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Table 4 The clinical metrics of ground-truth and predicted dose distribution using MSE loss and sharp loss (γ = 100)

From: Sharp loss: a new loss function for radiotherapy dose prediction based on fully convolutional networks

 

Ground truth

Predicted dose

MSE loss

Sharp loss (γ = 100)

PTV

 D95 (cGy)

5000.0 ± 0.0

4795.09 ± 173.60

4963 ± 96.30

 HI

0.12 ± 0.03

0.42 ± 0.04

0.19 ± 0.02

 CI

0.83 ± 0.04

0.56 ± 0.08

0.77 ± 0.63

Heart

 Mean (cGy)

625.42 ± 125.20

538.19 ± 147.21

644.46 ± 143.68

 V30 (%)

4.73 ± 1.94

3.0 ± 1.77

4.03 ± 1.77

Ipsilateral lung

 Mean (cGy)

1065.04 ± 46.28

978.22 ± 73.49

1094.99 ± 125.57

 V5 (%)

42.63 ± 2.73

44.8 ± 2.53

45.57 ± 4.13

 V20 (%)

19.21 ± 1.18

17.02 ± 1.99

18.82 ± 3.12

 V30 (%)

13.34 ± 1.28

9.76 ± 1.78

12.99 ± 2.60

Whole lung

 Mean (cGy)

597.11 ± 67.89

545.82 ± 52.60

623.70 ± 87.46

 V5 (%)

24.31 ± 5.90

23.22 ± 2.31

22.94 ± 3.45

 V20 (%)

9.02 ± 1.04

7.99 ± 1.12

8.87 ± 1.83

 V30 (%)

6.28 ± 0.86

4.61 ± 0.81

6.15 ± 1.48