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Table 4 Sensitivity and specificity of ENC ratio and 3NDND for the detection of cervical dysplasia at different confocal imaging depths

From: Quantification of confocal fluorescence microscopy for the detection of cervical intraepithelial neoplasia

Imaging depth QTP features Detecting high-grade lesions Detecting any lesions
Sensitivity (%) Specificity (%) Sensitivity (%) Specificity (%)
Surface ENC ratio 85 92 100 83
3NDND 71 85 66 83
15 µm ENC ratio 100 92 100 83
3NDND 100 85 80 83
30 µm ENC ratio 50 78 92 66
3NDND 83 71 78 66