Fig. 5

Regulation of wogonin on SIRT1-mediated HMGB1 deacetylation in LPS-induced A549 cells following treatment with wogonin. Western blot assay analyzed the expression of proteins involved in SIRT1-mediated HMGB1 deacetylation. All experiments were performed in triplicates (n = 3). ***P < 0.001 vs. control; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. LPS; ^&&&P < 0.001 vs. LPS + 5 μM wogonin; ^@P < 0.05, ^@@P < 0.01 vs. LPS + 10 μM wogonin