An active compression bandage based on shape memory alloys: a preliminary investigation
© Moein and Menon; licensee BioMed Central Ltd. 2014
Received: 26 May 2014
Accepted: 3 September 2014
Published: 11 September 2014
Disorders associated with excessive swelling of the lower extremities are common. They can be associated with pain, varicose veins, reduced blood pressure when standing and may cause syncope or fainting. The common physical remedy to these disorders is the use of compression stockings and pneumatic compression leg massagers, which both attempt to limit blood pooling and capillary filtration in the lower limbs. However, compression stockings provide a constant pressure, and their efficiency has been challenged according to some recent studies. Air compression leg massagers on the other hand, restricts patient mobility. In this work we therefore present an innovative active compression bandage based on the use of a smart materials technology that could produce intermittent active pressure to mitigate the symptoms of lower extremity disorders.
An active compression bandage (ACB), actuated by shape memory alloy (SMA) wires, was designed and prototyped. The ACB was wrapped around a calf model to apply an initial pressure comparable to the one exerted by commercial compression stockings. The ACB was controlled to apply different values of compression. A data acquisition board and a LabVIEW program were used to acquire both the pressure data exerted by the ACB and the electrical current required to actuate the SMA wires. An analytical model of the ACB based on a SMA constitutive model was developed. An optimizer was implemented to identify optimal parameters of the model to best estimate the performance of the ACB.
The maximum increase in pressure due to the SMA wires activation was 40.8% higher than the initially applied pressure to the calf model. The analytical model of the ACB estimated the behaviour of the ACB with less than 0.32 mmHg difference with the experimental results.
The prototyped ACB was able to apply an initial compression comparable to the one applied by commercial compression stockings. Activation of the ACB resulted in an increase of compression up to 9.06 mmHg. Comparison between analytical and experimental results showed the analytical model was suitable to predict the behaviour of the ACB.
Gravitational forces affect venous return thus resulting in the accumulation of blood in the lower extremities when standing upright. Considering venous compliance and expansion of the veins with blood, most of the blood volume change occurs in the veins . This leads to an increase of venous volume and pressure in the feet and lower limbs. Venous pooling and enhanced capillary filtration in the upright position may cause most syncopal events to be triggered by orthostatic stress . Syncope, or fainting, is a transient loss of consciousness and postural tone that typically occurs when upright and is correlated with reduced cerebral blood flow [2, 3]. In order to prevent decrease of blood pressure and cerebral blood flow, the reduction of venous return should be compensated - applying an external compression to lower limbs could be effective  to assist venus return. One of the current remedies to prevent or delay syncope is the use of compression stockings. This is recommended for those suffering from recurrent orthostatic intolerance, according to the explanation that external counter-pressure of the lower extremities or abdomen can decrease venous pooling and capillary filtration, thereby increasing venous return [5, 6]. This compression could also help the calf muscle pump resulting in reduction of oedema, microcirculation improvement and skin breakdown prevention [7, 8]. Some other studies have also investigated the effectiveness of compression stockings [9–13]. However, their efficiency has been challenged in many studies [11, 12]. One of the limitations of using the compression stockings is the compliance that is necessary to optimize effectiveness . These studies have suggested an individualized tailored design when considering treatment with compression stockings. Furthermore, using of intermittent pneumatic compression has been discussed in the literature . Some researches substantiate the idea that intermittent calf compression could be more effective and should be considered for some group of patients [15, 16]. But its use showed some practical problems such as restriction of patient mobility. The above-mentioned issues of the currently available solutions provide evidence of the need for a novel technology. This technology should provide desired compliance for the patients, be able to apply different ranges of compression based on patients’ leg size and hemodynamic characteristics and alter its amount.
In this work, we proposed the use of shape memory alloys (SMAs) for the design of an ambulatory active compression bandage (ACB). This ACB, which is capable of actively applying an altering external pressure on the lower limbs, has been prototyped using smart alloys technology and its performance was investigated.
SMAs are a group of metallic alloys that exhibit the characteristics of either large recoverable strains or large force due to temperature and/or load changes. They have drawn strong interest in recent years in a large variety of applications including in biomedical engineering. A good summary of design feasibility and applications, as well as overview of SMAs, are presented in .
