Articles
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Citation: BioMedical Engineering OnLine 2005 4:9
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Valentinuzzi ME: Understanding the Human Machine, A Primer for Bioengineering
Citation: BioMedical Engineering OnLine 2005 4:8 -
Gap-junction channels inhibit transverse propagation in cardiac muscle
The effect of adding many gap-junctions (g-j) channels between contiguous cells in a linear chain on transverse propagation between parallel chains was examined in a 5 × 5 model (5 parallel chains of 5 cells e...
Citation: BioMedical Engineering OnLine 2005 4:7 -
Life-threatening ventricular arrhythmia recognition by nonlinear descriptor
Ventricular tachycardia (VT) and ventricular fibrillation (VF) are ventricular cardiac arrhythmia that could be catastrophic and life threatening. Correct and timely detection of VT or VF can save lives.
Citation: BioMedical Engineering OnLine 2005 4:6 -
Design and testing of low intensity laser biostimulator
The non-invasive nature of laser biostimulation has made lasers an attractive alternative in Medical Acupuncture at the last 25 years. However, there is still an uncertainty as to whether they work or their ef...
Citation: BioMedical Engineering OnLine 2005 4:5 -
A case study of type 2 diabetes self-management
It has been established that careful diabetes self-management is essential in avoiding chronic complications that compromise health. Disciplined diet control and regular exercise are the keys for the type 2 di...
Citation: BioMedical Engineering OnLine 2005 4:4 -
Review of "Methods for testing and evaluating survey questionnaires" by S. Presser, et al
Citation: BioMedical Engineering OnLine 2005 4:3 -
A finite element method model to simulate laser interstitial thermo therapy in anatomical inhomogeneous regions
Laser Interstitial ThermoTherapy (LITT) is a well established surgical method. The use of LITT is so far limited to homogeneous tissues, e.g. the liver. One of the reasons is the limited capability of existing...
Citation: BioMedical Engineering OnLine 2005 4:2 -
Evolutionary autonomous agents and the nature of apraxia
Evolutionary autonomous agents are robots or robot simulations whose controller is a dynamical neural network and whose evolution occurs autonomously under the guidance of a fitness function without the detail...
Citation: BioMedical Engineering OnLine 2005 4:1 -
Breath to breadth: Peter Sydenham's introduction to management of engineering design
Citation: BioMedical Engineering OnLine 2004 3:45 -
A quantitative comparison of different methods to detect cardiorespiratory coordination during night-time sleep
The univariate approaches used to analyze heart rate variability have recently been extended by several bivariate approaches with respect to cardiorespiratory coordination. Some approaches are explicitly based...
Citation: BioMedical Engineering OnLine 2004 3:44 -
Friedman L M, Furberg C D, DeMets D L: Fundamentals of Clinical Trials 3rd edition
Citation: BioMedical Engineering OnLine 2004 3:43 -
Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion
Investigation of bioheat transfer problems requires the evaluation of temporal and spatial distributions of temperature. This class of problems has been traditionally addressed using the Pennes bioheat equatio...
Citation: BioMedical Engineering OnLine 2004 3:42 -
Threshold intensity factors as lower boundaries for crack propagation in ceramics
Slow crack growth can be described in a v (crack velocity) versus KI (stress intensity factor) diagram. Slow crack growth in ceramics is attributed to corrosion assisted stress at the crack tip or at any pre-exis...
Citation: BioMedical Engineering OnLine 2004 3:41 -
A two-layered mechanical model of the rat esophagus. Experiment and theory
The function of esophagus is to move food by peristaltic motion which is the result of the interaction of the tissue forces in the esophageal wall and the hydrodynamic forces in the food bolus. The structure o...
Citation: BioMedical Engineering OnLine 2004 3:40 -
Multimodal pressure-flow method to assess dynamics of cerebral autoregulation in stroke and hypertension
This study evaluated the effects of stroke on regulation of cerebral blood flow in response to fluctuations in systemic blood pressure (BP). The autoregulatory dynamics are difficult to assess because of the n...
Citation: BioMedical Engineering OnLine 2004 3:39 -
Decrease of resistance to air flow with nasal strips as measured with the airflow perturbation device
Nasal strips are used by athletes, people who snore, and asthmatics to ease the burden of breathing. Although there are some published studies that demonstrate higher flow with nasal strips, none had directly ...
Citation: BioMedical Engineering OnLine 2004 3:38 -
Assessment of the dynamics of atrial signals and local atrial period series during atrial fibrillation: effects of isoproterenol administration
The autonomic nervous system (ANS) plays an important role in the genesis and maintenance of atrial fibrillation (AF), but quantification of its electrophysiologic effects is extremely complex and difficult. A...
