Figure 5

Results of cross-sectional group comparison. Clusters of significant FA differences between HD subjects and controls for the three visits. Hot colors indicate FA reductions in the comparison controls vs. HD subjects, cold colors indicate FA increases in this comparison. (A) Representative slices of identical MNI coordinates (0/-29/0) for visits 1 to 3 with and without quality control (QC), respectively. Red circles indicate additional clusters depending if QC based gradient direction elimination was performed, or not. (B) Examples of clusters that are only present in one visit, depending if QC based gradient direction elimination was performed or not. An example is shown for each visit 1 to 3; for clarity of presentation, the respective slices of the other visits for which no clusters could be detected are not displayed.