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  1. A challenging problem in current systems biology is that of parameter inference in biological pathways expressed as coupled ordinary differential equations (ODEs). Conventional methods that repeatedly numerica...

    Authors: Benn Macdonald, Mu Niu, Simon Rogers, Maurizio Filippone and Dirk Husmeier
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):80
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  3. Several studies have estimated the potential economic and social impact of the mHealth development. Considering the latest study by Institute for Healthcare Informatics, more than 165.000 apps of health and me...

    Authors: Guillermo Molina Recio, Laura García-Hernández, Rafael Molina Luque and Lorenzo Salas-Morera
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):77
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  4. The provision of health and wellness care is undergoing an enormous transformation. A key element of this revolution consists in prioritizing prevention and proactivity based on the analysis of people’s conduc...

    Authors: Oresti Banos, Muhammad Bilal Amin, Wajahat Ali Khan, Muhammad Afzal, Maqbool Hussain, Byeong Ho Kang and Sungyong Lee
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):76
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  5. One of the main challenges in modern science is the amount of data produced by the experimental work; it is difficult to store, organize and share the scientific data and to extract the wealth of knowledge. Ex...

    Authors: Petr Cisar, Dmytro Soloviov, Antonin Barta, Jan Urban and Dalibor Stys
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):74
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  6. Brain-computer interfacing (BCI) applications based on the classification of electroencephalographic (EEG) signals require solving high-dimensional pattern classification problems with such a relatively small ...

    Authors: Julio Ortega, Javier Asensio-Cubero, John Q. Gan and Andrés Ortiz
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):73
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  7. Aligning multiple sequences arises in many tasks in Bioinformatics. However, the alignments produced by the current software packages are highly dependent on the parameters setting, such as the relative import...

    Authors: Maryam Abbasi, Luís Paquete and Francisco B. Pereira
    Citation: BioMedical Engineering OnLine 2016 15(Suppl 1):70
    Content type: Research Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  8. There is a lack of understanding of the morphological characteristics of the cartilage-bone interface. Materials that are currently being used in tissue engineering do not adequately support the regeneration o...

    Authors: Weiguo Bian, Qin Lian, Dichen Li, Jin Wang, Weijie Zhang, Zhongmin Jin and Yusheng Qiu
    Citation: BioMedical Engineering OnLine 2016 15:82
    Content type: Research Published on:

  9. We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scan...

    Authors: Baran Komur, Tim Lohse, Hatice Merve Can, Gulnar Khalilova, Zeynep Nur Geçimli, Mehmet Onur Aydoğdu, Cevriye Kalkandelen, George E. Stan, Yesim Muge Sahin, Ahmed Zeki Sengil, Mediha Suleymanoglu, Serap Erdem Kuruca, Faik Nuzhet Oktar, Serdar Salman, Nazmi Ekren, Anton Ficai…
    Citation: BioMedical Engineering OnLine 2016 15:81
    Content type: Research Published on:

  10. People with internet addiction (IA) suffer from mental, physical, social, and occupational problems. IA includes psychological and physiological syndromes, and among the syndromes, emotion was suggested import...

    Authors: Dai-Ling Hsieh and Tzu-Chien Hsiao
    Citation: BioMedical Engineering OnLine 2016 15:69
    Content type: Research Published on:

  12. The mechanism underlying atherosclerotic ischemic events within the middle cerebral artery (MCA) is unclear. High structural stress induced by blood pressure might be a potential aetiology as plaque rupture oc...

    Authors: Yuanliang Jiang, Wenjia Peng, Zhongzhao Teng, Jonathan H. Gillard, Bo Hong, Qi Liu and Jianping Lu
    Citation: BioMedical Engineering OnLine 2016 15:67
    Content type: Research Published on:

  13. In order to reduce the radiation dose of CT (computed tomography), compressed sensing theory has been a hot topic since it provides the possibility of a high quality recovery from the sparse sampling data. Rec...

