Fig. 1

Schematic illustration and in vitro sensitivity of the whole-body optical imaging system. a System setup. L lens, FW filter wheel. b Linearity and sensitivity within 1 s and c imaging depth of the optical system. mKate2 and Luc are indicated in red and blue, respectively. Microscopic results of MDA-MB-435s-mKate2 cells (d) and tumor tissue (f); and MDA-MB-231-GFP cells (e) and tumor tissue (g)