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  1. Content type: Research

    Keratinocyte (KC) migration in re-epithelization is crucial in repairing injured skin. But the mechanisms of how mechanical stimuli regulate the migration of keratinocytes have been poorly understood.

    Authors: Dongyuan Lü, Zhan Li, Yuxin Gao, Chunhua Luo, Fan Zhang, Lu Zheng, Jiawen Wang, Shujin Sun and Mian Long

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):130

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    This article is part of a Supplement: Volume 15 Supplement 2

  2. Content type: Research

    Blood continuously flows through the blood vessels in the human body. When blood flows through the smallest blood vessels, red blood cells (RBCs) in the blood exhibit various types of motion and deformed shape...

    Authors: Hasitha-Nayanajith Polwaththe-Gallage, Suvash C. Saha, Emilie Sauret, Robert Flower, Wijitha Senadeera and YuanTong Gu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):161

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    This article is part of a Supplement: Volume 15 Supplement 2

  3. Content type: Research

    This study specifically focused on anatomical MRI characterization of the low shear stress-induced atherosclerotic plaque in mice. We used machine learning algorithms to analyze multiple correlation factors of...

    Authors: Bing Li, Yun Jiao, Cong Fu, Bo Xie, Genshan Ma, Gaojun Teng and Yuyu Yao

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):146

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    This article is part of a Supplement: Volume 15 Supplement 2

  4. Content type: Research

    Interaction between immunoglobulin-like receptor glycoprotein VI (GPVI) and collagen plays a central role in platelet activation and sequent firm adhesion. Of various antithrombotic agents targeting GPVI, anti...

    Authors: Wenping Liu, Guangjian Liu, Huiyun Zhou, Xiang Fang, Ying Fang and Jianhua Wu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):152

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    This article is part of a Supplement: Volume 15 Supplement 2

  5. Content type: Research

    In stent design optimization, the functional relationship between design parameters and design goals is nonlinear, complex, and implicit and the multi-objective design of stents involves a number of potentiall...

    Authors: Hongxia Li, Junfeng Gu, Minjie Wang, Danyang Zhao, Zheng Li, Aike Qiao and Bao Zhu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):148

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    This article is part of a Supplement: Volume 15 Supplement 2

  6. Content type: Research

    Implantation of a rotary blood pump (RBP) can cause non-physiological flow fields in the left ventricle (LV) which may trigger thrombosis. Different inflow cannula geometry can affect LV flow fields. The aim o...

    Authors: Sam Liao, Benjamin Simpson, Michael Neidlin, Tim A. S. Kaufmann, Zhiyong Li, Maria A. Woodruff and Shaun D. Gregory

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):136

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    This article is part of a Supplement: Volume 15 Supplement 2

  7. Content type: Research

    Mental arithmetic has been verified inducing cerebral and cardiovascular responses. However, the mechanism and sequential responses are still ambiguous. This study aims to reveal the mechanism of cardiovascula...

    Authors: Xiaoni Wang, Binbin Liu, Lin Xie, Xiaolin Yu, Mengjun Li and Jianbao Zhang

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):160

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    This article is part of a Supplement: Volume 15 Supplement 2

  8. Content type: Research

    Patients with multiple intracranial aneurysms present a great challenge to the neurosurgeon, particularly when presenting with subarachnoid hemorrhage. Misjudgment may result in disastrous postoperative reblee...

    Authors: Lijian Xu, Lixu Gu and Hao Liu

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):166

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  9. Content type: Research

    In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand ho...

    Authors: Yan-Xia Wang, Cheng Xiang, Bo Liu, Yong Zhu, Yong Luan, Shu-Tian Liu and Kai-Rong Qin

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 2):154

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  10. Content type: Research

    The last decades, rehabilitation has become a challenging context for mechatronical engineering. From the state-of-the-art it is seen that the field of prosthetics offers very promising perspectives to robotic...

    Authors: Pierre Cherelle, Victor Grosu, Manuel Cestari, Bram Vanderborght and Dirk Lefeber

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):145

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    This article is part of a Supplement: Volume 15 Supplement 3

  11. Content type: Review

    This paper presents a review on design issues and solutions found in active lower limb prostheses. This review is based on a systematic literature search with a methodical search strategy. The search was carri...