    Authors: Cheng Zhang, Tao Zhang, Ming Li, Chengtao Peng, Zhaobang Liu and Jian Zheng
    Citation: BioMedical Engineering OnLine 2016 15:66
    Content type: Research Published on:

  14. Multi-channel recording of surface electromyographyic (EMG) signals is very likely to be contaminated by electrocardiographic (ECG) interference, specifically when the surface electrode is placed on muscles cl...

    Authors: Maoqi Chen, Xu Zhang, Xiang Chen, Mingxing Zhu, Guanglin Li and Ping Zhou
    Citation: BioMedical Engineering OnLine 2016 15:65
    Content type: Research Published on:

  15. In the activated sludge process, problems of filamentous bulking and foaming can occur due to overgrowth of certain filamentous bacteria. Nowadays, these microorganisms are typically monitored by means of ligh...

    Authors: Philipe A. Dias, Thiemo Dunkel, Diego A. S. Fajado, Erika de León Gallegos, Martin Denecke, Philipp Wiedemann, Fabio K. Schneider and Hajo Suhr
    Citation: BioMedical Engineering OnLine 2016 15:64
    Content type: Research Published on:

  16. Corneal tensile strain increases if the cornea becomes thin or if intraocular pressure increases. However, the effects of mechanical stress on extracellular matrix (ECM) remodelling in the corneal repair proce...

    Authors: Pengfei Feng, Xiaona Li, Weiyi Chen, Chengxing Liu, Shuo Rong, Xiaojun Wang and Genlai Du
    Citation: BioMedical Engineering OnLine 2016 15:63
    Content type: Research Published on:

  17. Robot-based joint-testing systems (RJTS) can be used to perform unconstrained laxity tests, measuring the stiffness of a degree of freedom (DOF) of the joint at a fixed flexion angle while allowing the other D...

    Authors: Hong-Jung Hsieh, Chih-Chung Hu, Tung-Wu Lu, Hsuan-Lun Lu, Mei-Ying Kuo, Chien-Chung Kuo and Horng-Chaung Hsu
    Citation: BioMedical Engineering OnLine 2016 15:62
    Content type: Research Published on:

  18. Pre-impact fall detection has been proposed to be an effective fall prevention strategy. In particular, it can help activate on-demand fall injury prevention systems (e.g. inflatable hip protectors) prior to f...

    Authors: Xinyao Hu and Xingda Qu
    Citation: BioMedical Engineering OnLine 2016 15:61
    Content type: Review Published on:

  19. Intra-Body Communication (IBC), which utilizes the human body as the transmission medium to transmit signal, is a potential communication technique for the physiological data transfer among the sensors of remo...

    Authors: Xi Mei Chen, Sio Hang Pun, Jian Feng Zhao, Peng Un Mak, Bo Dong Liang and Mang I. Vai
    Citation: BioMedical Engineering OnLine 2016 15:60
    Content type: Research Published on:

  20. The photo-thermal effect has been hypothesised to be one of the most possible biophysical mechanisms for laser-cochlea stimulation. However, there is a lack of studies to date for direct assessing laser heatin...

    Authors: Kaiyin Zhang, Yulong Zhang, Ji Li and Qiuling Wang
    Citation: BioMedical Engineering OnLine 2016 15:59
    Content type: Research Published on:

  21. Robot-assisted laparoscopic surgery offers several advantages compared with open surgery and conventional minimally invasive surgery. However, one issue that needs to be resolved is a collision between the rob...

    Authors: Myungjoon Kim, Chiwon Lee, Woo Jung Park, Yun Suhk Suh, Han Kwang Yang, H. Jin Kim and Sungwan Kim
    Citation: BioMedical Engineering OnLine 2016 15:58
    Content type: Research Published on:

  25. This article is a review of the book “Biomagnetics: Principles and Applications of Biomagnetic Stimulation and Imaging” (ISBN 978-1-4822-3920-1, 343 pages) edited by Shoogo Ueno and Masaki Sekino published by ...