Citation: BioMedical Engineering OnLine 2004 3:37 -
Review of, "Biostatistics and Epidemiology" by S. Wassertheil-Smoller
Citation: BioMedical Engineering OnLine 2004 3:36 -
Image fusion for dynamic contrast enhanced magnetic resonance imaging
Multivariate imaging techniques such as dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) have been shown to provide valuable information for medical diagnosis. Even though these techniques provid...
Citation: BioMedical Engineering OnLine 2004 3:35 -
Review and standardization of cell phone exposure calculations using the SAM phantom and anatomically correct head models
We reviewed articles using computational RF dosimetry to compare the Specific Anthropomorphic Mannequin (SAM) to anatomically correct models of the human head. Published conclusions based on such comparisons h...
Citation: BioMedical Engineering OnLine 2004 3:34 -
Moorhouse M Barry P Bioinformatics Biocomputing and Perl
Citation: BioMedical Engineering OnLine 2004 3:33 -
Feasibility of rapid and automated importation of 3D echocardiographic left ventricular (LV) geometry into a finite element (FEM) analysis model
Finite element method (FEM) analysis for intraoperative modeling of the left ventricle (LV) is presently not possible. Since 3D structural data of the LV is now obtainable using standard transesophageal echoca...
Citation: BioMedical Engineering OnLine 2004 3:32 -
ImageParser: a tool for finite element generation from three-dimensional medical images
The finite element method (FEM) is a powerful mathematical tool to simulate and visualize the mechanical deformation of tissues and organs during medical examinations or interventions. It is yet a challenge to...
Citation: BioMedical Engineering OnLine 2004 3:31 -
Analysis of cardiac signals using spatial filling index and time-frequency domain
Analysis of heart rate variation (HRV) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system (ANS). HRV analysis is based on the concept that fast fluctuations may ...
Citation: BioMedical Engineering OnLine 2004 3:30 -
Facilitating arrhythmia simulation: the method of quantitative cellular automata modeling and parallel running
Many arrhythmias are triggered by abnormal electrical activity at the ionic channel and cell level, and then evolve spatio-temporally within the heart. To understand arrhythmias better and to diagnose them mor...
Citation: BioMedical Engineering OnLine 2004 3:29 -
Real time electrocardiogram QRS detection using combined adaptive threshold
QRS and ventricular beat detection is a basic procedure for electrocardiogram (ECG) processing and analysis. Large variety of methods have been proposed and used, featuring high percentages of correct detectio...
Citation: BioMedical Engineering OnLine 2004 3:28 -
Thermal modeling of lesion growth with radiofrequency ablation devices
Temperature is a frequently used parameter to describe the predicted size of lesions computed by computational models. In many cases, however, temperature correlates poorly with lesion size. Although many stud...
Citation: BioMedical Engineering OnLine 2004 3:27 -
Multi-component based cross correlation beat detection in electrocardiogram analysis
The first stage in computerised processing of the electrocardiogram is beat detection. This involves identifying all cardiac cycles and locating the position of the beginning and end of each of the identifiabl...
Citation: BioMedical Engineering OnLine 2004 3:26 -
An active electrode for biopotential recording from small localized bio-sources
Laser bio-stimulation is a well-established procedure in Medical Acupuncture. Nevertheless there is still a confusion as to whether it works or the effect is just placebo. Although a plethora of scientific pap...
Citation: BioMedical Engineering OnLine 2004 3:25 -
Heart rate analysis in normal subjects of various age groups
Analysis of heart rate variation (HRV) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system (ANS). HRV analysis is based on the concept that fast fluctuations may ...
Citation: BioMedical Engineering OnLine 2004 3:24 -
Mechanical properties of the porcine bile duct wall
The function of the common bile duct is to transport bile from the liver and the gall bladder to the duodenum. Since the bile duct is a distensible tube consisting mainly of connective tissue, it is important ...
Citation: BioMedical Engineering OnLine 2004 3:23 -
In Memoriam: Ivan Daskalov: 1933 – 2004
Ivan Daskalov [1933–2004] was a friend who will be missed by many. Neither the quality of a man nor the concept of a friendship can be defined with words. We may only say that both will be missed.
Citation: BioMedical Engineering OnLine 2004 3:22 -
A decision tree – based method for the differential diagnosis of Aortic Stenosis from Mitral Regurgitation using heart sounds
New technologies like echocardiography, color Doppler, CT, and MRI provide more direct and accurate evidence of heart disease than heart auscultation. However, these modalities are costly, large in size and op...
Citation: BioMedical Engineering OnLine 2004 3:21 -
A mathematical model for the burden of diabetes and its complications
The incidence and prevalence of diabetes are increasing all over the world. Complications of diabetes constitute a burden for the individuals and the whole society.
