Fig. 3

a Mean \(\Delta {C}_{{HbO}_{2}}\), b mean \(\Delta {C}_{HbR}\) c mean rCBF d mean firing rate, e mean theta LFP power and f mean ICP in different treatment and control conditions, respectively. All data were recorded every 20 min since the therapeutic agent was injected at the time point of 120 min. The data acquisition process lasted for 5 min at each time point