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Fig. 6 | BioMedical Engineering OnLine

Fig. 6

From: Restoration of Cullin3 gene expression enhances the improved effects of sonic hedgehog signaling activation for hypertension and attenuates the dysfunction of vascular smooth muscle cells

Fig. 6

Upregulation of CUL3 expression combined with activation of SHH signaling affected the expression of proteins related to SHH signaling in hypertension mouse model induced by Ang II. Western blot analysis was utilized for the detection of SHH, Smo, Gli and CUL3 expression in abdominal aortic tissues in each group. *P < 0.05, **P < 0.01 vs. normal; ##P < 0.01, ###P < 0.001 vs. model; P < 0.05, P < 0.01, P < 0.001 vs. model + NC + SAG

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