Fig. 4
In vitro cytotoxicity of free irinotecan and the antitumor activity of CPT-11-loaded DSPE-PEG2000 targeting EGFR liposome. A Cell viability of HCT116, SW620, CW-2 and LoVo colon cancer cells using CCD18Co normal primary cells to control CRC toxicity. B In vitro cytotoxicity of free CPT-11 at the concentration of 1, 5, 10, 50 and 100 μg/mL; C the antitumor activity of CPT-11-loaded DSPE-PEG2000 targeting EGFR liposome in vitro; D survival rate of cancer cells treated with free CPT-11, CPT-11-Lipo and EGFR-Lipo-CPT-11, compared with the normal primary cells (control), generated the lowest (**p < 0.01, ***p < 0.001)