Fig. 3

In vitro anticancer effects. SW620 and CW-2 cell lines expressed the highest and lowest levels of EGFR (A and B). Under treatments with free CPT-11, liposomal CPT-11 (Lipo-CPT-11) or EGFR-Lipo-CPT-11 for 24 h, SW620 cells [highest EGFR-expressing cell lines] showed a significant reduction of cell viability while the CW-2 cell lines (lowest EGFR-expressing cell lines) were less affected (C and D)