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Table 1 Baseline characteristics of the study population

From: Prediction of non-perfusion volume ratio for uterine fibroids treated with ultrasound-guided high-intensity focused ultrasound based on MRI radiomics combined with clinical parameters

Characteristics

Training (n = 122)

P value

Internal validation (n = 46)

P value

External validation (n = 55)

P value

Group H (n = 60)

Group L (n = 62)

Group H (n = 22)

Group L (n = 24)

Group H (n = 30)

Group L (n = 25)

Age, years

41.0 ± 6.4

39.1 ± 6.5

0.121

39.6 ± 5.1

37.7 ± 6.1

0.793

39.1 ± 6.2

38.1 ± 8.6

0.196

Subcutaneous fat thickness (mm)

15.5 ± 5.5

17.1 ± 5.3

0.112

15.6 ± 5.1

16.2 ± 5.2

0.882

16.0 ± 3.7

17.2 ± 4.7

0.398

Thickness of the rectus abdominis (mm)

8.8 ± 2.4

8.1 ± 2.9

0.619

8.5 ± 3.6

8.1 ± 2.8

0.681

10.2 ± 2.7

10.6 ± 2.7

0.268

Diameter of UFs (cm)

5.3 ± 1.4

5.8 ± 1.4

0.062

5.7 ± 1.9

6.2 ± 2.2

0.361

5.3 ± 1.2

5.9 ± 1.5

0.152

Volume of UFs (cm3)

93.1 ± 75.7

117.7 ± 90.7

0.155

104.3 ± 117.8

139.1 ± 118.9

0.162

110.3 ± 82.2

132.6 ± 92.1

0.302

Distance (mm)a

92.4 ± 16.8

97.9 ± 15.6

0.062

91.1 ± 17.4

99.7 ± 13.8

0.069

93.1 ± 13.1

100.5 ± 11.7

0.095

Number of fibroids (total)

  

0.909

  

0.887

  

0.702

 1

45 (75.0%)

49 (79.1%)

 

16 (78.6%)

17 (72.4%)

 

21 (72.4%)

20 (76.9%)

 

 2–5

15 (25.0%)

13 (20.9%)

 

6 (21.4%)

7 (27.6%)

 

8 (27.6%)

6 21.1%)

 

SI on T2MRIb

  

0.000*

  

0.039*

  

0.016*

 Type 1

27 (45.0%)

17 (27.4%)

 

10 (45.5%)

6 (25.0%)

 

12 (40.0%)

7 (28.0%)

 

 Type 2

27 (45.0%)

20 (32.3%)

 

8 (36.4%)

4 (16.6%)

 

12 (40.0%)

3 (12.0%)

 

 Type 3

2 (3.3%)

19 (30.7%)

 

3 (13.6%)

7 (29.2%)

 

4 (13.3%)

11 (44.0%)

 

 Type 4

4 (6.7%)

6 (9.7%)

 

1 (4.5%)

7 (29.2%)

 

2 (6.7%)

4 (16.0%)

 

CDFI gradec

  

0.297

  

0.821

  

0.761

 Grade 1

21(35.0%)

16 (25.8%)

 

4 (18.2%)

5 (20.8%)

 

12 (40.0%)

9 (36.0%)

 

 Grade 2

39 (65.0%)

46 (74.2%)

 

18 (81.8%)

19 (79.2%)

 

18 (60.0%)

16 (64.0%)

 

Fibroid types

  

0.209

  

0.659

  

0.561

 Intramural

38 (63.3%)

48 (77.4%)

 

16 (72.7%)

20 (83.3%)

 

19 (63.4%)

13 (52.0%)

 

 Subserosal

8 (13.4%)

4 (6.5%)

 

2 (9.1%)

1 (4.2%)

 

4 (13.3%)

6 (24.0%)

 

 Submucosal

14 (23.3%)

10 (16.1%)

 

4 (18.2%)

3 (12.5%)

 

7 (23.3%)

6 (24.0%)

 
  1. Group H: NPVR ≥ 80%; Group L: NPVR < 80%
  2. UFs uterine fibroids
  3. *Significance indicated by P < 0.05
  4. aDistance: Distance from the back end of the fibroids to the skin surface
  5. bSI: signal intensity; Type 1: hypointense; Type 2: isointense; Type 3: homogeneous-type hyperintense; Type 4: heterogeneous-type hyperintense
  6. cCDFI: Color Doppler Flow Imaging; Grade 1: a small amount of blood flow in the fibroids, 1–2 punctate blood flows can be seen; Grade 2: moderate blood flow in fibroids, 1 main blood vessel can be seen, whose length exceeds the radius of the fibroids or 2–3 small blood vessels can be seen
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