Sample time series plots of LVP and [Ca2+] from Control (A), Dobutamine (B), Dopamine (C), Digoxin (D), and Levosimendan (E) before (left panel) and after (right panel) ischemia . Diastolic Ca2+ detection points are shown for control. Extracellular CaCl2 was half-normal (1.2 mM) to allow for a full range of responses to the drugs. This accounts for the lower control values of systolic LVP and [Ca2+]. Phasic LVP was lower after ischemia in all groups but phasic [Ca2+] was higher only in the control group (see table 1).