Radiotherapy dose distribution prediction for breast cancer using deformable image registration

Table 3 Quantitative MAD results with standard deviation σ of three dose prediction methods

Method	PTV (cGy)	Ipsilateral lung (cGy)	Heart (cGy)	Lung (cGy)	Spinal cord (cGy)
SIM
Mean	235.6	250.7	202.8	152.9	61.4
σ	158.4	68.2	64.4	47.7	44.9
WEI_A
Mean	267.5	213.0	174.1	130.9	57.1
σ	176.4	50.8	55.7	26.2	39.9
WEI_F
Mean	227.4	197.9	166.0	122.3	55.3
σ	144.0	42.9	55.1	25.5	42.2
p	0.004*	0.002*	0.002*	0.002*	0.116
SIM–WEI_ A
p	0.627	0.015*	0.019*	0.073	–
SIM–WEI_F
p	0.232	0.002*	0.006*	0.012*	–
WEI_ A–WEI_F
p	0.000*	0.001*	0.001*	0.001*	–

Method	0.8 DSC	1.0 DSC	33 \(\gamma\)	55 \(\gamma\)
SIM
Mean	0.85	0.84	0.64	0.84
σ	0.05	0.05	0.13	0.10
WEI_A
Mean	0.86	0.82	0.55	0.75
σ	0.05	0.08	0.14	0.12
WEI_F
Mean	0.87	0.84	0.58	0.78
σ	0.05	0.07	0.15	0.13
p	0.015*	0.002*	0.000*	0.000*
SIM–WEI_A
p	0.135	0.156	0.002*	0.001*
SIM–WEI_F
p	0.017*	0.654	0.015*	0.015*
WEI_A–WEI_F
p	0.002*	0.000*	0.000*	0.000*

ISSN: 1475-925X