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Table 1 Comparing the performance of CBSS and HWM to estimate spikes based on simulated signals with varying parameters

From: Estimating the neural spike train from an unfused tetanic signal of low-threshold motor units using convolutive blind source separation

Simulation parameters

CBSS

HWM

Pairwise difference

p-value

FR (Hz)

ISI CV (%)

SNR (dB)

RoA (%)

RoA (%)

 

8

5

30

99.3 ± 0.8

100.0 ± 0.2

 − 0.7 ± 0.8

***

8

5

20

99.7 ± 0.5

99.9 ± 0.3

 − 0.2 ± 0.6

0.21

8

5

10

99.7 ± 0.6

99.5 ± 0.7

0.2 ± 1.0

1.00

8

20

30

99.1 ± 0.8

99.6 ± 0.7

 − 0.4 ± 1.1

*

8

20

20

99.5 ± 0.8

99.5 ± 0.7

0.0 ± 0.9

1.00

8

20

10

99.2 ± 0.9

98.0 ± 1.3

1.3 ± 1.4

***

8

40

30

97.5 ± 1.6

97.3 ± 2.0

0.3 ± 1.6

*

8

40

20

98.0 ± 1.4

96.8 ± 1.7

1.3 ± 1.8

***

8

40

10

97.2 ± 1.7

93.9 ± 2.5

3.2 ± 2.3

***

12

5

30

98.8 ± 0.5

98.7 ± 1.1

0.1 ± 1.3

0.38

12

5

20

98.8 ± 0.5

98.9 ± 1.0

 − 0.1 ± 1.0

1.00

12

5

10

98.0 ± 1.2

98.8 ± 1.0

 − 1.0 ± 1.4

***

12

20

30

98.8 ± 0.6

98.5 ± 1.2

0.4 ± 1.5

**

12

20

20

98.9 ± 0.7

98.4 ± 1.4

0.3 ± 1.1

***

12

20

10

97.6 ± 1.7

98.6 ± 1.2

 − 0.8 ± 1.5

*

12

40

30

97.3 ± 1.5

95.2 ± 2.4

2.4 ± 2.2

***

12

40

20

97.4 ± 1.6

95.3 ± 2.6

1.9 ± 2.4

***

12

40

10

95.2 ± 2.6

94.9 ± 2.0

0.4 ± 2.5

1.00

16

5

30

98.4 ± 1.1

98.4 ± 1.2

0.1 ± 1.6

1.00

16

5

20

98.3 ± 0.8

98.4 ± 1.2

 − 0.2 ± 1.4

1.00

16

5

10

94.8 ± 2.3

98.3 ± 1.3

 − 3.8 ± 1.8

***

16

20

30

98.5 ± 1.0

96.8 ± 1.4

2.0 ± 2.1

***

16

20

20

98.1 ± 1.5

96.7 ± 1.8

1.6 ± 1.7

***

16

20

10

93.6 ± 2.3

96.4 ± 1.7

 − 3.3 ± 2.4

***

16

40

30

96.0 ± 2.2

90.4 ± 2.8

5.6 ± 3.6

***

16

40

20

95.6 ± 2.0

90.4 ± 2.6

5.1 ± 3.5

***

16

40

10

89.6 ± 4.3

90.6 ± 3.2

 − 0.6 ± 3.5

1.00

Mean ± SD (across all parameter combinations)

97.5 ± 2.7

96.9 ± 3.3

0.6 ± 2.8

***

  1. FR firing rate, ISI inter-spike interval, CV coefficient of variation, SNR signal-to-noise ratio, CBSS = convolutive blind source separation, HWM Haar wavelet method, RoA rate of agreement. *p < 0.05, **p < 0.01, ***p < 0.001 using Bonferroni correction for multiple comparisons