Infrared thermography fails to visualize stimulation-induced meridian-like structures: comment by Rixin Chen and Zhimai Lv and reply from Gerhard Litscher
© Chen et al; licensee BioMed Central Ltd. 2011
Received: 10 July 2011
Accepted: 11 September 2011
Published: 11 September 2011
A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author.
Comment: Rixin Chen and Zhimai Lv
Acupuncture is an important part of traditional Chinese medicine, which contributed to the proliferation of the Chinese in the passed thousand years. However, the studies of its mechanisms began from 20th century. As the acupuncture point and the meridian being the important physiological basis of acupuncture treatment, a lot of scholars have investigated their anatomical and physiological basis. Despite all that, from the perspective of modern medicine, it could not give an accurate definition to the acupuncture point, let alone to understanding of the meridian.
We are glad to see the article, entitled "Infrared thermography fails to visualize stimulation-induced meridian-like structures", in your magazine of BioMedical Engineering OnLine . The author came to the conclusion with precision testing and the strict logical analysis. However, if the design of experimental method could consider the following three aspects, the meridian-like phenomenon might be visualized.
1. Choosing volunteers
The acupuncture point is not a single part of the body surface; it is a functional state of certain part of the living body. The functional state is closely related to the pathological process of diseases. When a patient's condition has improved, the functional state is weakening or normalized. The so called acupuncture points on the healthy adult's surface are only parts of the body surface, while the points on the patient's surface are known as real acupuncture points . The subjects selected were all healthy adults. Hence, the meridian-like structures could not be observed by stimulating on the non-specific functioning parts. On the contrary, it might be observed by choosing sick individuals as subjects.
2. Treatment Duration
The duration of suspended moxibustion treatment is considered to be the important facts on meridian-Qi excitation and its efficacy. The application of suspended moxibustion within 15 minutes is considered the stage of meridian-Qi excitation, while an extended period of suspended moxibustion may provide an effective treatment stage . The meridian-like structures could not be observed clearly in the period of meridian-Qi excitation. Since the duration chose was 5-10 minutes, it was difficult to visualize the meridian-like structures. If the duration could be extended to 40 minutes, it would be helpful to observe it.
3. Acupuncture sites
Paging through the pre-qin period of literature, the acupuncture point is not fixed on the certain point of the body surface but a general area. There is a sensitive point in this area. If giving a proper physical stimulation to the sensitive point, such as heat or force, the meridian-Qi can be excited and the disease can be remedied effectively . However, it was not pointed out that whether the points selected to be stimulated was the sensitive point. Therefore, it was hard to visualize the meridian-like structures.
At present, many experiments related acupuncture might have been neglected the three contents in the design of the study. Therefore, the results are very different so that the effects of acupuncture or moxibustion remain elusive . If we could pay an attention to the contents above, the results might be the other way.
Reply: Gerhard Litscher
Background of this contribution
Unfortunately the letter to the editor entitled "Infrared thermography fails to visualize stimulation-induced meridian-like structures: Comment" by Rixin Chen and Zhimai Lv contains neither data nor facts, however there are some well-known useful comments to the study design which was not performed by our group. In this context I would like to thank the editor-in-chief of Biomedical Engineering OnLine, Professor Foster, for the opportunity to summarize once again some important facts on the topic in this standard journal article, which also serves as reply.
Bioengineering assessment of acupuncture in Graz
Basic research on high-tech acupuncture has been successfully performed in Graz since 1997 using a broad spectrum of methods. Main goal of these activities was to combine basic research on the topic of high-tech acupuncture with necessary further experimental and clinical pilot studies in China for the first time.
Acupuncture has been used as medical treatment for thousands of years. A large number of empirical data is available, but the technical quantification of effects was not possible up to now. Using electroacupuncture, needle or laser needle stimulation and modern biomedical techniques, it was possible to quantify changes in biological activities caused by acupuncture [5–15].
Infrared thermography and meridian-like structures
Discussion and Conclusion
Firstly, I would like to point out that Chen and Lv seem to have misunderstood the goal of our original study . The main goal of this study was not to prove or disprove the existence of meridians, but to reproduce another study mentioned above  which claims to have found visualized proof of meridians using thermography.
"Goal of scientific methods is the demarcation of dogmas. Scientific research is based on three currently valid theories: "instrumental injection", i.e. concrete methodology, "direct perception" and "common confirmation or refutation". (see comment to ). We followed these guidelines exactly in our scientific publication  with regard to infrared analysis and meridians. With the help of modern, infrared thermographic measurement equipment, we were not able to visualize meridians (energetic paths in Traditional Chinese Medicine) using an already described and extended methodological concept." (see comment to )
Secondly, I would like to cite Professor John Longhurst exemplarily: "Sometimes thermograms have been thought to actually show the pathway of a weakly luminescent meridian, but such demonstrations have been inconsistent between meridians. Furthermore, there is no physical proof that such oscillations occur, that they change with disease or that they actually represent meridians. There simply is no evidence for the existence of meridians based on this theory." 
