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Fig. 2 | BioMedical Engineering OnLine

Fig. 2

From: Restoration of Cullin3 gene expression enhances the improved effects of sonic hedgehog signaling activation for hypertension and attenuates the dysfunction of vascular smooth muscle cells

Fig. 2

Inhibition of SHH signaling affected the proliferation, migration, oxidative stress and apoptosis of VSMCs induced by Ang II. A Assessment of cell viability with a CCK-8 assay. B Determination of cell migration using Transwell migration assay. Magnification, × 100. C Analysis of cell apoptosis by TUNEL staining. Magnification, × 200. D The level of ROS was examined with a commercial available kit. E Expression of proteins related to SHH signaling was evaluated with western blot assay. *P < 0.05, P < 0.001 vs. control; #P < 0.05, ###P < 0.001 vs. Ang II

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BioMedical Engineering OnLine

ISSN: 1475-925X

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