Moderate-intensity treadmill running relieves motion-induced post-traumatic osteoarthritis mice by up-regulating the expression of lncRNA H19

Table 2 Morphological changes of the subchondral bone of the medial and lateral tibial plateau in mice after moderate-intensity treadmill running

Group	BMD(mg HA/ccm)	BV/TV	Tb.N	Tb.Th	Tb.Sp
LRC	950.925 ± 27.040	0.5712 ± .033	7.166 ± 0.441	0.094 ± 0.008	0.131 ± 0.004
LM + R	999.071 ± 15.379*	0.5734 ± 0.037	7.370 ± 0.236	0.101 ± 0.010	0.128 ± 0.010
LM + C	987.680 ± 5.319*	0.629 ± .0117	6.951 ± 0.375	0.111 ± 0.005*	0.134 ± 0.011
MRC	969.248 ± 21.332	0.616 ± 0.056	7.094 ± 0.337	0.104 ± 0.017	0.139 ± 0.013
MM + R	1008.845 ± 4.041	0.647 ± 0.054	7.655 ± 0.318	0.119 ± 0.011	0.123 ± 0.011
MM + C	968.176 ± 4.204^##	0.572 ± 0.016	7.214 ± 0.268	0.092 ± 0.001	0.127 ± .006

Comparison of the BMD, BV / TV, Tb.N, Tb.Th and Tb.Sp of the subchondral bone under the medial and lateral tibial plateau in mice. (LRC group: RC group lateral tibia plateau, LM + R group: M + R group lateral tibia plateau, LM + C group: M + C group lateral tibia plateau, MRC group: RC group medial tibia plateau, MM + C group: M + C group medial tibia plateau, MM + R group: M + R group medial tibia plateau. n = 4, *P < 0.05, LM + R group or LM + C group VS LRC group, ^##P < 0.01, MM + C group VS MRC group)

ISSN: 1475-925X