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Volume 16 Supplement 1

Selected articles from the 4th International Work-Conference on Bioinformatics and Biomedical Engineering-IWBBIO 2016


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Grenada, Spain20-22 April 2016

Conference website

Edited by Ignacio Rojas, Francisco Manuel Ortuño and Olga Valenzuela.

  1. Content type: Research

    The immunotoxicity of engine exhausts is of high concern to human health due to the increasing prevalence of immune-related diseases. However, the evaluation of immunotoxicity of engine exhausts is currently b...

    Authors: Chia-Chi Wang, Ying-Chi Lin, Yuan-Chung Lin, Syu-Ruei Jhang and Chun-Wei Tung

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):66

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  2. Content type: Research

    Gene expression analyses demand appropriate reference genes (RGs) for normalization, in order to obtain reliable assessments. Ideally, RG expression levels should remain constant in all cells, tissues or exper...

    Authors: Rosario Carmona, Macarena Arroyo, María José Jiménez-Quesada, Pedro Seoane, Adoración Zafra, Rafael Larrosa, Juan de Dios Alché and M. Gonzalo Claros

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):65

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  3. Content type: Research

    Nowadays, sleep quality is one of the most important measures of healthy life, especially considering the huge number of sleep-related disorders. Identifying sleep stages using polysomnographic (PSG) signals i...

    Authors: Shirin Najdi, Ali Abdollahi Gharbali and José Manuel Fonseca

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):78

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  4. Content type: Research

    A key challenge in the realm of human disease research is next generation sequencing (NGS) interpretation, whereby identified filtered variant-harboring genes are associated with a patient’s disease phenotypes...

    Authors: Noa Rappaport, Simon Fishilevich, Ron Nudel, Michal Twik, Frida Belinky, Inbar Plaschkes, Tsippi Iny Stein, Dana Cohen, Danit Oz-Levi, Marilyn Safran and Doron Lancet

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):72

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  5. Content type: Research

    Examination of physiological processes and the influences of the drugs on them can be efficiently supported by mathematical modeling. One of the biggest problems is related to the exact fitting of the paramete...

    Authors: Magdalena Ochab, Krzysztof Puszynski and Andrzej Swierniak

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):77

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  6. Content type: Research

    The present review collects the most relevant empirical evidence available in the literature until date regarding the effects of transcranial direct current stimulation (tDCS) on the human motor function. tDCS...

    Authors: Ana Sánchez-Kuhn, Cristian Pérez-Fernández, Rosa Cánovas, Pilar Flores and Fernando Sánchez-Santed

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):76

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  7. Content type: Research

    Many protein–protein interactions are mediated by a short linear motif. Usually, amino acid sequences of those motifs are known or can be predicted. It is much harder to experimentally characterize or predict ...

    Authors: Maciej Pawel Ciemny, Mateusz Kurcinski, Maciej Blaszczyk, Andrzej Kolinski and Sebastian Kmiecik

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):71

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  8. Content type: Research

    The characterization of protein–peptide interactions is a challenge for computational molecular docking. Protein–peptide docking tools face at least two major difficulties: (1) efficient sampling of large-scal...

    Authors: Mateusz Kurcinski, Maciej Blaszczyk, Maciej Pawel Ciemny, Andrzej Kolinski and Sebastian Kmiecik

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):73

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  9. Content type: Research

    This paper presents the preliminary results of a novel rehabilitation therapy for cervical and trunk control of children with cerebral palsy (CP) based on serious videogames and physical exercise.

    Authors: Miguel A. Velasco, Rafael Raya, Luca Muzzioli, Daniela Morelli, Abraham Otero, Marco Iosa, Febo Cincotti and Eduardo Rocon

    Citation: BioMedical Engineering OnLine 2017 16(Suppl 1):74

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