Fig. 4
Neuronal responses induced by 200-Hz A-HFS in the hippocampal CA1 region. a and b Top: typical examples of recording signals in the S. pyr. with 1-min 200-Hz A-HFS (denoted by the red bar) of biphasic pulses (a) or monophasic pulses (b). Bottom: typical waveforms of APS induced by A-test pulses or A-HFS pulses in the periods before, during and after A-HFS. c Normalized APS amplitude in the first 5 s and last 2 s of 1-min A-HFS. d Comparison of the decrement of APS amplitude at 1 s (ΔA1s) between monophasic A-HFS (n = 5) and biphasic A-HFS (n = 4). e Comparison of the decrement of APS amplitude at 60 s (ΔA60s) between monophasic A-HFS (n = 5) and biphasic A-HFS (n = 4). *P < 0.05, t-test