    Authors: Pere J. Riu
    Citation: BioMedical Engineering OnLine 2016 15:55
    Content type: Book review Published on:

  26. Denoising is the primary preprocessing step for subsequent application of MRI. However, most commonly-used patch-based denoising methods are heavily dependent on the degree of patch matching. Due to the large ...

    Authors: Xi Wu, Zhipeng Yang, Jing Peng and Jiliu Zhou
    Citation: BioMedical Engineering OnLine 2016 15:54
    Content type: Research Published on:

  27. Accurate blood pressure (BP) measurement depends on the reliability of oscillometric cuff pressure pulses (OscP) and Korotkoff sounds (KorS) for automated oscillometric and manual techniques. It has been widel...

    Authors: Diliang Chen, Fei Chen, Alan Murray and Dingchang Zheng
    Citation: BioMedical Engineering OnLine 2016 15:53
    Content type: Research Published on:

  28. Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associated...

    Authors: Luis F. Giraldo-Cadavid, Luis Mauricio Agudelo-Otalora, Javier Burguete, Mario Arbulu, William Daniel Moscoso, Fabio Martínez, Andrés Felipe Ortiz, Juan Diaz, Jaime A. Pantoja, Andrés Felipe Rueda-Arango and Secundino Fernández
    Citation: BioMedical Engineering OnLine 2016 15:52
    Content type: Research Published on:

  30. Reconstruction of patient-specific biomechanical model of intracranial aneurysm has been based on different imaging modalities. However, different imaging techniques may influence the model geometry and the co...

    Authors: Yuan Ren, Guo-Zhong Chen, Zhen Liu, Yan Cai, Guang-Ming Lu and Zhi-Yong Li
    Citation: BioMedical Engineering OnLine 2016 15:50
    Content type: Research Published on:

  31. Pulmonary nodules in computerized tomography (CT) images are potential manifestations of lung cancer. Segmentation of potential nodule objects is the first necessary and crucial step in computer-aided detectio...

    Authors: Bin Li, QingLin Chen, Guangming Peng, Yuanxing Guo, Kan Chen, LianFang Tian, Shanxing Ou and Lifei Wang
    Citation: BioMedical Engineering OnLine 2016 15:49
    Content type: Research Published on:

  32. Stress calculations in atherosclerotic coronary vulnerable plaques can aid in predicting coronary cap rupture. In vivo plaque geometry and composition of coronary arteries can merely be obtained via intravascu...

    Authors: Annette M. Kok, Lambert Speelman, Renu Virmani, Antonius F. W. van der Steen, Frank J. H. Gijsen and Jolanda J. Wentzel
    Citation: BioMedical Engineering OnLine 2016 15:48
    Content type: Research Published on:

  33. Colour is the most important feature used in quantitative immunohistochemistry (IHC) image analysis; IHC is used to provide information relating to aetiology and to confirm malignancy.

    Authors: Jie Shu, G. E. Dolman, Jiang Duan, Guoping Qiu and Mohammad Ilyas
    Citation: BioMedical Engineering OnLine 2016 15:46
    Content type: Research Published on:

  35. Electrogram-guided ablation procedures have been proposed as an alternative strategy consisting of either mapping and ablating focal sources or targeting complex fractionated electrograms in atrial fibrillatio...

    Authors: Andres Orozco-Duque, John Bustamante and German Castellanos-Dominguez
    Citation: BioMedical Engineering OnLine 2016 15:44
    Content type: Research Published on:

  37. A biofeedback-based balance training system can be used to provide the compromised sensory information to subjects in order to retrain their sensorimotor function. In this study, the design and evaluation of t...

