Table 1 GO and pathway enrichment analysis of downregulated DEGs in GBM
From: Identification of novel prognostic targets in glioblastoma using bioinformatics analysis
Category | Term | Count, n | p value |
|---|---|---|---|
GOTERM_BP_DIRECT | GO:0,043,547 ~ positive regulation of GTPase activity | 17 | 0.0099 |
|  | GO:0,035,556 ~ intracellular signal transduction | 15 | 0.0027 |
|  | GO:0,007,155 ~ cell adhesion | 14 | 0.0192 |
|  | GO:0,006,468 ~ protein phosphorylation | 13 | 0.0387 |
GOTERM_CC_DIRECT | GO:0,016,021 ~ integral component of membrane | 99 | 0.0019 |
|  | GO:0,005,886 ~ plasma membrane | 90 | 4.13E−05 |
|  | GO:0,005,622 ~ intracellular | 31 | 0.013 |
|  | GO:0,005,887 ~ integral component of plasma membrane | 30 | 0.043 |
GOTERM_MF_DIRECT | GO:0,005,524 ~ ATP binding | 32 | 0.0383 |
|  | GO:0,005,509 ~ calcium ion binding | 18 | 0.0409 |
|  | GO:0,004,674 ~ protein serine/threonine kinase activity | 12 | 0.0261 |
|  | GO:0,004,672 ~ protein kinase activity | 11 | 0.0437 |
KEGG_PATHWAY | hsa04144:Endocytosis | 9 | 0.0211 |
| Â | hsa04010:MAPK signaling pathway | 9 | 0.0273 |
| Â | hsa04723:Retrograde endocannabinoid signaling | 8 | 0.00055 |
| Â | hsa04921:Oxytocin signaling pathway | 7 | 0.0198 |