One of the shape memory effect characteristics in SMAs is recovery stress effect. This effect occurs when an elongated SMA sample is restrained while being heated, a significant stress can be produced to prevent the SMA sample from recovering to its original shape . Very few experimental tests or analyses of the behaviour of SMA wires under recovery stress were reported. A recent study has conducted a series of tests of NiTiNb martensitic SMA wires under recovery stress with varying degrees of pre-strain on the wires, and compared the behaviour under recovery stress with that under pre-stressing of the wires. The results showed that the remaining stress (initial applied stress) was reduced by the procedure of loading and unloading additional strain. The more additional strains resulted in the more reduction of remaining stresses . In this study, NiTi SMA wires were utilized in a condition considering recovery stress characteristic of SMAs. This condition makes applying initial constant pressure and then variable increase in pressure to the calf available.
In order to model the phase transformation and thermochemical behaviour of SMAs, extensive research has been conducted. Presented models were mostly one-dimensional. These models were divided into four categories by Brinson et al. and included phenomenological laws based on uniaxial stress–strain–temperature data . They were each aimed at describing a different aspect of shape memory behaviour and addressed the thermomechanical behaviour of SMAs based on the phase transformation process on different scales . For this paper, an analytical model was developed to model the behaviour of the ACB. In the model, a well established phenomenological model for describing the behaviour of the SMA wires under thermomechanical loads was used. So the performance of the presented constitutive model could be evaluated for use in further parametric analysis and design improvement of the ACB, utilizing recovery stress characteristics of the SMAs. Genetic algorithm (GA) was utilized to find the key parameters of the analytical model to cover the complete range of applied electrical current in the experiments.
The organization of this paper is as follows. In following section, design and fabrication of the ACB is presented. Then, modelling of the ACB including the constitutive model of SMA is discussed. Next, the experimental setup is described. Finally, the experimental and modelling results are reported and discussed in detail. These sections are followed by the conclusion of the study.
Design and fabrication of the ACB
In this study, the ACB was designed to create a compression range similar to the mildest grade of compression stockings. These stockings apply a pressure of 15−20 mmHg (2000−2670 Pa) from the knee to the ankle . To fabricate the ACB prototype, the number of the SMA wires was calculated as N=6 using equation (4) and assuming 20 mmHg of initial compression and the 300 MPa for the longitudinal stress of the wires. These values were chosen to generate pressure in the range of commercial stockings and get to the maximum potential of the SMA wires used in the ACB.
Modelling of the ACB
An analytical model using a constitutive model for the SMA was developed to evaluate the behaviour of the ACB. Inputs of the model are the physical and thermal properties of the SMA wires and the plastic sheet used in the ACB, initial pressure of the chamber, input electrical current, and ambient temperature. The output of the model is the CM pressure that was compared with the experimental data.
The final pressure of the chamber, P in , can be calculated using equation (4). As mentioned above, the number of the SMA wires, N, used in the experiments was 6 and the longitudinal stress of a single wire, σ, was calculated by the constitutive model.
Constitutive model of SMA
where ε L is the maximum recoverable strain and Θ T is the thermal expansion factor . The martensite fraction (ξ) characterizes the extent of the martensite phase transformation. It is a parameter given by 0≤ξ≤1. When ξ=1, it means that the SMA is completely in the martensite phase, and when ξ=0, the SMA wire is completely in the austenite phase .
where is mass per unit length of wire, ρ is density of wire, d=102 μ m is diameter of wire, is the circumferential area of the unit length of wire, the effective conduction area of the unit length of wire, L and K Lexan are the thickness and thermal conductivity of Lexan sheet respectively, and was used in the ACB, c p is the specific heat, I is tha electrical current, R is the resistance per unit length of wire, T is the temperature of the wire, T ∞ is the ambient temperature, and h c is the heat convection coefficient.
in which α=R/m c p and β=[h c A c +(L/(K Lexan A sheet )+1/(h c A sheet )]/mc p . Steady state temperature can be calculated using equation (9) and initial temperature.
where , and C A are curve-fitting parameters . A s and A f are the austenite start and final temperatures respectively. The phase transformation occurs above A s up to A f . Generally, if there is some stress, the austenite start and final temperatures will be increased . The new austenite start and final temperatures are defined as and respectively.
