A finite element model for protein transport in vivo

Table 1 The results of parameter estimation for GFP-GR using an experimental time series obtained by the Fluorescence Recovery after Photobleaching (FRAP) technique.

run	D _f(μ m² s^-1)	$K_{a}^{*}$ (s^-1)	K^d(s^-1)	F _eq	C _eq	t _b(ms)	t _d(ms)	RMSE	R ²
1*	9.20	500	86.4	0.1473	0.8527	11.60	2	0.0255	0.9886
2	1.9049	1.0549	3.7657	0.7812	0.2188	265	0.948	0.0259	0.9897
3	1.2319	0.1113	12.0951	0.9909	0.0091	83	8985	0.0245	0.9903
4	3.4980	10.2501	8.3917	0.4502	0.5498	119	97.6	0.0275	0.9882
5	22.8472	369.7719	24.1606	0.0613	0.9387	41	2.7	0.0251	0.9898
6	81.9332	4785	75.4057	0.0155	0.9845	13	0.2	0.0233	0.9912
7	1.2160	0.7076	5057	0.9999	0.0001	0.2	1413	0.0245	0.9903
8	1.8034	0.5172	2.4778	0.8273	0.1727	403	1933	0.0259	0.9896
9	4.6451	35.3378	15.8084	0.3091	0.6909	63	28.3	0.0257	0.9895
10	4.4471	1.4531	2.0004	0.5792	0.4208	500	688	0.0321	0.9855
11	1.2014	0.00003	20.3473	1.0000	0.0000	49	3.3 × 10⁷	0.0246	0.9901
12	20.3662	928	62	0.0626	0.9374	16	1078	0.0233	0.9912
13	7.4662	101	23.3243	0.1876	0.8124	43	9901	0.0247	0.9904
14	1.2210	7.5124	1423	0.9947	0.0053	0.7	1333113	0.0245	0.9903
15	19.5330	160	13.9388	0.0801	0.9199	72	6250	0.0290	0.9865
16	1.2350	32.2818	1590	0.9801	0.0199	0.6	30977	0.0245	0.9902
17	11.0675	300.4231	40.4005	0.1185	0.8815	25	3329	0.0235	0.9910
18	9.1683	1524	237.1330	0.1346	0.8654	4	656	0.0239	0.9908
19	8.3273	145.5289	28.1600	0.1621	0.8379	35	6871	0.0241	0.9906
20	1.2275	23.0060	3478	0.9934	0.0066	0.3	43467	00245	0.9908
21	4.9839	653.6816	214.1402	0.2468	0.7532	5	1530	0.0239	0.9908
22	94.2711	1857.1133	27.6413	0.0147	0.9853	36	538.5	00247	0.9901
23	1.2584	21.1318	590	0.9654	0.0346	2	47322	0.0245	0.9903
24	4.5057	63.7910	26.8675	0.2964	0.7036	37	15676	0.0239	0.9908

* The parameter values in the first row were obtained by Sprague et al. (2004). The experimental FRAP data are from J. McNally (personal communication).

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