|Analysis of the systemic arterial flow characteristics||Only the arterial network is modelled||
Characteristics of the three- and four-element Windkessel models [13, 15, 16, 43, 114, 167, 169, 170];|
Advantages and disadvantages of using the three element RCR model as aortic input impedance ;
Comparison of different configurations of three element and four element models as the embryonic aortic impedance ;
Investigation of aortic input impedance in infants and children by curve fitting to two, three and four element Windkessel models ;
Study of the linear and nonlinear formulations of the three element Windkessel model by considering the pressure-dependent capacitance effect in the arterial network [89, 90, 92];
Two port analysis to extend the Windkessel models by considering the venous side flow pulsations in the systemic loop [19, 20];
Ventricular-systemic arterial coupling .
|Hemodynamic response in the native cardiovascular system under various healthy and diseased conditions||Complete description of the native cardiovascular system||
Cardiovascular response in normal healthy subjects ;|
Study of the ventricular interaction effect .
Modelling the dysfunction in regional stunned myocardium of the left ventricular ;
Modelling of cardiac muscles in the study of mechanics and energetics of fibrillating ventricle ;
Study of changes in pulmonary venous pressure after the onset of left ventricular dysfunction .
|Hemodynamic changes under various surgical and therapeutical interventions.||The native cardiovascular system was partly changed.||
Circulation dynamics in the presence of the bidirectional cavopulmonary anastomosis in children with a uni-ventricular heart ;|
Rest and exercise hemodynamics in patients with total cavopulmonary connection ;
Modelling the hemodynamic characteristics in patients with hypoplastic left heart syndrome after the palliative Norwood operation ;
Study of the cardiovascular response in patients with right ventricular bypass and uni-ventricular circulation support ;
Modelled the cardiovascular control adaptations in chronic renal failure patients ;
Modelling of the hemodynamic response to hemodialysis induced hypovolemia .
Modelling of the cardio-pulmonary response under step-leap respiration exercise for the treatment of patients with Cor Pulmonale .
|Ventricular assist device support for heart failure||The native cardiovascular system was in heart failure condition, and a VAD model is coupled.||
Studies of cardiovascular response in the heart failure condition supported with various types of VADs [70, 85, 99, 174–178];|
Studies of cardiovascular response in the heart failure condition supported with intra-aortic balloon pumps ;
Comparison of the assistance action of different types of VAD and VAD motion profiles ;
Study of the effect of the inlet and outlet cannulation sites for connecting the VADs to the native cardiovascular system ;
Study of the physiological control of pulsatility gradient in rotary blood pump [33, 181].
|Study of cardiovascular response under neuro-regulation||The native cardiovascular system was coupled with the models for the nervous system||
Simulate the cardiovascular responses under neuro-regulation in various conditions of isocapnic hypoxia [41, 76], hemorrhage , hypercapnia and hypocapnic hypoxia , carotid occlusion ;|
Simulation of cardiopulmonary response in Valsalva manoeuvre ;
Simulation of circulation system response to acceleration stress ;
Simulation of the cardiovascular response to orthostatic stress .
|Study of special and local circulation loops in the cardiovascular system.||Only the local circulation loop was modelled, and arterial pressure or flow-rate was applied as upstream boundary condition.||
Simulation of human foetal cardiovascular system ;|
Studies of cerebral auto-regulation effect [100, 103], cerebral vasospasm , acute brain damage , and cerebral hemodynamics during arterial and CO2 pressure change ;
Modelling of coronary local circulation loop ;
Study of dependence of intra-myocardial pressure and coronary flow on ventricular loading and contractility [52, 93];
Study of venous valves in pressure shielding in the lower extremity ;
Simulation of venous circulation in lower extremities .
|As boundary condition in multi-scale simulation of cardiovascular dynamics||The 0D circulation system model was coupled with the distributed parameter models (1D, 2D or 3D).||Multi-scale simulation of the cardiovascular dynamics [147, 151, 153, 159, 160].|