    Authors: Michael Windrich, Martin Grimmer, Oliver Christ, Stephan Rinderknecht and Philipp Beckerle

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):140

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  12. Content type: Review

    Virtual reality (VR) based applications play an increasing role in motor rehabilitation. They provide an interactive and individualized environment in addition to increased motivation during motor tasks as wel...

    Authors: Luara Ferreira dos Santos, Oliver Christ, Kedar Mate, Henning Schmidt, Jörg Krüger and Christian Dohle

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):144

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  13. Content type: Research

    Current prosthetic ankle joints are designed either for walking or for running. In order to mimic the capabilities of an able-bodied, a powered prosthetic ankle for walking and running was designed. A powered ...

    Authors: Martin Grimmer, Matthew Holgate, Robert Holgate, Alexander Boehler, Jeffrey Ward, Kevin Hollander, Thomas Sugar and André Seyfarth

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):141

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  14. Content type: Research

    In product development for lower limb prosthetic devices, a set of special criteria needs to be met. Prosthetic devices have a direct impact on the rehabilitation process after an amputation with both perceive...

    Authors: Tim Schürmann, Philipp Beckerle, Julia Preller, Joachim Vogt and Oliver Christ

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):143

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  15. Content type: Research

    In transfemoral (TF) amputees, the forward propulsion of the prosthetic leg in swing has to be mainly carried out by hip muscles. With hip strength being the strongest predictor to ambulation ability, an activ...

    Authors: Veerle Creylman, Ingrid Knippels, Paul Janssen, Evelyne Biesbrouck, Knut Lechler and Louis Peeraer

    Citation: BioMedical Engineering OnLine 2016 15(Suppl 3):142

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 3

  16. Content type: Research

    In schizophrenia, executive dysfunction is the most critical cognitive impairment, and is associated with abnormal neural activities, especially in the frontal lobes. Complexity estimation using electroencepha...

    Authors: Yi Yu, Yun Zhao, Yajing Si, Qiongqiong Ren, Wu Ren, Changqin Jing and Hongxing Zhang

    Citation: BioMedical Engineering OnLine 2016 15:131

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  17. Content type: Research

    The Eigenspace-based beamformers, by orthogonal projection of signal subspace, can remove a large part of the noise, and provide better imaging contrast upon the minimum variance beamformer. However, wrong est...

    Authors: Saeid Aliabadi, Yuanyuan Wang, Jinhua Yu, Jinxin Zhao, Wei Guo and Shun Zhang

    Citation: BioMedical Engineering OnLine 2016 15:127

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  18. Content type: Research

    Accurate synchronization between magnetic resonance imaging data acquisition and a subject’s cardiac activity (“triggering”) is essential for reducing image artifacts but conventional, contact-based methods fo...

    Authors: Nicolai Spicher, Markus Kukuk, Stefan Maderwald and Mark E. Ladd

    Citation: BioMedical Engineering OnLine 2016 15:126

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  19. Content type: Research

    The use of speech based data in the classification of Parkinson disease (PD) has been shown to provide an effect, non-invasive mode of classification in recent years. Thus, there has been an increased interest...

    Authors: He-Hua Zhang, Liuyang Yang, Yuchuan Liu, Pin Wang, Jun Yin, Yongming Li, Mingguo Qiu, Xueru Zhu and Fang Yan

    Citation: BioMedical Engineering OnLine 2016 15:122

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  20. Content type: Research

    Efficacy and high availability of surgery techniques for refractive defect correction increase the number of patients who undergo to this type of surgery. Regardless of that, with increasing age, more and more...

    Authors: Robert Koprowski, Michele Lanza and Carlo Irregolare

    Citation: BioMedical Engineering OnLine 2016 15:121

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  21. Content type: Research

    Accurate segmentation of blood vessels plays an important role in the computer-aided diagnosis and interventional treatment of vascular diseases. The statistical method is an important component of effective v...

