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Fig. 8 | BioMedical Engineering OnLine

Fig. 8

From: Screening differential circular RNAs expression profiles in Vulvar Lichen Sclerosus

Fig. 8

Pathway enrichment analysis of differentially expressed genes. A GO enrichment analysis of VLS differential genes. The functional characterization information of the calculation was the amount of abnormal genes enriched into the item. B GO enrichment scatter plot of VLS differential genes. In the horizontal axis, Rich Factor represented the number of differential genes located in the GO/the total number of genes located in the GO (Rich Factor = S gene number/B gene number). The higher the Rich Factor was, the higher the enrichment degree of GO. The ordinate was GO_TERM which was the GO function comment. In the scatter plot, the size of the dot represented the number of genes with significant differences that S gene number matched to a single GO, the color of the dot represented the P value of enrichment analysis, namely the significance of enrichment, and the p-value less than 0.05 indicates significant enrichment. C KEGG enrichment analysis of VLS differential genes. The value of − log10 (p value) was important for enrichment. The larger value, the more significant the consequence. The amount of genes was equal to the amount of genes enriched in the clause. The richness factors were the percentage of the amount of genes in the way, which was abnormally expressed in the overall amount of genes in the way. The greater enrichment factors, the higher enrichment degrees. Vertical axis was the appellation of enrichment project

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