Fig. 1
From: Alzheimer’s disease diagnosis based on the Hippocampal Unified Multi-Atlas Network (HUMAN) algorithm
The HUMAN processing pipeline. A data driven template is built from controls, then training scans are warped and peri-hippocampal volumes of interest (VOI) are extracted. VOI is automatically traced on the template, such that hippocampi of warped scans are contained within. The most similar VOIs are used to select optimal atlases; finally, from each scan a neural network is trained to obtain a putative segmentation. The final segmentation is the average of putative segmentations, a Bayesian threshold is used to get a binary response