Table 5 LOC combined with other chips
From: Construction of in vitro liver-on-a-chip models and application progress
Picture | Cell type | Description | References |
|---|---|---|---|
| MSCs | Liver–kidney chip. To study the therapeutic effect and bio-distribution of MSC-EVs | [42] |
| PHHa | Liver–pancreas chip. Identify the characteristics of human metabolic response to pre-diabetes hyperglycemia | [43] |
| hiPSCs | Liver–brain chip. Consist of human blood–brain barrier, cortical brain, and liver models derived from fully autologous iPSC. Evaluate the permeability of drug blood–brain barrier | [44] |
| Calu-3b, HepG2/C3Ac | Liver–lung chip. Active and functional in vitro interference can be simulated in a stress-induced environment for inhalation toxicity assessment | [45] |
