Fig. 3
From: The significance of homeodomain transcription factor 2 in colon cancer cells
PITX2 bound the promoter region of lncRNA GHET1 and promoted the expression of lncRNA GHET1. A JASPAR analysis (http://jaspar.genereg.net/) predicted revealed that the expression of PITX2 was associated with that of lncRNA GHET1. B Luciferase reporter assay was performed to detect the relationship between PITX2 and lncRNA GHET1. C CHIP assay was performed to explore the binding between PITX2 and lncRNA GHET1. D The expression of lncRNA GHET1 in colon cancer cells was determined with the RT-PCR. E The expression of lncRNA GHET1 in SW480 cells was detected with the RT-PCR. ***p < 0.001 vs. HCoEpiC or control