Citation: BioMedical Engineering OnLine 2004 3:20 -
Quantitative assessment of pain-related thermal dysfunction through clinical digital infrared thermal imaging
The skin temperature distribution of a healthy human body exhibits a contralateral symmetry. Some nociceptive and most neuropathic pain pathologies are associated with an alteration of the thermal distribution...
Citation: BioMedical Engineering OnLine 2004 3:19 -
A two-dimensional mathematical model of percutaneous drug absorption
When a drug is applied on the skin surface, the concentration of the drug accumulated in the skin and the amount of the drug eliminated into the blood vessel depend on the value of a parameter, r. The values of r
Citation: BioMedical Engineering OnLine 2004 3:18 -
Simultaneous storage of medical images in the spatial and frequency domain: A comparative study
Digital watermarking is a technique of hiding specific identification data for copyright authentication. This technique is adapted here for interleaving patient information with medical images, to reduce stora...
Citation: BioMedical Engineering OnLine 2004 3:17 -
BioMedical Engineering OnLine: An Editorial
Citation: BioMedical Engineering OnLine 2004 3:16 -
Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism
A computational model of myocardial energy metabolism was used to assess the metabolic responses to normal and reduced myocardial blood flow. The goal was to examine to what extent glycolysis and lactate forma...
Citation: BioMedical Engineering OnLine 2004 3:15 -
Blunt trauma to large vessels: a mathematical study
Blunt trauma causes short-term compression of some or all parts of the chest, abdomen or pelvis and changes hemodynamics of the blood. Short-term compression caused by trauma also results in a short-term decre...
Citation: BioMedical Engineering OnLine 2004 3:14 -
Physiological basis and image processing in functional magnetic resonance imaging: Neuronal and motor activity in brain
Functional magnetic resonance imaging (fMRI) is recently developing as imaging modality used for mapping hemodynamics of neuronal and motor event related tissue blood oxygen level dependence (BOLD) in terms of...
Citation: BioMedical Engineering OnLine 2004 3:13 -
Formulation of photon diffusion from spherical bioluminescent sources in an infinite homogeneous medium
The bioluminescent enzyme firefly luciferase (Luc) or variants of green fluorescent protein (GFP) in transformed cells can be effectively used to reveal molecular and cellular features of neoplasia in vivo. Tumor...
Citation: BioMedical Engineering OnLine 2004 3:12 -
Biological effects of exposure to magnetic resonance imaging: an overview
The literature on biological effects of magnetic and electromagnetic fields commonly utilized in magnetic resonance imaging systems is surveyed here. After an introduction on the basic principles of magnetic r...
Citation: BioMedical Engineering OnLine 2004 3:11 -
Ultra-structural cell distribution of the melanoma marker iodobenzamide: improved potentiality of SIMS imaging in life sciences
Analytical imaging by secondary ion mass spectrometry (SIMS) provides images representative of the distribution of a specific ion within a sample surface. For the last fifteen years, concerted collaborative re...
Citation: BioMedical Engineering OnLine 2004 3:10 -
Safety assessment of near infrared light emitting diodes for diffuse optical measurements
Near infrared (NIR) light has been used widely to monitor important hemodynamic parameters in tissue non-invasively. Pulse oximetry, near infrared spectroscopy, and diffuse optical tomography are examples of s...
Citation: BioMedical Engineering OnLine 2004 3:9 -
Low temperature method for the production of calcium phosphate fillers
Calcium phosphate manufactured samples, prepared with hydroxyapatite, are used as either spacers or fillers in orthopedic surgery, but these implants have never been used under conditions of mechanical stress....
Citation: BioMedical Engineering OnLine 2004 3:8 -
Nonlinear analysis of EEG signals at different mental states
The EEG (Electroencephalogram) is a representative signal containing information about the condition of the brain. The shape of the wave may contain useful information about the state of the brain. However, th...
Citation: BioMedical Engineering OnLine 2004 3:7 -
Thermodynamic phase plane analysis of ventricular contraction and relaxation
Ventricular function has conventionally been characterized using indexes of systolic (contractile) or diastolic (relaxation/stiffness) function. Systolic indexes include maximum elastance or equivalently the e...
Citation: BioMedical Engineering OnLine 2004 3:6 -
Transverse propagation of action potentials between parallel chains of cardiac muscle and smooth muscle cells in PSpice simulations
We previously examined transverse propagation of action potentials between 2 and 3 parallel chain of cardiac muscle cells (CMC) simulated using the PSpice program. The present study was done to examine transve...
Citation: BioMedical Engineering OnLine 2004 3:5