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Volume 15 Supplement 2

Computational and Experimental Methods for Biological Research: Cardiovascular Diseases and Beyond

Research

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The peer review process was overseen by the Supplement Editors in accordance with BioMed Central's peer review guidelines for supplements. The Supplement Editors declare that they were not involved in the peer review for articles on which they are authors. They declare no other competing interests.

Edited by Dalin Tang and Zhi-Yong Li.

  1. Content type: Research

    This study specifically focused on anatomical MRI characterization of the low shear stress-induced atherosclerotic plaque in mice. We used machine learning algorithms to analyze multiple correlation factors of...

    Authors: Bing Li, Yun Jiao, Cong Fu, Bo Xie, Genshan Ma, Gaojun Teng and Yuyu Yao

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):146

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  2. Content type: Research

    Simultaneous measurement of four-limb blood pressures can improve the accuracy of cardiovascular disease diagnosis. This study aims to investigate the association of simultaneously measured four-limb blood pre...

    Authors: Xiaorui Song, Gaoyang Li, Aike Qiao and Zhihui Chen

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):147

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  3. Content type: Research

    Mechanical load-induced intraosseous pressure gradients may result in some fluid stimuli effects, such as fluid flow and fluid shear stress (FSS), which may enable bone cells to detect external mechanical sign...

    Authors: Xiaogang Wu, Ningning Wang, Zhaowei Wang, Weilun Yu, Yanqin Wang, Yuan Guo and Weiyi Chen

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):149

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  4. Content type: Research

    In stent design optimization, the functional relationship between design parameters and design goals is nonlinear, complex, and implicit and the multi-objective design of stents involves a number of potentiall...

    Authors: Hongxia Li, Junfeng Gu, Minjie Wang, Danyang Zhao, Zheng Li, Aike Qiao and Bao Zhu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):148

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  5. Content type: Research

    Left ventricular assist device (LVAD) has become an alternative treatment for end-stage heart failure patients. Series type of LVAD, as a novel LVAD, has attracted more and more attention. The hemodynamic effe...

    Authors: Qi Zhang, Bin Gao and Yu Chang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):163

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  6. Content type: Research

    Knee valgus and varus morbidity is at the second top place in children lower limb deformity diseases. It may cause abnormal stress distribution. The magnitude and location of contact forces on tibia plateau du...

    Authors: Jun Sun, Songhua Yan, Yan Jiang, Duo Wai-chi Wong, Ming Zhang, Jizhou Zeng and Kuan Zhang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):158

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  7. Content type: Research

    The intraocular pressure (IOP) is maintained through a dynamic equilibrium between the production and drainage of aqueous humor. Elevation of intraocular pressure is mainly caused by the blocking of aqueous hu...

    Authors: Jing Zhang, Lin Ren, Xi Mei, Qiang Xu, Wei Zheng and Zhicheng Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):162

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  8. Content type: Research

    Mental arithmetic has been verified inducing cerebral and cardiovascular responses. However, the mechanism and sequential responses are still ambiguous. This study aims to reveal the mechanism of cardiovascula...

    Authors: Xiaoni Wang, Binbin Liu, Lin Xie, Xiaolin Yu, Mengjun Li and Jianbao Zhang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):160

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  9. Content type: Research

    Blood continuously flows through the blood vessels in the human body. When blood flows through the smallest blood vessels, red blood cells (RBCs) in the blood exhibit various types of motion and deformed shape...

    Authors: Hasitha-Nayanajith Polwaththe-Gallage, Suvash C. Saha, Emilie Sauret, Robert Flower, Wijitha Senadeera and YuanTong Gu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):161

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  10. Content type: Research

    Flow diverter (FD) intervention is an emerging endovascular technique for treating intracranial aneurysms. High flow-diversion efficiency is desired to accelerate thrombotic occlusion inside the aneurysm; howe...

    Authors: Mingzi Zhang, Hitomi Anzai, Bastien Chopard and Makoto Ohta

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):159

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  11. Content type: Research

    Basilar invagination (BI) combined with atlantoaxial dislocation (AAD) leads to foramen magnum stenosis and medullary spinal cord compression, causing nerve dysfunction. The purpose of the surgery is to remove...

    Authors: Xuefeng Bo, Weida Wang, Zan Chen and Zhicheng Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):168

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  12. Content type: Research

    Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main...

    Authors: Jie Li, Xiaopeng Tian, Zhenze Wang, Jiang Xiong, Yubo Fan, Xiaoyan Deng, Anqiang Sun and Xiao Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):135

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  13. Content type: Research

    Endovascular intervention using a stent is a mainstream treatment for cerebral aneurysms. To assess the effect of intervention strategies on aneurysm hemodynamics, we have developed a fast virtual stenting (FV...

    Authors: Qianqian Zhang, Zhuangyuan Meng, Ying Zhang, Kai Yao, Jian Liu, Yisen Zhang, Linkai Jing, Xinjian Yang, Nikhil Paliwal, Hui Meng and Shengzhang Wang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):125

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  14. Content type: Research

    The multi-contrast assessment of the carotid artery wall has become an important diagnostic tool for the characterization of atherosclerotic plaque and vessel wall thickening. For providing the required T1-, T...

