhua Liu, Yijie Dong, Jianjian Liu, Bin Huang, Aihua Liu, Jingjing Huang, Xujuan Pu, Xia Shi, Jinhua Yu, Yang Xiao, Hui Zhang and Jianqiao Zhou
    Citation: BioMedical Engineering OnLine 2021 20:27
  33. Fresh stillbirths (FSB) and very early neonatal deaths (VEND) are important global challenges with 2.6 million deaths annually. The vast majority of these deaths occur in low- and low-middle income countries. ...

    Authors: Jarle Urdal, Kjersti Engan, Trygve Eftestøl, Solveig H. Haaland, Benjamin Kamala, Paschal Mdoe, Hussein Kidanto and Hege Ersdal
    Citation: BioMedical Engineering OnLine 2021 20:26
  34. Electrical pulse stimulations have been applied in brain for treating certain diseases such as movement disorders. High-frequency stimulations (HFS) of biphasic pulses have been used in clinic stimulations, su...

    Authors: Yue Yuan, Lvpiao Zheng, Zhouyan Feng and Gangsheng Yang
    Citation: BioMedical Engineering OnLine 2021 20:25
  35. Osteosarcoma (OS) is the most common primary bone malignancy that affects children and young adults. OS is characterized by a high degree of malignancy, strong invasiveness, rapid disease progression, and extr...

    Authors: Xin Zhao, Qirui Wu, Xiuqing Gong, Jinfeng Liu and Yujie Ma
    Citation: BioMedical Engineering OnLine 2021 20:24
  36. Precise visualization of meshes and their position would greatly aid in mesh shrinkage evaluation, hernia recurrence risk assessment, and the preoperative planning of salvage repair. Lightweight (LW) meshes ar...

    Authors: Jiting Yang, Haiyan Li, Jun Wu, Liang Sun, Dan Xu, Yuanyuan Wang, Yufeng Zhang, Yue Chen and Lin Chen
    Citation: BioMedical Engineering OnLine 2021 20:23
  37. The detection and dissection of epidermal subgroups could lead to an improved understanding of skin homeostasis and wound healing. Flow cytometric analysis provides an effective method to detect the surface ma...

    Authors: Lidan Zhang, Ying Cen, Qiaorong Huang, Huifang Li, Xianming Mo, Wentong Meng and Junjie Chen
    Citation: BioMedical Engineering OnLine 2021 20:22
  38. Over the last decades, microRNAs (miRNAs) have emerged as important molecules associated with the regulation of gene expression in humans and other organisms, expanding the strategies available to diagnose and...

    Authors: Leonardo J. Galvão-Lima, Antonio H. F. Morais, Ricardo A. M. Valentim and Elio J. S. S. Barreto
    Citation: BioMedical Engineering OnLine 2021 20:21
  39. Self-esteem is the individual evaluation of oneself. People with high self-esteem grade have mental health and can bravely cope with the threats from the environment. With the development of neuroimaging techn...

    Authors: Bo Peng, Gaofeng Pang, Aditya Saxena, Yan Liu, Baohua Hu, Suhong Wang and Yakang Dai
    Citation: BioMedical Engineering OnLine 2021 20:20
  40. Cone-shaped vena cava filters (VCFs) are widely used to treat venous thromboembolism. However, in the long term, the problem of occlusion persists even after the filter is deployed. A previous study hypothesiz...

    Authors: Ying Chen, Zaipin Xu, Xiaoyan Deng, Shibo Yang, Wenchang Tan, Yubo Fan, Yong Han and Yubin Xing
    Citation: BioMedical Engineering OnLine 2021 20:19
  41. Advances in regenerative medicine technologies have been strongly proposed in the management of thyroid diseases. Mechanistically, the adoption of thyroid bioengineering requires a scaffold that shares a simil...

    Authors: Jie Weng, Bi Chen, Mengying Xie, Xinlong Wan, Peng Wang, Xiaoming Zhou, Zhiliang Zhou, Jin Mei, Liang Wang, Duping Huang, Zhibin Wang, Zhiyi Wang and Chan Chen
    Citation: BioMedical Engineering OnLine 2021 20:18
  42. Intravascular ultrasound (IVUS) is the golden standard in accessing the coronary lesions, stenosis, and atherosclerosis plaques. In this paper, a fully automatic approach by an 8-layer U-Net is developed to se...

    Authors: Liang Dong, Wenbing Jiang, Wei Lu, Jun Jiang, Ya Zhao, Xiangfen Song, Xiaochang Leng, Hang Zhao, Jian’an Wang, Changling Li and Jianping Xiang
    Citation: BioMedical Engineering OnLine 2021 20:16