Table 5 Classification of ADNI participants into CU, MCI and AD groups
| Â | CU | MCI | AD |
|---|---|---|---|
Subjective memory complaint | None | Yes | Yes |
MMSE score |  ≥ 24 |  ≥ 24 | Between 20 and 24 (Exceptions for 24 and 25 for participants with less than 8 years of education) |
CDR | CDR = 0 Memory Box score must be 0 | CDR = 0.5 Memory Box score of at least 0.5 | CDR = 0.5 or 1.0 |
Logical memory score |  ≥ 9 for 16 or more years of education  ≥ 5 for 8–15 years of education  ≥ 3 for 0–7 years of education |  ≤ 8 for 16 or more years of education  ≤ 4 for 8–15 years of education  ≤ 2 for 0–7 years of education |  ≤ 8 for 16 or more years of education  ≤ 4 for 8–15 years of education  ≤ 2 for 0–7 years of education |
General cognition and functional status | Cognitively normal based on the absence of significant impairment in cognitive functions or activities of daily living | General cognition and functional performance sufficiently preserved, such that a diagnosis of dementia cannot be made | NINCDS/ADRDA criteria for probable AD |