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Table 2 Spirometric, plethysmografic and diffusion characteristics of the studied subjects

From: Forced oscillations and respiratory system modeling in adults with cystic fibrosis

  Control group (n = 23) Cystic fibrosis (n = 27) p
Spirometry    
FVC (L) 4.2 ± 1.0 3.5 ± 1.3 0.03
FVC (%) 101.7 ± 13.0 84.1 ± 2 5.4 0.004
FEV1 (L) 3.7 ± 0.8 2.3 ± 1.1 0.0001
FEV1 (%) 105.2 ± 13.8 65.8 ± 28.6 0.0001
FEV1/FVC 88.7 ± 4.4 64.4 ± 13.9 0.0001
FEF25–75% (L) 4.6 ± 1.3 1.6 ± 1.3 0.0001
FEF25–75% (%) 113.3 ± 26.7 39.1 ± 30.0 0.0001
FEF25–75%/FVC 110.7 ± 23.8 41.8 ± 26.6 0.0001
Plethysmography    
TLC (L) 5.6 ± 1.0 5.7 ± 1.4 ns
TLC (%) 99.4 ± 12.2 100.2 ± 19.2 ns
FRC (L) 2.7 ± 0.6 3.4 ± 1.3 ns
FRC (%) 88.3 ± 17.4 100.6 ± 31.2 ns
RV (L) 1.6 ± 0.5 2.3 ± 1.4 0.008
RV (%) 101.5 ± 33.0 149.0 ± 95.2 0.007
RV/TLC 27.8 ± 8.7 39.2 ± 15.9 0.004
RV/TLC (%) 100.8 ± 28.6 144.4 ± 59.9 0.001
FRC/TLC 49.9 ± 8.0 56.3 ± 11.1 ns
Raw (cmH2O/L/s) 0.73 ± 0.28 1.94 ± 1.31 0.0001
SGaw (cmH2O−1 s−1) 0.49 ± 0.24 0.19 ± 0.12 0.0001