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Table 1 Plantar, Auditory, Nerve Conduction and Reaction Time Metrics. Average reaction times to a plantar touch, a pure tone auditory stimulus, and rightward lateral movement of 4 mm at 100 mm/s2 in diabetic (Peripheral Neuropathy), non-diabetic (Neurologically Intact), and young adults. Metrics given in either average ± standard deviation format or median [25% quartile, 75% quartile] format. All metrics for Semmes-Weinstein Monofilament Threshold, Air Conduction Threshold, and Nerve Conduction Studies have been averaged over both the right and left sides of the body. NCV = Nerve Conduction Velocity

From: A comparative study of reaction times between type II diabetics and non-diabetics

Group

Peripheral Neuropathy (n = 13)

Neurologically Intact (n = 24)

Young Adults (n = 9)

Age (yrs)

60.6 ± 6.5

59.4 ± 8.0

22.7 ± 1.2

Tactile Semmes-Weinstein Monofilament Thresholds (N)

   

Base Metatarsal

3.610 [2.473, 4.000]

3.610 [2.440, 3.610]

0.07 [0.0200, 0.160] †

Big Toe

3.220 [2.220, 4.080]

3.610 [2.440, 3.840]

0.07 [0.0200, 0.160] †

Air Conduction Thresholds (dB)

   

1 K Hz

20.0 [15.0, 22.5]

15.0 [10.0, 20.0] †

 

2 K Hz

20.0 [15.0, 30.0]

15.0 [10.0, 22.5] ‡‡

 

4 K Hz

30.0 [17.5, 55.0]

25.0 [20.0, 35.0] ‡

 

8 K Hz

35.0 [22.5, 67.5] ‡

35.0 [20.0, 57.5] ‡

 

Peak Accel Thresholds (mm/s 2 ) to Platform Lateral Moves

   

1 mm

122.775 ± 68.964‡

108.417 ± 59.050 ‡

60.778 ± 51.832‡†

2 mm

77.407 ± 55.982 ‡†

42.664 ± 37.754 ‡†

10.386 ± 3.091†

4 mm

37.275 ± 30.341

18.572 ± 19.143

13.458 ± 8.343

8 mm

20.297 ± 18.680

14.077 ± 8.122

14.766 ± 8.012

16 mm

18.613 ± 9.790

11.258 ± 7.723

13.590 ± 9.083

Nerve conduction studies

   

Sensory NCV (m/s) – Sural

41.0 [37.0, 45.0] †

45.0 [42.0, 47.0] †

 

Motor NCV(m/s) Peroneal

42.0 [39.0, 46.0] †

48.0 [46.0, 49.0] †

 

Motor NCV(m/s) – Tibial

40.5 [36.0, 45.0] †

45.0 [42.25, 48.75] †

 

M-wave Latency (ms) – Peroneal

4.7 [4.15, 5.45]

4.6 [4.075, 5.3]

 

M-wave Latency (ms) – Tibial

5.35 [4.4, 7.0] *

4.8 [4.2, 5.6] *

 

F-wave Latency (ms) – Peroneal

52.7 [47.625, 60.950] †

49.7 [46.6, 52.325] †

 

F-wave Latency (ms) – Tibial

58.5 [52.6, 64.7] †

52.5 [50.450, 55.275]†

 

Reaction Times (ms)

   

Touch (Big Toe)

353.1 ± 113.6

331.5 ± 140.5

216.0 ± 64.3

Tone (1 kHz)

282.6 ± 65.2

276.9 ± 105.5

218.6 ± 64.3

4 mm Lateral Platform Movement @ 100 mm/s2

777.8 ± 243.0‡†

623.9 ± 191.4‡†

431.5 ± 59.1‡†

  1. †Indicates significant group difference
  2. ‡Indicates significant threshold difference
  3. *Indicates a trend to significant threshold difference (0.05 < p < 0.07)