Fig. 4

Experimental Setup: The BR was measured clinically in 12 HC and 11 iPD patients and analyzed with a high-framerate consumer camera. a The participants were filmed at a 45° angle, while the examiner performed the GTR. A blue/blue-toned glove was worn for better discrimination in the video analysis; b For the HC one video of the GTR was taken. iPD patients were examined before and 30 min after the intake of their standard L-Dopa medication. c, d In the next step, the MediaPipe face mesh algorithm was used for facial landmark detection. Based on the facial landmarks we defined two ROIs (Glabellar Region and Eye Region), from which information was extracted throughout the experiment, with which we were able to detect the occurrence of blinks and taps