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Table 1 Maximum fracture force, bone mineral density, and cortical and cancellous bone structure parameters of the femoral neck for the three groups

From: Intermittent parathyroid hormone treatment affects the bone structural parameters and mechanical strength of the femoral neck after ovariectomy-induced osteoporosis in rats

  Parameters (unit) Value Control OVX OVX  +  PTH p
Density aBMD (g/cm2) Mediand 146.0a 139.0b 147.0a 0.306
IQR 16.5 12.0 15.0  
Mean 144.2 137.4 143.8  
SD 8.5 5.6 7.5  
Cancellous bone BV/TV (%) Mediand 56.957ab 49.977a 62.111b 0.065
IQR 10.843 21.926 12.542  
Mean 55.408 46.699 62.699  
SD 5.356 11.525 6.196  
TbTh (mm) Mediand 0.136a 0.128a 0.155b 0.008
IQR 0.017 0.030 0.008  
Mean 0.136 0.127 0.155  
SD 0.009 0.015 0.004  
TbSp (mm) Mediand 0.162a 0.170a 0.135a 0.164
IQR 0.022 0.088 0.042  
Mean 0.160 0.172 0.135  
SD 0.011 0.040 0.020  
TbN (1/mm) Mediand 4.140a 3.587a 4.076a 0.357
IQR 0.335 1.278 0.679  
Mean 4.062 3.617 4.031  
SD 0.156 0.638 0.341  
Cortical bone CtTh (mm) Mediand 0.451a 0.513a 0.520a 0.326
IQR 0.140 0.055 0.050  
Mean 0.477 0.514 0.513  
SD 0.075 0.029 0.028  
vBMD (g/cm3) Mediand 1.076a 1.060a 1.071a 0.402
IQR 0.065 0.020 0.030  
Mean 1.058 1.055 1.068  
SD 0.037 0.009 0.015  
CSA (mm2) Mediand 3.016ab 2.618a 2.852b 0.018
IQR 1.076 0.127 0.943  
Mean 3.265 2.618 3.173  
SD 0.617 0.067 0.559  
BSI Mediand 3.246a 2.763b 3.084a 0.013
IQR 0.997 0.173 0.956  
Mean 3.433 2.762 3.388  
SD 0.524 0.089 0.593  
Mechanical strength Maximum fracture force (N) Mediand 114.1a 80.6b 102.3a 0.046
IQR 30.2 21.1 24.2  
Mean 108.5 84.3 104.2  
SD 15.2 12.8 12.3  
  1. aBMD areal bone mineral density; BV/TV bone volume/total volume; TbTh trabecular bone thickness; TbSp trabecular bone separation; TbN trabecular bone number; CtTh cortical bone thickness; vBMD volumetric bone mineral density; CSA cross-sectional area; BSI bone strength index (vBMD  ×  CSA); IQR interquartile range; OVX ovariectomy; PTH parathyroid hormone
  2. dMann–Whitney exact tests were conducted for post hoc pairwise comparisons; medians in the same row with the same letter (a, b, or c) do not significantly differ
  3. Kruskal–Wallis test