Cut-off* | Sen (%) | Spe (%) | Youden | PPV (%) | NPV (%) |
---|
1.27 | 50.0 | 94.3 | 0.443 | 92.6 | 57.4 |
0.82 | 62.6 | 84.7 | 0.473 | 85.2 | 61.8 |
0.30#
| 72.4 | 76.6 | **0.490 | 81.3 | 66.4 |
-0.30 | 85.6 | 57.3 | 0.429 | 73.8 | 74.0 |
-0.72 | 92.0 | 44.3 | 0.363 | 69.9 | 79.7 |
- *Cut-off: cut-off values, derived from ln(odds), which is the natural logarithm of the odds (OD) from the age-adjusted multivariate regression model. A lesion with a ln(OD) value higher than or equal to a given cut-off point is regarded as IR test-positive.
- Sen: sensitivity; Spe: specificity; Youden: Youden's Index = sensitivity+specificity-1.
- PPV: positive predictive value; NPV: negative predictive value.
- ** highest Youden's Index value (#the most optimal cut-off point we selected from the model).
- The cut-off value was -3.51 when the sensitivity was 100% and the specificity 0%; it was 5.47 when the sensitivity was 0.57% and specificity 100% (not shown in the table because they didn't meet the selection criteria of cut-off points in our study).