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Table 2 The death of CLL in 1990 and 2019 and its temporal trends

From: The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden of disease study 2019

 

1990

2019

1990–2019

Death cases

No*102 (95% CI)

ASDR/100,000

No. (95% CI)

Death cases

No*102 (95% CI)

ASDR/100,000

No. (95% CI)

EAPC

No. (95% CI)

Overall

215.48 (198.11–230.27)

0.40 (0.37–0.43)

446.13 (403.93–500.74)

0.58 (0.52–0.65)

1.17 (1.07–1.27)

Sex

 Male

110.64 (96.40–119.16)

0.41 (0.36–0.44)

223.06 (199.88–263.45)

0.57 (0.52–0.68)

1.13 (1.03–1.23)

 Female

104.84 (94.93–115.07)

0.39 (0.36–0.43)

223.06 (198.58–250.84)

0.58 (0.51–0.65)

1.21 (1.12–1.31)

Socio-demographic factor

 High SDI

99.73 (90.31–106.73)

1.21 (1.10–1.30)

153.12 (134.33–185.62)

1.51 (1.33–1.83)

0.53 (0.48–0.59)

 High-middle SDI

57.98 (52.16–63.41)

0.50 (0.45–0.55)

118.76 (107.42–131.33)

0.83 (0.75–0.92)

1.70 (1.62–1.78)

 Middle SDI

24.93 (20.97–28.39)

0.15 (0.12–0.17)

79.10 (69.96–91.07)

0.33 (0.29–0.38)

3.09 (2.95–3.24)

 Low-middle SDI

22.01 (18.28–26.25)

0.19 (0.16–0.23)

65.06 (56.04–76.12)

0.37 (0.32–0.43)

2.20 (2.07–2.34)

 Low SDI

10.73 (8.47–13.10)

0.20 (0.16–0.25)

79.10 (69.96–91.07)

0.26 (0.22–0.31)

0.92 (0.77–1.06)

Region

 Andean Latin America

0.31 (0.26–0.39)

0.08 (0.07–0.10)

1.31 (1.02–1.62)

0.21 (0.16–0.25)

3.61 (3.42–3.80)

 Australasia

2.53 (2.27–2.90)

1.25 (1.12–1.43)

4.97 (4.16–6.19)

1.71 (1.43–2.13)

0.82 (0.77–0.88)

 Caribbean

1.05 (0.93–1.16)

0.30 (0.26–0.33)

2.09 (1.74–2.46)

0.44 (0.37–0.52)

1.45 (1.33–1.56)

 Central Asia

1.55 (1.31–1.75)

0.22 (0.19–0.25)

2.57 (2.14–3.12)

0.27 (0.23–0.33)

0.62 (0.49–0.75)

 Central Europe

10.42 (9.46–12.72)

0.85 (0.77–1.03)

26.43 (22.34–31.60)

2.31 (1.96–2.77)

3.76 (3.71–3.82)

 Central Latin America

1.86 (1.66–1.99)

0.11 (0.10–0.12)

5.93 (4.91–7.21)

0.24 (0.20–0.29)

2.51 (2.34–2.67)

 Central Sub-Saharan Africa

0.58 (0.40–0.85)

0.10 (0.07–0.15)

2.66 (1.79–3.88)

0.20 (0.14–0.29)

2.39 (2.21–2.56)

 East Asia

14.26 (10.86–18.72)

0.12 (0.09–0.15)

48.41 (40.03–59.74)

0.33 (0.27–0.41)

4.34 (4.18–4.50)

 Eastern Europe

22.15 (18.18–25.83)

0.98 (0.80–1.14)

31.47 (27.70–35.34)

1.50 (1.32–1.68)

1.33 (1.28–1.39)

 Eastern Sub-Saharan Africa

4.13 (3.17–5.21)

0.22 (0.17–0.27)

11.89 (9.58–14.73)

0.29 (0.23–0.36)

1.07 (0.93–1.21)

 High-income Asia Pacific

1.96 (1.81–2.32)

0.11 (0.10–0.13)

4.19 (3.44–5.37)

0.22 (0.18–0.29)

2.42 (2.25–2.59)

 High-income North America

44.69 (40.00–47.37)

1.59 (1.42–1.69)

66.96 (59.17–81.04)

1.84 (1.62–2.22)

0.10 (0.05–0.15)

 North Africa and Middle East

5.58 (4.41–6.85)

0.16 (0.13–0.20)

15.70 (13.32–18.90)

0.26 (0.22–0.31)

1.58 (1.43–1.74)

 Oceania

0.02 (0.01–0.02)

0.03 (0.02–0.03)

0.04 (0.03–0.05)

0.03 (0.02–0.04)

0.00 (− 0.42–0.41)

 South Asia

25.35 (20.86–30.63)

0.23 (0.19–0.28)

78.76 (66.31–93.69)

0.44 (0.37–0.52)

2.11 (1.99–2.24)

 Southeast Asia

3.80 (3.17–4.61)

0.08 (0.07–0.10)

12.98 (10.59–16.34)

0.19 (0.16–0.24)

2.99 (2.79–3.18)

 Southern Latin America

2.19 (1.91–2.46)

0.44 (0.39–0.50)

3.78 (3.31–4.51)

0.57 (0.50–0.68)

0.45 (0.36–0.54)

 Southern Sub-Saharan Africa

3.25 (2.68–3.77)

0.62 (0.51–0.72)

7.15 (5.97–8.06)

0.91 (0.76–1.03)

1.44 (1.36–1.51)

 Tropical Latin America

2.68 (2.46–2.87)

0.18 (0.16–0.19)

8.62 (7.51–10.10)

0.39 (0.34–0.45)

2.88 (2.75–3.02)

 Western Europe

63.00 (57.08–66.86)

1.64 (1.48–1.74)

100.43 (86.91–119.83)

2.30 (1.99–2.75)

1.02 (0.98–1.07)

 Western Sub-Saharan Africa

4.12 (3.41–4.81)

0.21 (0.18–0.25)

9.82 (7.89–11.58)

0.22 (0.17–0.25)

0.02 (− 0.13–0.16)

  1. CLL, chronic lymphocytic leukemia; ASDR, age-standardized death rate; EAPC, estimated annual percentage changes; SDI, social-demographic index