    Authors: Pei Lu, Jun Xia, Zhicheng Li, Jing Xiong, Jian Yang, Shoujun Zhou, Lei Wang, Mingyang Chen and Cheng Wang

    Citation: BioMedical Engineering OnLine 2016 15:120

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  22. Content type: Research

    The existing techniques for simultaneous encryption and compression of images refer lossy compression. Their reconstruction performances did not meet the accuracy of medical images because most of them have no...

    Authors: Qingzhu Wang, Xiaoming Chen, Mengying Wei and Zhuang Miao

    Citation: BioMedical Engineering OnLine 2016 15:118

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  23. Content type: Research

    Metal artifacts appearing as streaks and shadows often compromise readability of computed tomography (CT) images. Particularly in a dental CT in which high resolution imaging is crucial for precise preparation...

    Authors: Mohamed A. A. Hegazy, Min Hyoung Cho and Soo Yeol Lee

    Citation: BioMedical Engineering OnLine 2016 15:119

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  24. Content type: Research

    Bipolar vessel sealing is an efficient electrosurgical procedure for the occlusion of blood vessels particularly during minimally invasive surgery. Reliable knowledge of the thermal spread is crucial for a saf...

    Authors: Jay Wagenpfeil, Christina Schöllig, Volker Mayer, Ronny Feuer, Bernhard Nold, Alexander Neugebauer, Michael Ederer, Ralf Rothmund, Bernhard Krämer, Sara Brucker, Markus Enderle, Oliver Sawodny and Julia Rex

    Citation: BioMedical Engineering OnLine 2016 15:117

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  25. Content type: Research

    Tumor hypoxia is involved in every stage of solid tumor development: formation, progression, metastasis, and apoptosis. Two types of hypoxia exist in tumors—chronic hypoxia and acute hypoxia. Recent studies in...

    Authors: Chung-Wein Lee and Keith M. Stantz

    Citation: BioMedical Engineering OnLine 2016 15:114

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  26. Content type: Research

    Since hemodynamics plays a key role in the development and evolution of cardiovascular pathologies, physician’s decision must be based on proper monitoring of relevant physiological flow quantities.

    Authors: Kamil J. Chodzyński, Simone Gremmo, Omer F. Eker, Jacques Lalmand, Adel Aminian, Daniel Ribeiro de Sousa, Karim Zouaoui Boudjeltia and Grégory Coussement

    Citation: BioMedical Engineering OnLine 2016 15:113

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  27. Content type: Research

    Thoracoabdominal asynchrony is often adopted to discriminate respiratory diseases in clinics. Conventionally, Lissajous figure analysis is the most frequently used estimation of the phase difference in thoraco...

    Authors: Ya-Chen Chen and Tzu-Chien Hsiao

    Citation: BioMedical Engineering OnLine 2016 15:112

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  28. Content type: Research

    High order modulation and demodulation technology can solve the frequency requirement between the wireless energy transmission and data communication. In order to achieve reliable wireless data communication b...

    Authors: Yuan Yang, Nannan Quan, Jingjing Bu, Xueping Li and Ningmei Yu

    Citation: BioMedical Engineering OnLine 2016 15:110

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  29. Content type: Research

    Amyloid β-protein (Aβ) plaque deposition is an important prevention and treatment target for Alzheimer’s disease (AD). As a noninvasive, nonradioactive and highly cost-effective clinical imaging method, magnet...

    Authors: Yongming Li, Xueru Zhu, Pin Wang, Jie Wang, Shujun Liu, Fan Li and Mingguo Qiu

    Citation: BioMedical Engineering OnLine 2016 15:108

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  30. Content type: Research

    The goal of this paper is to present a computational fluid dynamic (CFD) model with moving boundaries to study the intraventricular flows in a patient-specific framework. Starting from the segmentation of real...

    Authors: A. M. Bavo, A. M. Pouch, J. Degroote, J. Vierendeels, J. H. Gorman, R. C. Gorman and P. Segers

    Citation: BioMedical Engineering OnLine 2016 15:107

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  31. Content type: Research

    The endothelial function has been proven to be an important factor in the pathogenesis of atherosclerosis, hypertension and heart failure. The flow-mediated vasodilation (FMD) of the peripheral artery is an en...