    Authors: Jian Zhu, Axel Bornstedt, Nico Merkle, Naifeng Liu, Wolfgang Rottbauer, Genshan Ma and Volker Rasche

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):165

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  15. Content type: Research

    Patients with multiple intracranial aneurysms present a great challenge to the neurosurgeon, particularly when presenting with subarachnoid hemorrhage. Misjudgment may result in disastrous postoperative reblee...

    Authors: Lijian Xu, Lixu Gu and Hao Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):166

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  16. Content type: Research

    The anatomical configurations of respiratory tract would be directly associated with their ventilatory function. It is necessary to fully understand the association between airway configurations and their func...

    Authors: Shen Yu, Jizhe Wang, Xiuzhen Sun and Yingxi Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):164

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  17. Content type: Research

    Pulleys have been reported as the functional origins of the rectus extraocular muscles (EOMs). However, biomechanical significance of pulleys on binocular vision has not been reported.

    Authors: Hongmei Guo, Zhipeng Gao and Weiyi Chen

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):137

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  18. Content type: Research

    PM2.5 is an important factor to affect the patients with respiratory and cardiovascular diseases. Clinical studies have found that the morbidity and mortality of patients with heart failure (HF) have a close r...

    Authors: Tiantian Zhang, Bin Gao, Zhixiang Zhou and Yu Chang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):138

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  19. Content type: Research

    This study is to investigate the influence of hemodynamics on Stanford type-A aortic dissection with different tear size and location, to provide some support for the relationships between the risks (rupture, ...

    Authors: Yue Shi, Minjia Zhu, Yu Chang, Huanyu Qiao and Yongmin Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):128

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  20. Content type: Research

    Sequential and single grafting are two surgical procedures of coronary artery bypass grafting. However, it remains unclear if the sequential graft can be used between the right and left coronary artery system....

    Authors: Wenxin Wang, Boyan Mao, Haoran Wang, Xueying Geng, Xi Zhao, Huixia Zhang, Jinsheng Xie, Zhou Zhao, Bo Lian and Youjun Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):132

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  21. Content type: Research

    During coronary artery bypass grafting (CABG), the ratio of powers of the fundamental frequency and its first harmonic (F0/H1) in fast Fourier transformation (FFT) analysis of the graft’s flow waves has been u...

    Authors: Boyan Mao, Wenxin Wang, Zhou Zhao, Xi Zhao, Lanlan Li, Huixia Zhang and Youjun Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):129

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  22. Content type: Research

    Glaucoma is the primary cause of irreversible blindness worldwide associated with high intraocular pressure (IOP). Elevated intraocular pressure will affect the normal aqueous humor outflow, resulting in defor...

    Authors: Wenjia Wang, Xiuqing Qian, Hongfang Song, Mindi Zhang and Zhicheng Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):133

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    The Erratum to this article has been published in BioMedical Engineering OnLine 2017 16:22

  23. Content type: Research

    Implantation of a rotary blood pump (RBP) can cause non-physiological flow fields in the left ventricle (LV) which may trigger thrombosis. Different inflow cannula geometry can affect LV flow fields. The aim o...

    Authors: Sam Liao, Benjamin Simpson, Michael Neidlin, Tim A. S. Kaufmann, Zhiyong Li, Maria A. Woodruff and Shaun D. Gregory

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):136

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  24. Content type: Research

    Keratinocyte (KC) migration in re-epithelization is crucial in repairing injured skin. But the mechanisms of how mechanical stimuli regulate the migration of keratinocytes have been poorly understood.

    Authors: Dongyuan Lü, Zhan Li, Yuxin Gao, Chunhua Luo, Fan Zhang, Lu Zheng, Jiawen Wang, Shujin Sun and Mian Long

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):130

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  25. Content type: Research

    Wall shear stress (WSS) is involved in the pathophysiology of atherosclerosis. The correlation between WSS and atherosclerosis can be investigated over time using a WSS-manipulated atherosclerotic mouse model....

    Authors: Ruoyu Xing, David De Wilde, Gayle McCann, Yanto Ridwan, Jelle T. C. Schrauwen, Anton F. W. van der Steen, Frank J. H. Gijsen and Kim Van der Heiden

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):156

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  26. Content type: Research

    Binding of P-selectin to P-selectin glycoprotein ligand-1 (PSGL-1) makes neutrophils roll on and adhere to inflammatory site. Intracellular calcium bursting of adhered neutrophils is a key event for subsequent...

    Authors: Bing Huang, Yingchen Ling, Jiangguo Lin, Ying Fang and Jianhua Wu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):153

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  27. Content type: Research

    Interaction between immunoglobulin-like receptor glycoprotein VI (GPVI) and collagen plays a central role in platelet activation and sequent firm adhesion. Of various antithrombotic agents targeting GPVI, anti...

    Authors: Wenping Liu, Guangjian Liu, Huiyun Zhou, Xiang Fang, Ying Fang and Jianhua Wu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):152

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  28. Content type: Research

    In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand ho...

    Authors: Yan-Xia Wang, Cheng Xiang, Bo Liu, Yong Zhu, Yong Luan, Shu-Tian Liu and Kai-Rong Qin

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):154

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  29. Content type: Research

    Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-...

    Authors: Wen-Xue Yuan, Hai-Bin Liu, Feng-Shan Gao, Yan-Xia Wang and Kai-Rong Qin

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):151

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