    Authors: Muhammad Raheel Afzal, Min-Kyun Oh, Hye Young Choi and Jungwon Yoon
    Citation: BioMedical Engineering OnLine 2016 15:42
    Content type: Research Published on:

  38. Recently, two-dimensional techniques have been successfully employed for compressing surface electromyographic (SEMG) records as images, through the use of image and video encoders. Such schemes usually provid...

    Authors: Wheidima Carneiro de Melo, Eddie Batista de Lima Filho and Waldir Sabino da Silva Júnior
    Citation: BioMedical Engineering OnLine 2016 15:41
    Content type: Research Published on:

  40. Accurate segmentation of anatomical structures in medical images is a critical step in the development of computer assisted intervention systems. However, complex image conditions, such as intensity inhomogene...

    Authors: Kuanquan Wang and Chao Ma
    Citation: BioMedical Engineering OnLine 2016 15:39
    Content type: Research Published on:

  41. Dominant frequency (DF) analysis of atrial electrograms has become an important method in characterizing atrial fibrillation (AF). As a classic method, Botteron’s approach is widely used in the preprocessing o...

    Authors: Wenhai Li, Cuiwei Yang, Yanlei Wang, Dexi Wang, Ying Chen and Zhong Wu
    Citation: BioMedical Engineering OnLine 2016 15:38
    Content type: Research Published on:

  42. Patient-specific simulations can provide insight into the mechanics of cardiovascular procedures. Amongst cardiovascular devices, non-compliant balloons are used in several minimally invasive procedures, such ...

    Authors: Benedetta Biffi, Giorgia M. Bosi, Valentina Lintas, Rod Jones, Spyros Tzamtzis, Gaetano Burriesci, Francesco Migliavacca, Andrew M. Taylor, Silvia Schievano and Giovanni Biglino
    Citation: BioMedical Engineering OnLine 2016 15:37
    Content type: Research Published on:

  43. Electroporation-based applications require multidisciplinary expertise and collaboration of experts with different professional backgrounds in engineering and science. Beginning in 2003, an international scien...

    Authors: Selma Čorović, Samo Mahnič-Kalamiza and Damijan Miklavčič
    Citation: BioMedical Engineering OnLine 2016 15:36
    Content type: Research Published on:

  45. Ventricle material properties are difficult to obtain under in vivo conditions and are not readily available in the current literature. It is also desirable to have an initial determination if a patient had an...

    Authors: Longling Fan, Jing Yao, Chun Yang, Zheyang Wu, Di Xu and Dalin Tang
    Citation: BioMedical Engineering OnLine 2016 15:34
    Content type: Research Published on:

  47. Spine magnetic resonance image (MRI) plays a very important role in the diagnosis of various spinal diseases, such as disc degeneration, scoliosis, and osteoporosis. Accurate localization and segmentation of t...

    Authors: Xinjian Zhu, Xuan He, Pin Wang, Qinghua He, Dandan Gao, Jiwei Cheng and Baoming Wu
    Citation: BioMedical Engineering OnLine 2016 15:32
    Content type: Research Published on:

  48. Urethral pressure profilometry (UPP) is used in the diagnosis of stress urinary incontinence (SUI) which is a significant medical, social, and economic problem. Low spatial pressure resolution, common occurren...

    Authors: Mario Klünder, Oliver Sawodny, Bastian Amend, Michael Ederer, Alexandra Kelp, Karl-Dietrich Sievert, Arnulf Stenzl and Ronny Feuer
    Citation: BioMedical Engineering OnLine 2016 15:31
    Content type: Research Published on:

  50. Using of active cardiac medical devices increases steadily. In Europe, there were 183 implants of ICD and 944 implants of PM, 119 of biventricular ICD and 41 of biventricular PM, all per million inhabitants in...

    Authors: Martin Augustynek, David Korpas, Marek Penhaker, Jakub Cvek and Andrea Binarova
    Citation: BioMedical Engineering OnLine 2016 15:29
    Content type: Research Published on:
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