Fig. 10

Representative histopathology images of animals treated for BBB opening at various MB doses: 100 µL (a), 50 µL (b) and 5 µL (c). Microhemorrhage (arrows) and structural damage (arrowhead) are noted in higher magnification insets, located directly below each respective image. Scale bars in the whole brains and insets correspond to 2 mm and 200 μm, respectively