Chemical bonding of the bone bonding agent to the bone. With the infiltration of the applied amphiphilic bone bonding agent (yellow marked area) into the bone surface (grey marked area at the bottom of the diagram) a hybrid layer will be built. Therefore the hydrophilic monomers in the bone bonding agent serve to optimize the wetting of bone, which likewise has a hydrophilic character. Than, the functional groups of the bone bonding agent will build chemical bondings of electrostatic nature to bone. Thereby the hydrophilic carboxy groups (R-COOH) of the bone bonding agent are able to build a chemical connection to the calciumions (Ca2+) of the anorganic matrix of bone, while the hydrophilic hydroxy groups (R-OH) build a water-insoluble bond with the aminogroups (NH2) of the organic matrix of bone.