| |
Parameters (unit)
|
Value
|
Control
|
OVX
|
OVX + PTH
|
p†
|
|---|
|
Density
|
aBMD (g/cm2)
|
Mediand
|
146.0a
|
139.0b
|
147.0a
|
0.306
|
|
IQR
|
16.5
|
12.0
|
15.0
| |
|
Mean
|
144.2
|
137.4
|
143.8
| |
|
SD
|
8.5
|
5.6
|
7.5
| |
|
Cancellous bone
|
BV/TV (%)
|
Mediand
|
56.957ab
|
49.977a
|
62.111b
|
0.065
|
|
IQR
|
10.843
|
21.926
|
12.542
| |
|
Mean
|
55.408
|
46.699
|
62.699
| |
|
SD
|
5.356
|
11.525
|
6.196
| |
|
TbTh (mm)
|
Mediand
|
0.136a
|
0.128a
|
0.155b
|
0.008
|
|
IQR
|
0.017
|
0.030
|
0.008
| |
|
Mean
|
0.136
|
0.127
|
0.155
| |
|
SD
|
0.009
|
0.015
|
0.004
| |
|
TbSp (mm)
|
Mediand
|
0.162a
|
0.170a
|
0.135a
|
0.164
|
|
IQR
|
0.022
|
0.088
|
0.042
| |
|
Mean
|
0.160
|
0.172
|
0.135
| |
|
SD
|
0.011
|
0.040
|
0.020
| |
|
TbN (1/mm)
|
Mediand
|
4.140a
|
3.587a
|
4.076a
|
0.357
|
|
IQR
|
0.335
|
1.278
|
0.679
| |
|
Mean
|
4.062
|
3.617
|
4.031
| |
|
SD
|
0.156
|
0.638
|
0.341
| |
|
Cortical bone
|
CtTh (mm)
|
Mediand
|
0.451a
|
0.513a
|
0.520a
|
0.326
|
|
IQR
|
0.140
|
0.055
|
0.050
| |
|
Mean
|
0.477
|
0.514
|
0.513
| |
|
SD
|
0.075
|
0.029
|
0.028
| |
|
vBMD (g/cm3)
|
Mediand
|
1.076a
|
1.060a
|
1.071a
|
0.402
|
|
IQR
|
0.065
|
0.020
|
0.030
| |
|
Mean
|
1.058
|
1.055
|
1.068
| |
|
SD
|
0.037
|
0.009
|
0.015
| |
|
CSA (mm2)
|
Mediand
|
3.016ab
|
2.618a
|
2.852b
|
0.018
|
|
IQR
|
1.076
|
0.127
|
0.943
| |
|
Mean
|
3.265
|
2.618
|
3.173
| |
|
SD
|
0.617
|
0.067
|
0.559
| |
|
BSI
|
Mediand
|
3.246a
|
2.763b
|
3.084a
|
0.013
|
|
IQR
|
0.997
|
0.173
|
0.956
| |
|
Mean
|
3.433
|
2.762
|
3.388
| |
|
SD
|
0.524
|
0.089
|
0.593
| |
|
Mechanical strength
|
Maximum fracture force (N)
|
Mediand
|
114.1a
|
80.6b
|
102.3a
|
0.046
|
|
IQR
|
30.2
|
21.1
|
24.2
| |
|
Mean
|
108.5
|
84.3
|
104.2
| |
|
SD
|
15.2
|
12.8
|
12.3
| |
- aBMD areal bone mineral density; BV/TV bone volume/total volume; TbTh trabecular bone thickness; TbSp trabecular bone separation; TbN trabecular bone number; CtTh cortical bone thickness; vBMD volumetric bone mineral density; CSA cross-sectional area; BSI bone strength index (vBMD × CSA); IQR interquartile range; OVX ovariectomy; PTH parathyroid hormone
- dMann–Whitney exact tests were conducted for post hoc pairwise comparisons; medians in the same row with the same letter (a, b, or c) do not significantly differ
- †Kruskal–Wallis test
