Fig. 2

Voxel-wise lesion feature maps of features measured in subject space and summarized across female (F) and male (M) patients in template spaces. In each subplot, lung cancer (top panel), lymphoma (mid panel), and melanoma patients (bottom panel) are presented separately. In a and d, the feature shown is metabolic activity measured voxel-wise in subject space. In b and e, the feature shown is lesion volume mapped to each lesion in subject space. In c and f, the feature shown is total lesion count mapped to each lesion in subject space. In a–c, each pixel shows the mean feature value among lesions sampled at that location in space. High feature value is mapped to dark color. In d–f, each pixel shows the coefficient of variation (CV) among lesions sampled at that location in space. High variation is mapped to blue and low variation to yellow. Images are coronal maximum intensity projections. SUV standardized uptake value