Skip to main content

Table 1 Maximum fracture force, bone mineral density, and cortical and cancellous bone structure parameters of the femoral neck for the three groups

From: Intermittent parathyroid hormone treatment affects the bone structural parameters and mechanical strength of the femoral neck after ovariectomy-induced osteoporosis in rats

 

Parameters (unit)

Value

Control

OVX

OVX  +  PTH

p

Density

aBMD (g/cm2)

Mediand

146.0a

139.0b

147.0a

0.306

IQR

16.5

12.0

15.0

 

Mean

144.2

137.4

143.8

 

SD

8.5

5.6

7.5

 

Cancellous bone

BV/TV (%)

Mediand

56.957ab

49.977a

62.111b

0.065

IQR

10.843

21.926

12.542

 

Mean

55.408

46.699

62.699

 

SD

5.356

11.525

6.196

 

TbTh (mm)

Mediand

0.136a

0.128a

0.155b

0.008

IQR

0.017

0.030

0.008

 

Mean

0.136

0.127

0.155

 

SD

0.009

0.015

0.004

 

TbSp (mm)

Mediand

0.162a

0.170a

0.135a

0.164

IQR

0.022

0.088

0.042

 

Mean

0.160

0.172

0.135

 

SD

0.011

0.040

0.020

 

TbN (1/mm)

Mediand

4.140a

3.587a

4.076a

0.357

IQR

0.335

1.278

0.679

 

Mean

4.062

3.617

4.031

 

SD

0.156

0.638

0.341

 

Cortical bone

CtTh (mm)

Mediand

0.451a

0.513a

0.520a

0.326

IQR

0.140

0.055

0.050

 

Mean

0.477

0.514

0.513

 

SD

0.075

0.029

0.028

 

vBMD (g/cm3)

Mediand

1.076a

1.060a

1.071a

0.402

IQR

0.065

0.020

0.030

 

Mean

1.058

1.055

1.068

 

SD

0.037

0.009

0.015

 

CSA (mm2)

Mediand

3.016ab

2.618a

2.852b

0.018

IQR

1.076

0.127

0.943

 

Mean

3.265

2.618

3.173

 

SD

0.617

0.067

0.559

 

BSI

Mediand

3.246a

2.763b

3.084a

0.013

IQR

0.997

0.173

0.956

 

Mean

3.433

2.762

3.388

 

SD

0.524

0.089

0.593

 

Mechanical strength

Maximum fracture force (N)

Mediand

114.1a

80.6b

102.3a

0.046

IQR

30.2

21.1

24.2

 

Mean

108.5

84.3

104.2

 

SD

15.2

12.8

12.3

 
  1. aBMD areal bone mineral density; BV/TV bone volume/total volume; TbTh trabecular bone thickness; TbSp trabecular bone separation; TbN trabecular bone number; CtTh cortical bone thickness; vBMD volumetric bone mineral density; CSA cross-sectional area; BSI bone strength index (vBMD  ×  CSA); IQR interquartile range; OVX ovariectomy; PTH parathyroid hormone
  2. dMann–Whitney exact tests were conducted for post hoc pairwise comparisons; medians in the same row with the same letter (a, b, or c) do not significantly differ
  3. Kruskal–Wallis test