In the temperatures higher than , there is new austenite and the equation (11) will be the constitutive equation.
SMA wire’s mass per unit length
SMA wire’s circumferential area per unit length
Effective conduction area per unit length
Thermal conductivity of Lexan sheet
W m−1 °C−1
Specific heat of wire
J kg−1 °C−1
SMA wire’s resistance per unit length
Ω m −1
Heat convection coefficient
W m−2 °C−1
Austenite Young modulus
Martensite Young modulus
SMA wire’s thermal expansion factor
Maximum recoverable strain
Initial martensite fraction factor
Average initial stress
Austenite start temperature
Austenite final temperature
Austenite curve fitting parameter
The experimental setup included the calf model (CM) and one pressure transducer connected to the CM through tubing. The CM was designed in three chambers representing the ankle, mid-calf and knee sections of the calf. The chambers can be separated to study a specific region of the calf or can be connected together to study the calf as a whole segment . It was assumed that the human calf is conical and the diameters in the CM were designated based on the reported average size of human calf [33, 34]. Figure 1(b) shows middle section of the CM.
The CM consists of two columns of structure, representing the tibia and fibula bones. The chamber of the CM is covered by a flexible silicone elastomer. Any small variation of the external pressure by the bandage can be detected by using a pressure transducer connected to the enclosed volume of each chamber. A data acquisition board and a LabVIEW program were used to acquire and record the data from the pressure transducer during the experiments. This measured pressure is the summation of the pressure applied by the ACB and the skin pressure. So, prior to the bandage wrapping, the pressure due to the skin itself should be measured and subtracted from the total pressure in the tests results. The chambers were filled in with an incompressible fluid, deionized (DI) water, to limit volume change effects seen for a compressible medium, and the volume of each chamber was kept constant during the experiments. The applied voltage to the SMA wires and produced electrical current were also acquired using the aforementioned data acquisition board and the LabVIEW program simultaneously with the pressure.
The pressure exerted by the ACB consists of two components. First, the mechanical pressure, which is the intial pressure produced by having the ACB wrapped around the leg. This produces the initial stress in the SMA wires. Second, the actuation pressure that is the result of the heating up of the SMA wires by applying voltage. The total pressure exerted by the ACB on the calf is determined by adding the actuation pressure to the mechanical pressure.
Results and discussions
Measurements of the compression exerted by the fabricated ACB were recorded on the middle chamber of the CM. The middle chamber was filled in with DI water until the shape of it became conical. The value of the pressure applied by the skin was read prior to the wrapping of the bandage and subtracted from the total pressure.
Results presented in Figure 5 were used to model the system. The above-mentioned decrease in the initial longitudinal stress of the SMA wires was considered in the performed optimization to obtain an accurate model. Specifically, the initial stress, , was calculated using both equation (4) and the experimental measurement of the inner pressure, P in , for each actuation cycle.
In this paper an ambulatory active compression bandage using shape memory alloys (SMA) was presented as proof of concept to potentially prevent and eliminate orthostatic intolerance. Based on the obtained experimental results, the prototyped ACB showed a desirable capability of applying initial mechanical pressure similar to commercial compression stockings, and also active alternations in pressure by electrical stimulation. The ACB was able to generate a significant gradient of pressure. In fact, 9.06 mmHg was reached when an electrical current of 219.88 mA was applied.
The analytical model used in this study could predict changes in pressure generated by the ACB with less than a 0.32 mmHg difference with experimental results. The model could be used for improving the ACB design and performing future parametric studies.
Future research includes identifying, via a clinical study, the optimum ACB activation timing to treat disorders associated with excessive swelling of the lower extremities given the maximum variation of pressure that the ACB can achieve. Future research should also investigate reliability of the ACB when it undergoes a large number of cyclic loads.
This research was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canadian Institutes of Health Research (CIHR). The authors would like to thank Drs. Andrew Blaber and Victoria Claydon for providing guidance in cardiovascular physiology. The authors would also like to thank the members of the MENRVA research group specially Mr. Ausama Ahmed for his scientific advices in the modelling and Mr. Shahram Pourazadi and Ms. Mahan Rahimi for their help in the experiments.
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