Quantification of confocal fluorescence microscopy for the detection of cervical intraepithelial neoplasia

Table 4 Sensitivity and specificity of ENC ratio and 3NDND for the detection of cervical dysplasia at different confocal imaging depths

Imaging depth	QTP features	Detecting high-grade lesions		Detecting any lesions
Imaging depth	QTP features	Sensitivity (%)	Specificity (%)	Sensitivity (%)	Specificity (%)
Surface	ENC ratio	85	92	100	83
Surface	3NDND	71	85	66	83
15 µm	ENC ratio	100	92	100	83
15 µm	3NDND	100	85	80	83
30 µm	ENC ratio	50	78	92	66
30 µm	3NDND	83	71	78	66

ISSN: 1475-925X