Fig. 5

Validation of candidate lncRNAs. A The expression of the downregulation candidate lncRNAs in 7 LUAD cell lines and BEAS-2B cells was determined by qRT-PCR. B The expression of upregulation candidate lncRNAs in 7 LUAD cell lines and BEAS-2B cells was determined by qRT-PCR. The data are presented as the mean ± standard error of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001. C The relative expression of the candidate DE lncRNA ENST00000609697 in the TCGA dataset. D Kaplan–Meier (KM) survival analysis based on the candidate DE lncRNA ENST00000609697. x axis: overall survival (years); y axis: survival rate. Green and red represent the low and high lncRNA expression groups, respectively