Fig. 2
From: Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study
Simulated current–voltage (I–V) relationships. a–c Currents traces for WT, WT-D172N and D172N I K1 elicited by 400 ms depolarizing voltage steps from −120 to +20 mV and from a holding potential of −60 mV. d–f Current–voltage relationships. The current amplitude of the WT-D172N and D172N mutant conditions is significantly larger than that of the WT condition