Thirdly, from my point of view, there is nothing that needs to be added to this statement at the moment.
Chen RX, professor, the founder of Heat-sensitive Moxibustion, Affiliated Hospital of Jiangxi University of TCM, Nanchang, China.
Lv ZM, the main participant in the basic research of Heat-sensitive Moxibustion, a neurologist of the First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Rixin Chen and Zhimai Lv would like to thank the Major State Basic Research Development Program of People's Republic of China (2009CB522902), the National Natural Science Foundation of China (30760320), Jiangxi Key R&D Project, Natural Science Foundation of Jiangxi Province (2010Gzy0126) and Traditional Chinese Medicine Research Fund of Health Department of Jiangxi Province (2009Z05) for their support.
Gerhard Litscher wants to thank all the members of the Asian-Austrian high-tech acupuncture network.
- Litscher G: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed Eng Online 2005, 4: 38. 10.1186/1475-925X-4-38View ArticleGoogle Scholar
- Chen RX, Chen MR, Kang MF: Practical Reading of Heat-sensitization Moxibustion. Beijing: People's Medical Publishing House; 2009.Google Scholar
- Chen RX, Lv ZM, Chen MR, An X, Xie DY, Yi J: Neuronal apoptosis and inflammatory reaction in rat models of focal cerebral ischemia following 40-minute suspended moxibustion. Neural Regen Res 2011, 6: 1180–1184.Google Scholar
- Lee MS, Kang JW, Ernst E: Does moxibustion work? An overview of systematic reviews. BMC Res Notes 2010, 3: 284. 10.1186/1756-0500-3-284View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 1. thermography. Crit Rev Biomed Eng 2006, 34(1):1–22.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 2: Monitoring of microcirculation. Crit Rev Biomed Eng 2006, 34(4):273–294.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 3: ultrasound. Crit Rev Biomed Eng 2006, 34(4):295–326.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 4: functional magnetic resonance imaging. Crit Rev Biomed Eng 2006, 34(4):327–345.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 5: Cerebral near infrared spectroscopy. Crit Rev Biomed Eng 2006, 34(6):439–457.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 6: Monitoring - neurophysiology. Crit Rev Biomed Eng 2007, 35(1):1–38.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 7: Heart rate variability. Crit Rev Biomed Eng 2007, 35(3–4):183–195.View ArticleGoogle Scholar
- Litscher G: Bioengineering assessment of acupuncture, part 8: Innovative moxibustion. Crit Rev Biomed Eng 2010, 38(2):117–126.View ArticleGoogle Scholar
- Litscher G: Ten years evidence-based high-tech acupuncture - A short review of peripherally measured effects. Evid Based Complement Alternat Med 2009, 6(2):153–158. 10.1093/ecam/nem145View ArticleGoogle Scholar
- Litscher G: Ten years evidence-based high-tech acupuncture - A short review of centrally measured effects (part II). Evid Based Complement Alternat Med 2009, 6(3):305–314. 10.1093/ecam/nem169View ArticleGoogle Scholar
- Litscher G: Ten years evidence-based high-tech acupuncture, part 3: A short review of animal experiments. Evid Based Complement Alternat Med 2010, 7(2):151–155. 10.1093/ecam/nen034View ArticleGoogle Scholar
- Litscher G: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed Eng Online 2005, 4: 38. [http://www.biomedical-engineering-online.com/content/4/1/38] 10.1186/1475-925X-4-38View ArticleGoogle Scholar
- Schlebusch KP, Maric-Oehler W, Popp FA: Biophotonics in the infrared spectral range reveal acupuncture meridian structure of the body. J Altern Complement Med 2005, 11(1):171–173. 10.1089/acm.2005.11.171View ArticleGoogle Scholar
- Litscher G, Ammer K: Visualization of equipment dependent measurement errors, but not of meridian-like channels in complementary medicine - a thermographic human cadaver study. Thermology international 2007, 17(1):32–35.Google Scholar
- Longhurst JC: Defining meridians: A modern basis of understanding. J Acupunct Meridian Stud 2010, 3(2):67–74. 10.1016/S2005-2901(10)60014-3View ArticleGoogle Scholar
- Litscher G: Wissenschaftliche Grundlagen der Akupunktur. In Das große Buch der klassischen Akupunktur. Edited by: Bahr F, Bushe-Centmayer K, Dorfer L, Jost F, Litscher G, Suwanda S, Zeitler H. Munich Jena: Elsevier Urban & Fischer; 2007:1–109. (German)View ArticleGoogle Scholar
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