Figure 10

MRSA infection of HUVEC under flow versus time. (A) Percentage of HUVEC infected and (B) average number of adherent or internalized MRSA per HUVEC for dynamic MRSA adhesion experiments versus time at 0.24 Pa. (C) The number of experimentally determined bacteria per area normalized against the dimensionless cell concentration versus shear rate. The error bars for SEM were smaller than the markers for each data point and were not included in the graph. Number of samples analyzed: for static conditions: 15 min: 3 experiments, 556 HUVEC, 2790 MRSA; 30 min: 3 experiments, 411 HUVEC, 4495 MRSA; 60 min: 3 experiments: 423 HUVEC, 4078 MRSA. For 293s^-1: 15 min - 3 experiments, 519 HUVEC, 3959 MRSA; 30 min- 4 experiments, 462 HUVEC, 3795 MRSA; 60 min- 3 experiments: 523 HUVEC, 14,932 MRSA; For 1460s^-1 at 30 min: 4 experiments, 546 HUVEC, 3000 MRSA. Error bars are plotted as standard error of the mean (SEM).