    Authors: Shing-Hong Liu, Jia-Jung Wang, Da-Chuan Cheng, Chun-Hung Su and Tzu-Hsin Lin

    Citation: BioMedical Engineering OnLine 2016 15:106

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  32. Content type: Research

    Microelectrode array (MEA) is a widely used technique to study for example the functional properties of neuronal networks derived from human embryonic stem cells (hESC-NN). With hESC-NN, we can investigate the...

    Authors: Kerstin Lenk, Barbara Priwitzer, Laura Ylä-Outinen, Lukas H. B. Tietz, Susanna Narkilahti and Jari A. K. Hyttinen

    Citation: BioMedical Engineering OnLine 2016 15:105

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  33. Content type: Research

    Inhaled nitric oxide (NO) is a selective pulmonary vasodilator used primarily in the critical care setting for patients concurrently supported by invasive or noninvasive positive pressure ventilation. NO deliv...

    Authors: Andrew R. Martin, Chris Jackson, Samuel Fromont, Chloe Pont, Ira M. Katz and Georges Caillobotte

    Citation: BioMedical Engineering OnLine 2016 15:103

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  34. Content type: Review

    Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range of cardiovascular system malfunctions that affect heart functionality. It is believed that the hemodynamic loads exerte...

    Authors: Siamak N. Doost, Dhanjoo Ghista, Boyang Su, Liang Zhong and Yosry S. Morsi

    Citation: BioMedical Engineering OnLine 2016 15:101

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  35. Content type: Research

    This study focuses on osteoarthritis (OA), which affects millions of adults and occurs in knee cartilage. Diagnosis of OA requires accurate segmentation of cartilage structures. Existing approaches to cartilag...

    Authors: Chunsoo Ahn, Toan Duc Bui, Yong-woo Lee, Jitae Shin and Hyunjin Park

    Citation: BioMedical Engineering OnLine 2016 15:99

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  36. Content type: Research

    Composition of atherosclerotic arterial walls is rich in lipids such as cholesterol, unlike normal arterial walls. In this study, we aimed to utilize this difference to diagnose atherosclerosis via multispectr...

    Authors: Cassandra Su Lyn Ho, Toshikatsu Horiuchi, Hiroaki Taniguchi, Araya Umetsu, Kohsuke Hagisawa, Keiichi Iwaya, Kanji Nakai, Amalina Azmi, Natasha Zulaziz, Azran Azhim, Nariyoshi Shinomiya and Yuji Morimoto

    Citation: BioMedical Engineering OnLine 2016 15:98

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  37. Content type: Review

    Teleoperated medical robotic systems allow procedures such as surgeries, treatments, and diagnoses to be conducted across short or long distances while utilizing wired and/or wireless communication networks. T...

    Authors: Sotiris Avgousti, Eftychios G. Christoforou, Andreas S. Panayides, Sotos Voskarides, Cyril Novales, Laurence Nouaille, Constantinos S. Pattichis and Pierre Vieyres

    Citation: BioMedical Engineering OnLine 2016 15:96

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  38. Content type: Research

    Out-of-hospital cardiac arrest is a life threatening situation where the first person performing cardiopulmonary resuscitation (CPR) most often is a bystander without medical training. Some existing smartphone...

    Authors: Kjersti Engan, Thomas Hinna, Tom Ryen, Tonje S. Birkenes and Helge Myklebust

    Citation: BioMedical Engineering OnLine 2016 15:95

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  39. Content type: Research

    Misalignment in cardiac magnetic resonance (CMR) images can adversely affect three-dimensional left ventricle modelling and downstream quantitative analysis. Currently, there are two types of approaches for de...

    Authors: Min Wan, Wei Huang, Jun-Mei Zhang, Xiaodan Zhao, John Carson Allen, Ru San Tan, Xiaofeng Wan and Liang Zhong

    Citation: BioMedical Engineering OnLine 2016 15:93

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