Table 9 Area under the receiving operator curve (mean and 95% confidence interval) of the traditional FOT parameters in the identification of the bronchodilator response in patients with work-related asthma
| AUC | Se (%) | Sp (%) | Cut-off | |
|---|---|---|---|---|
| R0 |
0.699 0.570–0.829 |
74.1 55.4–88.1 |
58.0 39.1–75.5 | > 2.72 |
| Rm |
0.694 0.563–0.825 |
83.8 66.3–94.5 |
51.6 33.1–69.8 | > 2.39 |
| R4 |
0.708 0.580–0.835 |
93.5 78.6–99.2 |
38.7 21.8–57.8 | > 2.00 |
| R12 |
0.690 0.558–0.822 |
64.5 45.4–80.8 |
70.9 52.0–85.8 | > 2.46 |
| R20 |
0.691 0.558–0.824 |
74.1 55.4–88.1 |
61.2 42.2–78.2 | > 2.20 |
| S |
0.686 0.554–0.817 |
77.4 58.9–90.4 |
51.61 33.1–69.8 | ≤ − 19.9 |
| R4 − R20 |
0.677 0.542–0.813 |
61.2 42.2–78.2 |
70.9 52.0–85.8 | > 0.30 |
| Xm |
0.629 0.489–0.768 |
45.1 27.3–64.0 |
87.1 70.2–96.4 | ≤ − 0.35 |
| Fr |
0.634 0.494–0.773 |
51.6 33.1–69.8 |
77.4 58.9–90.4 | > 19.5 |
| Cdyn |
0.706 0.574–0.837 |
58.0 39.1–75.5 |
87.1 70.2–96.4 | ≤ 14.3 |
| Axt |
0.697 0.566–0.828 |
51.6 33.1–69.8 |
83.8 66.3–94.5 | > 18.6 |
| Axi |
0.665 0.530–0.800 |
61.29 42.2 – 78.2 |
64.52 45.4 – 80.8 | ≤ 9.10 |
| Z4 |
0.726 0.601–0.851 |
74.1 55.4–88.1 |
61.2 42.2–78.2 | > 3.36 |